ISSN:
1432-1076
Keywords:
Neutropenic children
;
Granulocyte transfusions
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Fifteen children with haematological diseases received an average of 10 granulocyte transfusions each, with 4.7×1010 granulocytes per m2 body surface area (BSA) per transfusion. All patients except one had less than 100 granulocytes per μl blood combined with aplasia or hypoplasia of granulopoiesis. Thirteen patients were transfused therapeutically because of fever and/or severe local lesions unresponsive to antibiotic therapy. Two patients, who were transfused prophylactically after bone-marrow transplantation (BMT), were in excellent clinical condition during the entire period of granulocyte transfusions in spite of severe granulocytopenia. All patients except one showed definite clinical benefit from granulocyte transfusions. The non-responding patient had leukocyte antibodies.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00442100
