ISSN:
1432-0428
Keywords:
Plasma glucose
;
insulin
;
C-peptide
;
meals
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Postprandial plasma glucose, insulin and C-peptide profiles were studied in eight normal subjects, in the afternoon or in the evening. Two to five synchronous oscillations, with a mean period of 51 to 112 min were detected. The oscillations were highest after meals and were then damped, reverting to fasting levels after up to 340 min. Additional short-term oscillations, with periods of 20–30 min and 9–14 min, were observed. Cross-correlation studies of glucose and insulin and of insulin and C-peptide revealed a high correlation in the frequency bands considered. The synchronous oscillations of insulin and C-peptide suggest cyclic variations in pancreatic secretion rather than cyclic changes in insulin degradation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00275742
