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  • Articles: DFG German National Licenses  (13)
  • 1995-1999
  • 1990-1994  (13)
  • 1990  (13)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Computing 44 (1990), S. 365-368 
    ISSN: 1436-5057
    Keywords: 65D07 ; 41A15 ; Positive spline interpolation ; sufficient and necessary existence condition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Es wird eine hinreichend und notwendige Bedingung für die Positivität von rational-kubischen Splines angegeben, welche sich leicht überprüfen läßt. Sie ist bei Interpolationsdaten mit positiven Ordinaten durch hinreichend große Rationalitätsparameter stets erfüllbar.
    Notes: Abstract By means of a finite set of inequalities a sufficient and necessary condition for the positivity of rational cubic splines is given which holds true whenever the rationality parameters are sufficiently large.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Computing 44 (1990), S. 245-258 
    ISSN: 1436-5057
    Keywords: 65D07 ; 41A15 ; Convex or monotone area true splines ; sufficient and necessary existence conditions ; construction of splines with minimal mean curvature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Gegenstand der Arbeit ist die flächentreue Approximation von Histogrammen durch rational-quadratischeC 1-Splines unter Zusatzbedingungen wie Konvexität oder Monotonie. Für derartige Aufgaben werden hinreichende und notwendige Existenzbedingungen in algorithmischer Form angegeben, und es ergibt sich, daß sich diese Bedingungen bei konvexen oder monotonen Histogrammen durch passende Wahl der Rationalitätsparameter stets erfüllen lassen. Da die genannten Aufgaben, sofern überhaupt, im allgemeinen nicht eindeutig lösbar sind, werden Histosplines mit minimaler Gesamtkrümmung ermittelt.
    Notes: Abstract In this paper the area true approximation of histograms by rational quadraticC 1-splines is considered under constraints like convexity or monotonicity. For the existence of convex or monotone histosplines sufficient and necessary conditions are derived, which always can be satisfied by choosing the rationality parameters appropriately. Since the mentioned problems are in general not uniquely solvable histo-splines with minimal mean curvature areconstructed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 68 (1990), S. 191-198 
    ISSN: 1432-1440
    Keywords: Hyponatremia ; Pontine myelinolysis ; Alcoholism ; Sodium substitution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Central pontine myelinolysis is a process of demyelinisation with variable neurological symptoms related to the localization. Predisposing factors are alcoholism and malnutrition. Rapid correction of severe hyponatremia is suspected to be a primary cause for central pontine myelinolysis. We report a 43 year old chronic alcoholic and polytoxicomanic female patient, who was admitted comatose with a serum sodium level of 94 mmol/l, caused by a syndrome of inappropriate ADH secretion. After initial improvement under careful sodium correction, the patients neurologic condition degraded progressively and within 4 weeks she developed a “locked-in”-syndrome. Only then the suspected central pontine myelinolysis could be demonstrated in nuclear magnetic resonance and computer tomography. We presume that, although sodium correction was done relatively slowly in this patient, it probably contributed to her development of central pontine myelinolysis all the same. Due to this case we review the literature on correction of hyponatremia, which shows growing evidence that it should start early but be continued very slowly (rise in serum-Na: max. 0,6 mmol/l/h) and requires frequent laboratory controls.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0942-0940
    Keywords: Intracranial pressure ; cerebral blood flow ; autoregulation ; angiotensin converting enzyme inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fourteen patients with normal pressure hydrocephalus had the autoregulation of cerebral blood flow (CBF) and intracranial pressure (ICP) investigated. In 8 of the patients the effect of Captopril on ICP and CBF was also investigated. The mean arterial blood pressure (MABP) was 109 mmHg (intra-arterially), and ICP was 11 mmHg (intraventricularly). Changes in global CBF were estimated by the arterio-venous oxygen difference method. The autoregulation of CBF was present in 13 of the patients (p 〈 0.01). The lower limit of CBF autoregulation was 86% of the baseline perfusion pressure. One hour after 50 mg of captopril perorally, MABP was reduced 16 mmHg, and ICP and CBF were unchanged. The autoregulation was maintained and the lower limit was decreased 19 mmHg. Thus patients would be expected to benefit from captopril treatment in hypotensive anaesthesia.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 31 (1990), S. 229-236 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of azelastine, an orally effective antiasthmatic/antiallergic drug, on the generation of oxygenderived free radicals in phagocytes was investigated using different chemiluminescence-assays. The chemiluminescence (CL) of both human polymorphonuclear granulocytes (PMNL) and guinea-pig alveolar macrophages (AM) was induced either by phorbol myristate acetate (PMA) or zymosan and amplified either by lucigenin or DMNH (7-dimethylamino-naphthalene-1,2-dicarbonic-acidhydrazide). The inhibitory effect of azelastine was dependent on the inducer employed and the condition and type of cells used. Azelastine reduced PMA-induced CL concentration-dependently in both PMNL (IC30=3.9 μM) and AM (IC30=9.8 μM). In AM zymosan-induced CL was inhibited 21.7% by 10 μM azelastine, whereas in PMNL it remained unchanged up to 10 μM azelastine. Azelastine has a significantly stronger inhibitory effect (IC30=4.2 μM) on oxygen free radical generation in AM primed by fetal calf serum than in unprimed AM. Based on present results it is likely that azelastine inhibitis oxygen-derived free radical generation by interaction with protein kinase C.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 102 (1990), S. 11-13 
