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  • Articles: DFG German National Licenses  (4)
  • 1995-1999  (2)
  • 1990-1994  (1)
  • 1985-1989  (1)
  • Genitofemoral nerve  (2)
  • H2-receptor antagonist  (2)
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  • Articles: DFG German National Licenses  (4)
Material
Years
  • 1995-1999  (2)
  • 1990-1994  (1)
  • 1985-1989  (1)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 21 (1999), S. 1-5 
    ISSN: 1279-8517
    Keywords: Ilioinguinal nerve ; Genitofemoral nerve ; Sports hernia ; Human gross anatomy ; Clinical anatomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chronic pain on the ventral surface of the scrotum and the proximal ventro-medial surface of the thigh especially in athletes has been diagnosed in various ways; recently, in Europe the concept of “sports hernia” has been advocated. However, since few reports discuss the detailed course of the nerves in association with the pain, we examined the cutaneous branches in the inguinal region in 54 halves of 27 adult male cadavers. From our results, in addition to the cutaneous branches from the ilioinguinal n. (in 49 of 54: 90.7%), cutaneous branches originating from the genital branches of the genitofemoral nerve were found in the inguinal region in 19 of 54 halves (35.2%). In 7 cases (in 7 of 54: 13.0%) the genital branch and the ilioinguinal nerve united in the inguinal canal. In 6 cases the genital branch pierced the inguinal lig. to enter the inguinal canal, and in three cases the genital branch pierced the border between the ligament and the aponeurosis of the obliquus externus m. to be distributed to the inguinal region. Therefore, the courses of the genital branches vary considerably, and may have a very important role in chronic groin pain produced by groin hernia. In addition, entrapment by the ligament may be a reasonable candidate for the cause of chronic groin pain.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 21 (1999), S. 1-5 
    ISSN: 1279-8517
    Keywords: Ilioinguinal nerve ; Genitofemoral nerve ; Sports hernia ; Human gross anatomy ; Clinical anatomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La douleur chronique de la face ventrale du scrotum et de la face ventro-médiale proximale de la cuisse, en particulier chez les athlètes, a été interprétée de différentes manières ; le concept de “hernie du sport” a été récemment évoqué en Europe. Cependant, depuis que quelques rapports ont décrit le trajet détaillé des nerfs en association avec la douleur, nous avons examiné les branches cutanées de la région inguinale chez 27 cadavres mâles adultes (54 dissections). D'après nos résultats, dans la région inguinale, en plus des branches cutanées provenant du nerf ilio-inguinal (dans 49 des 54 cas ; 90,7 %) des branches cutanées provenant des branches génitales du nerf génito-fémoral ont été trouvées dans 19 des 54 dissections (35,2 %). Dans sept cas (7 des 54 cas, soit 13 %) la branche génitale et le nerf ilio-inguinal étaient unis ensemble dans le canal inguinal. Dans six cas, la branche génitale traversait le ligament inguinal pour entrer dans le canal inguinal, et dans trois cas la branche génitale traversait la frontière entre le ligament et l'aponévrose du muscle oblique externe pour se distribuer à la région inguinale. Ainsi, les trajets des branches génitales sont extrêmement variables, et peuvent avoir un rôle très important dans la douleur chronique de l'aine, attribuée habituellement à la hernie de l'aine. De plus, la contrainte mécanique liée au ligament peut être raisonnablement à l'origine de la douleur chronique de l'aine.
    Notes: Summary Chronic pain on the ventral surface of the scrotum and the proximal ventro-medial surface of the thigh especially in athletes has been diagnosed in various ways; recently, in Europe the concept of “sports hernia” has been advocated. However, since few reports discuss the detailed course of the nerves in association with the pain, we examined the cutaneous branches in the inguinal region in 54 halves of 27 adult male cadavers. From our results, in addition to the cutaneous branches from the ilioinguinal n. (in 49 of 54: 90.7%), cutaneous branches originating from the genital branches of the genitofemoral nerve were found in the inguinal region in 19 of 54 halves (35.2%). In 7 cases (in 7 of 54: 13.0%) the genital branch and the ilioinguinal nerve united in the inguinal canal. In 6 cases the genital branch pierced the inguinal lig. to enter the inguinal canal, and in three cases the genital branch pierced the border between the ligament and the aponeurosis of the obliquus externus m. to be distributed to the inguinal region. Therefore, the courses of the genital branches vary considerably, and may have a very important role in chronic groin pain produced by groin hernia. In addition, entrapment by the ligament may be a reasonable candidate for the cause of chronic groin pain.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    ISSN: 1432-1041
    Keywords: famotidine ; H2-receptor antagonist ; renal insufficiency ; old age pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of the H2-receptor antagonist famotidine, after oral administration of a 20 mg tablet, has been studied in 10 elderly patients with normal renal function (CLCR≧59 ml·min−1, Mean=80 ml·min−1), 5 elderly patients with renal insufficiency (CLCR≦38 ml·min−1, Mean=15 ml·min−1), and 6 healthy young volunteers. Elimination half-life in the elderly patients with renal insufficiency was significantly prolonged compared to the elderly patients with normal renal function and the young volunteers. The correlation coefficient between creatinine clearance and the elimination rate constant of famotidine was 0.672. Mean urinary recovery of unchanged drug up to 24 h in the young volunteers was 44%. The mean renal clearance of famotidine in the young volunteers (270 ml·min−1) was substantially greater than the creatinine clearance, 128 ml·min−1, which suggests the possibility of tubular secretion of famotidine.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 38 (1990), S. 313-314 
    ISSN: 1432-1041
    Keywords: famotidine ; anuric patients ; haemodialysis ; H2-receptor antagonist ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of haemodialysis on the pharmacokinetics of oral famotidine has been studied in five elderly anuric patients. Famotidine 20 mg was administered in a cross-over design to patients on and not on haemodialysis. The elimination rate constant of haemodialysis (k) was 4.6-fold larger than the systemic elimination rate constant (ke). Although the mean maximum serum concentration of famotidine during haemodialysis (141.5 ng·ml−1) was not significantly lower than that without haemodialysis (195.6 ng·ml−1), the AUC up to 5 h during haemodialysis was significantly decreased to 58.1% of the value without it. The data suggest that famotidine is dialysable by haemodialysis.
    Type of Medium: Electronic Resource
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