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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 69 (1998), S. 1132-1134 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Effects of cesium related reactions are investigated using a simulation code for H− ion sources. Effects begin to appear when cesium density is 1011 cm−3, but are still small and become large when the cesium density is greater than 1012 cm−3. The H− density decreases due to electron detachment. Decreasing the plasma potential by cesium seeding results in 12% smaller H− density. The minimum of the plasma potential shown experimentally by Bacal is found to correspond to a cesium coverage of 50% with the use of Langmuir adsorption isotherm. Surface production is effective only when the cesium density is around 1011 cm−3. For cesium density greater than 1012 cm−3, the effect of the cesium related volume reaction becomes larger. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : It has been reported that inhibitors of gastric acid secretion prevent bleeding after endoscopic mucosal resection for mucosal gastric neoplasm. However, uncertain whether an histamine2-receptor antagonist or proton-pump inhibitor is more effective.Aim : To evaluate prospectively the effectiveness of famotidine or omeprazole for ulcer management after endoscopic mucosal resection.Methods : From July 2003 to October 2004, 57 patients were randomly assigned to famotidine or omeprazole for the management of endoscopic mucosal resection. Both drugs were given intravenously for the first 2 days, thereafter by mouth. The bleeding rates after endoscopic mucosal resection, the effects on the healing of endoscopic mucosal resection-induced ulceration, and cost-benefits were compared.Results : Twenty-eight patients received famotidine and 29 received omeprazole. No significant difference was observed between the two groups in patient characteristics. The bleeding rates after endoscopic mucosal resection were not significantly different (18% vs. 14%) between the groups. Similarly, no differences were seen in the size of the endoscopic mucosal resection-induced ulceration at 1, 30 and 60 days after resection between groups. The total costs of anti-secretory agents demonstrated a significant cost-benefit to those treated with famotidine (10 420 yen vs. 17 782 yen).Conclusions : Famotidine is suggested as a better alternative to omeprazole for the management of endoscopic mucosal resection, as it showed a clear cost-benefit, and the healing results after endoscopic mucosal resection were similar for the two treatment strategies.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 21 (1999), S. 69-76 
    ISSN: 1279-8517
    Keywords: Orbital muscles ; Anomalies ; Variations ; CT and MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'objet de cette étude est de décrire quelques anomalies uni et bilatérales des muscles droits orbitaires rares et jusqu'ici non rapportées (duplication, triplication, corps musculaires accessoires, ponts musculaires entre les muscles droits, fausse insertion) qui ont été trouvées par hasard au cours de dissections de 3 cadavres (un adulte et deux foetus). Les muscles releveurs de la paupière de ces individus présentaient quelques variations (bandelettes musculaires médiale et latérale) et anomalies (releveur dédoublé et unique). Des coupes des ponts intermusculaires de l'orbite d'un adulte ont été étudiées histologiquement. Un grand nombre de nerfs est distribué dans l'interstitium ; des groupes de granules de lipofuscine ont été retrouvés dans tous les myocytes. Une tentative pour expliquer les anomalies et les variations à partir de considérations sur l'anatomie développementale et comparative est faite. On cosidèrera également comment ces anomalies peuvent apparaître dans des coupes coronales telles que celles obtenues par CT scanner et IRM.
    Notes: Summary The purpose of the study is to describe some rare and hitherto unreported uni- and bilateral anomalies of the orbital rectus muscles (duplication, triplication, accessory bellies, interrectal muscular bridges, false insertion) which were found by chance during the dissections of three cadavers (one adult, two fetuses). The levator palpebrae superioris muscles in the same specimens exhibited some variations (medial and lateral muscular slips) and anomalies (bipartite and unipartite levator). Cross-sections of interrectal bridges in the orbit of an adult were investigated histologically. Numerous nerves were distributed in the interstitium; groups of lipofuscin granules were found in all the myocytes. An attempt is made to explain these anomalies and variations through consideration of developmental and comparative anatomy. The relevance of these anomalies in coronal sections such as those acquired from CT and MRI is discussed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 21 (1999), S. 69-76 
    ISSN: 1279-8517
    Keywords: Orbital muscles ; Anomalies ; Variations ; CT and MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of the study is to describe some rare and hitherto unreported uni- and bilateral anomalies of the orbital rectus muscles (duplication, triplication, accessory bellies, interrectal muscular bridges, false insertion) which were found by chance during the dissections of three cadavers (one adult, two fetuses). The levator palpebrae superioris muscles in the same specimens exhibited some variations (medial and lateral muscular slips) and anomalies (bipartite and unipartite levator). Cross-sections of interrectal bridges in the orbit of an adult were investigated histologically. Numerous nerves were distributed in the interstitium; groups of lipofuscin granules were found in all the myocytes. An attempt is made to explain these anomalies and variations through consideration of developmental and comparative anatomy. The relevance of these anomalies in coronal sections such as those acquired from CT and MRI is discussed.