ISSN:
0942-0940
Keywords:
Brain tumour
;
interferon
;
natural killer
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The anti-tumour effect of mouse interferon (IFN) on an intracranially transplanted 203-glioma in C 57 BL mice and the natural killer (NK) activity of spleen cells were studied. As a clinical trial, five patients with glioblastomas were treated with human fibroblast IFN and the anti-tumour effect of IFN and the NK activity of peripheral blood lymphocytes were also studied. The NK activity increased after the beginning of IFN therapy but there was no remarkable antitumour effect of IFN in both mouse and human studies. There was no marked correlation between the increased NK activity and the anti-tumour effect of IFN in this study.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01401780