    ISSN: 0942-0940
    Keywords: Intracranial pressure ; cerebral blood flow ; perfusion pressure ; nimodipine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Eight patients with normal-pressure hydrocephalus (NPH) were studied. The resting mean arterial blood pressure (MABP) was 100 (90–125)mmHg and the mean intracranial pressure (ICP) was 11 (5–17)mmHg. ICP and MABP were continuously measured intraventricularly and intra-arterially, respectively. Changes in global cerebral blood flow (CBF) were estimated by the arteriovenous oxygen difference method. Intravenous nimodipine (15 microgram/kg/hour) was given in the first 2 hours and 30 microgram/kg/hour in the next 2 hours. MABP was reduced 23 (4–47)mmHg (p〈0.05). ICP was increased 3 (0–10)mmHg (p 〈 0.05). CBF was unchanged in the group on the whole, but in 4 of patients a major drop in perfusion pressure was seen, and CBF decreased 6, 11, 23 and 34%, respectively. Thus these findings underline the importance of maintaining the perfusion pressure under treatment with nimodipine.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1041
    Keywords: propranolol ; cerebral blood flow ; cerebral oxygen metabolism ; CO2 reactivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of acute and long-term treatment with propranolol on cerebral blood flow (CBF) and the cerebral metabolic rate of oxygen (CMRO2) has been studied in 8 young healthy volunteers. CBF was measured by 133Xe-inhalation and single photon emission computer tomography, and CMRO2 was calculated from the arterio-venous oxygen difference and CBF. Studies were done before and 1 h after i. v. injection of 5 mg propranolol and after three weeks on oral propranolol 80 mg/d for 1 week and 160 mg/d for 2 weeks. Cerebrovascular CO2 reactivity in terms of the A – V oxygen difference was tested on all three occasions during hypercapnia and hyperventilation. CBF, CMRO2 and cerebrovascular CO2 reactivity remained stable both after acute and after 3 weeks of treatment with propranolol.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of chemical ecology 16 (1990), S. 2135-2143 
    ISSN: 1573-1561
    Keywords: Philanthus triangulum ; Hymenoptera ; Sphecidae ; Philanthinae ; beewolf ; (Z)-11-eicosen-1-ol ; 10-nonadecen-2-one ; nonadecenal ; eicosenal ; pheromone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Males of the European and African beewolf,Philanthus triangulum, possess a sex specific mandibular gland secretion that is used for marking plant stems in mating territories. The secretion is composed of 90% (Z)-11-eicosen-1-ol plus small amounts of 10-nonadecen-2-one, nonadecenal, octadecanoic and octadecenoic acids, and eicosenal. The chemistry of this secretion differs markedly from the secretions of North AmericanPhilanthus, which consist of a larger number of components that possess different chemical functionalities and are more volatile. We postulate that the chemical differences betweenP. triangulum and its New World relatives reflect phylogenetic differences plus a possible reduced necessity for species isolating mechanisms inP. triangulum.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular histology 22 (1990), S. 234-244 
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The pathway of interleukin 1 (IL-1) secretion from the cell remains unclear. IL-1β is the major form produced by human monocytes, and is synthesized as a precursor of 35kDa which is processed to the extracellular biologically active 17kDa form. We have examined the intracellular localization of IL-1β in lipopolysaccharide (LPS)-stimulated human peripheral blood monocytes, by immunocytochemistry and immunoprecipitation of subcellular fractions. LPS treatment slightly damaged the cells. Unstimulated cells showed very little immunolabelling. In contrast, there was heavy immunolabelling on LPS stimulated cells. Immunolabelling occured within the cytoplasm, nucleus and mitochondria. There was no immunolabelling on the membranous secretory organelles and the plasma membrane. Blebs of cytoplasm budding from the cell surface were immunolabelled, suggesting an alternative route of secretion of IL-1β from the cell. Immunoprecipitation studies confirmed these results.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 81 (1990), S. 215-222 
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Using a low-temperature calorimeter annealing effects were investigated in high-purity aluminium of varying grades of purity (Al 99.99, Al 99.999 and Al 99.9999) which had been subjected to deformation by torsion at liquid nitrogen. For the purpose of comparison, some residual resistivity measurements were performed on deformed and quenched Al 99.999. The calorimetric signals comprises two consecutive peaks (low-temperature peak and high-temperature peak) for each degree of deformation and purity. The low-temperature peak, with a maximum at 200 K-210 K, lies in the temperature range stage III, well-known from isochronous resistivity measurements. The effective activation energy of the annealing defects in this peak has the valueQ m=0.62 eV/atom averaged over all degrees of deformation and purity, and is thus close to the known values of the activation energy of vacancy migration. Throughout the high-temperature peak, the position of which on the temperature scale depends strongly on the degree of deformation and purity, the processes of primaty recrystallization and dislocation recovery take place in the material. The coincidence of this peak with the changes of mechanical and electrical properties are in accordance with this interpretation. Thus to the usual nomenclature for isochronous resistance measurements, one may designate this peak a “stage V” reaction peak. In this paper the particular results of the low-temperature peak (“stage III” peak) are analysed and discussed. Then the experimental data are compared with the literature data derived from other measuring procedures.
    Type of Medium: Electronic Resource
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