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Influence of applied tensile and bending strains on the local and overall transport criticalcurrent Ic and n-value at 77 K of multifilamentary Bi2223-composite superconductor was studied,where the n-value refers to the sharpness of the transition from super- to normal conducting state.Under both tensile and bending strains, the damage such as transverse and longitudinal cracking ofthe Bi2223 filaments and interfacial debonding between the filament and silver progressed. Theextent of damage and accordingly the critical current was different among the local portions. Therelation of the local current and n-value to overall ones was analyzed with a voltage summationmodel, with which the experimental result was described well. Further analysis revealed that thedistribution of local critical current could be described by the Weibull distribution function andn-value could be expressed as a function of critical current. Based on these results, a Monte Carlosimulation was carried out to predict the overall critical current from the distribution of local criticalcurrent, with which the experimental results could be described
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 319 (Sept. 2006), p. 173-180 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0827
    Keywords: Key words: Bone formation rate — Osteoclast — Osteocalcin — Indomethacin — Histomorphometry.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. We examined the bone turnover and bone mass in adjuvant-induced arthritis in rats and assessed the effects of indomethacin in this model. One hundred ten SD rats, 6 weeks of age, were assigned to 11 groups and injected with adjuvant or solvent in the right foot. Adjuvant-injected rats were orally administered indomethacin at doses of 0 (vehicle), 0.1 (low), 0.5 (medium), and 1.5 (high) mg/kg body weight from the start (day 0). Animals were sacrificed on days 0, 14 (acute phase), and 28 (chronic phase). In the arthritic-control group, serum osteocalcin level and bone mineral content of the fourth lumbar body (L4) and the femur were significantly reduced on day 14. Serum alkaline-phosphatase was increased on day 28. Trabecular bone volume of L4 was decreased on day 14, and the value was further decreased on day 28. Bone formation rate (BFR/BS) was significantly reduced on day 14, and then osteoclast number (Oc.N/BS) increased on day 28. Indomethacin treatment dose-dependently prevented increases in paw volume and osteoclast number. In the high dose group, these indices were maintained at the same level with those in the normal group. However, indomethacin treatments were not able to maintain the parameters of bone formation such as serum osteocalcin and BFR/BS values, and the trabecular bone mass decrease was only partially prevented. These data clearly indicated both reduced bone formation and increased bone resorption as the causes of bone loss in adjuvant-induced arthritis in rats. Increased bone resorption seemed to be due to the increased activity of prostaglandins, but bone formation defect would be related to other factors in this animal model.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1238
    Keywords: Key words Amino acid ; Nitrogen balance ; Slow hemodialysis ; Critically ill ; Renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: The effects of slow diurnal hemodialysis (slow HD) on amino acid losses and nitrogen balance were studied. Design: Slow HD was conducted for 10 h during the day at the dialysate flow rate of 30 ml/min. The patients received total parenteral nutrition including 40 g of amino acids (6.08 g of nitrogen). The amino acid concentrations in plasma and dialysate were determined and the daily nitrogen balance was calculated from the urea nitrogen appearance. Patients: Six critically ill patients with renal failure were entered into the study. Results: Slow HD eliminated 48.5±4.4 mmol (6.2±0.6 g) of amino acids, representing 16% of the daily amino acid load. The estimated nitrogen balance was –2.3±1.3 g/day. Amino acid nitrogen lost in the dialysate was 1.0±0.1 g, contributing 43% of the daily negative nitrogen balance. Conclusion: The amount of amino acid losses during slow HD should be taken into consideration when designing nutritional schedules for maintaining positive nitrogen balance in critically ill patients.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Previous studies from our laboratory provided evidence for the operation of signal transduction pathways involving ras, myc, and staurosporine-sensitive protein kinases in the regulation of DNA replication in irradiated cells. Because ras and myc are also involved in the signal transduction elicited in response to ligand activation of growth factor receptors, we wondered whether growth factor receptors are upstream elements in the regulation of DNA replication in irradiated cells. Here, we report on the role of insulin-like growth factor I receptor (IGF-IR) in the regulation of DNA replication in irradiated cells. We compare radiation-induced inhibition of DNA replication in BALB/c 3T3 cells with that in P6 cells. P6 cells are derived from BALB/c 3T3 cells by transfection with a vector expressing IGF-IR, leading to 30-fold overexpression. We observe a significantly stronger inhibition of DNA replication after irradiation in P6 as compared with BALB/c 3T3 cells at all doses examined. Sedimentation in alkaline sucrose gradients shows that the increased inhibition in P6 cells is due to an increased inhibition of replicon initiation, the main controlling event in DNA replication. Staurosporine at 20 nM reduces radiation-induced inhibition of DNA replication in BALB/c 3T3 cells, but has only a small effect in P6 cells. Caffeine at a concentration of 1 mM, on the other hand, removes over 60% of the inhibition in both cell lines. The results implicate IGF-IR in the regulation of DNA replication in irradiated cells, but also suggest differences between cells of different origins in the proteins involved in the regulating signal transduction pathway.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 155 (1996), S. 148-149 
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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