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Osteogenic sarcoma complicating osteogenesis imperfecta tarda (1978)

Lasson, U. ; Harms, D. ; Wiedemann, H. -R.

Springer

European journal of pediatrics 129 (1978), S. 215-218

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ISSN: 1432-1076

Keywords: Osteogenesis imperfecta tarda ; Osteogenic sarcoma

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract We describe the case history of a 13 years old boy who developed osteogenic sarcoma of the left thigh, six years after diagnosis of osteogenesis imperfecta tarda with a positive family history. Only four other patients with this disease combination are reported in the literature. Preoperative treatment with high-dose Methotrexate caused marked tumor regression, as shown at examination of amputation material. The inter-relationships between the two disorders are discussed and the literature is briefly reviewed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00442166

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