Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Total quality "down under": the Australian Quality Award - an innovative model for Business Excellence (1997)
    Bradford : Emerald
    The @TQM magazine 9 (1997), S. 217-220 
    Details
    ISSN: 0954-478X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Notes the importance of countries beyond Europe in terms of the contribution of valuable ideas to the development of TQM. Looks at the introduction of the Australian Quality Award and its development from 1988 to the present day. Examines in detail the criteria and purpose of the award.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/09544789710169000
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Freeze-Trapping Isomorphous Xenon Derivatives of Protein Crystals (1997)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 30 (1997), S. 476-486 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: A simple and efficient method to prepare isomorphous derivatives of protein crystals with xenon as a heavy atom is described. The method consists of exposing a crystal to xenon gas of pressures above 5 atm ( ̃0.5 MPa) for several minutes and subsequently shock-freezing the crystal to immobilize the xenon dissolved in the mother liquor and bound to the protein. Diffraction data can the be collected with the established techniques of protein cryocrystallography. Two types of high-pressure device are described to expose a protein crystal to the required xenon pressure, permitting rapid freeze-quenching after xenon exposure. One of these devices can be used for gas pressures up to and exceeding 5.0 MPa, with a gas consumption of a few millilitres of uncompressed gas. The technique has been tested with monoclinic crystals of sperm-whale metmyoglobin, which has four xenon binding sites. The results of these experiments are described and discussed. Potential applications of this technique include-besides the classical multiwavelength anomalous diffraction (MAD) or single isomorphous replacement with anomalous scattering (SIRAS) experiments-the derivation of low-angle phase information by modifying the electron density of the solvent regions within the crystal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889897000745
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Evaluation of risk factors for the development of nephropathy in patients with IDDM: insertion/deletion angiotensin converting enzyme gene polymorphism, hypertension and metabolic control (1997)
    Springer
    Diabetologia 40 (1997), S. 327-331 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Diabetic nephropathy ; risk factors ; ACE polymorphism ; glycaemic control ; hypertension.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Diabetic nephropathy represents a major complication in patients with insulin-dependent diabetes mellitus (IDDM). Intervention trials using angiotensin-converting enzyme (ACE) inhibitors have pointed towards the important pathogenetic role of the renin-angiotensin system. Recently an insertion/deletion (I/D) polymorphism for the gene encoding the ACE has been described, the deletion type being associated with higher plasma ACE levels. As the intrarenal renin-angiotensin system might also be activated in this setting, we determined the ACE genotype together with other risk factors for the development of diabetic nephropathy in 122 patients with IDDM from a single centre with (n = 63) and without (n = 59) nephropathy. Long-term glycaemic control was evaluated using mean HbA1c values from the last 10 years. The two patient group were comparable with regard to duration of diabetes and glycaemic control as assessed by current HbA1c values. However, mean long-term HbA1c values were significantly higher in patients with diabetic nephropathy as was systemic blood pressure. The DD genotype was more prevalent in patients with renal disease. In the subgroup of patients who had had diabetes for more than 20 years (n = 90), the DD genotype was even more frequent in patients with nephropathy, and blood pressure and long-term HbA1c values were also higher in patients with renal disease. Logistic regression analysis revealed long-term glycaemic control, blood pressure and the ACE genotype to be independent risk factors for the prevalence of diabetic nephropathy. [Diabetologia (1997) 40: 327–331]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050682
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Simulation of iron fracture caused by a blast wave (1997)
    Springer
    Technical physics letters 23 (1997), S. 347-349 
    Details
    ISSN: 1090-6533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A numerical simulation is made of the fracture of iron caused by a blast wave. The numerical method is described and results of calculations using a one-dimensional formulation of three qualitatively different explosion regimes are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1134/1.1261676
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Technology and principles of tomographic image-guided interventions and surgery (1997)
    Springer
    Surgical endoscopy and other interventional techniques 11 (1997), S. 946 -956 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Interventional MRI guidance — Tomographic microtherapy — Endoscopic surgery — Image-guided surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Image guidance of instruments can be performed by fluoroscopy, ultrasound imaging, computed tomography (CT), magnetic resonance imaging (MRI), and by stereotactic navigation. During the last year, there has been significant progress in MRI instrument guidance in the field of interventional radiology. Our first 168 clinical cases of MRI-guided interventional procedures, e.g., aspiration biopsy of neoplasms and tomographic microtherapy with local interstitial chemo-ablation, confirm the feasibility of MRI guidance. An expansion of MRI guidance during surgical endoscopic procedures is currently under evaluation and the initial results of this development are presented. Tomographic-guided surgery and the implementation of MRI or CT scanning within the environment of an operating room (OR) entail specific technological requirements and OR design considerations. Fast sequences, interventional protocols, in-room monitor, as well as MR-compatible probes, cannulae, catheters, instruments, endoscopes, and auxiliary equipment that are necessary for this combined surgical image-guided approach are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900495
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    The duodenum-preserving resection of the head of the pancreas in patients with pancreas divisum (1997)
    Springer
    Der Chirurg 68 (1997), S. 180-186 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Pancreas divisum ; Chronic pancreatitis ; Surgical therapy. ; Schlüsselwörter: Pancreas divisum ; chronische Pankreatitis ; chirurgische Therapie.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Bei 1–6 % der Patienten, die sich einer endoskopisch retrograden Cholangiopancreaticographie (ERCP) unterziehen, wird ein Pancreas divisum diagnostiziert. Bei einigen dieser Patienten kommt es zu akut rezidivierenden Pankreatitisschüben und schließlich zu einer chronischen Pankreatitis (CP). Operative Verfahren bieten Aussicht auf langfristige Beschwerdebesserung und Heilung. Wir berichten über unsere Erfahrung mit der duodenumerhaltenden Pankreaskopfresektion (DEPKR) bei 12 Patienten mit Pancreas divisum und CP. In der präoperativen Abklärung fanden sich bei allen Patienten neben einem Pancreas divisum klinische, funktionelle und radiologische Zeichen einer CP. Die DEPKR wurde in allen Fällen ohne perioperative Komplikationen durchgeführt. Bei 10 Patienten zeigte sich postoperativ eine pathologische exokrine Pankreasfunktion (präoperativ bei 8 Patienten), während sich im postoperativen oralen Glucosetoleranztest (OGTT) die endokrine Funktion zweier Patienten normalisierte. Elf Patienten, die nach einer mittleren Beobachtungszeit von 31 Monaten (3–75 Monate) nachuntersucht wurden, waren bei fehlender spätpostoperativer Letalität schmerzfrei. Der OGTT zeigte bei zwei Patienten eine gestörte endokrine Pankreasfunktion. Neun Patienten mußten bei gestörter exokriner Funktion medikamentös substituiert werden. Eine Patientin wurde 10 Monate nach Erstoperation aufgrund einer Gangstenose im Bereich der Pancreaticojejunostomie mittels Neuanlage der Anastomose reoperiert. Zusammenfassend kann gesagt werden, daß die DEPKR bei Patienten mit Pancreas divisum und CP zu einer anhaltenden Beschwerdefreiheit und bei einem Teil dieser Patienten zu einer Verbesserung der endokrinen Funktion führen kann. Dieses Verfahren sollte den nicht resezierenden, operativen Eingriffen oder endoskopischen Maßnahmen vorgezogen werden.
    Notes: Summary. In 1–6 % of the patients who are investigated by endoscopic retrograde cholangio-pancreatography a pancreas divisum can be found. In some patients pancreas divisum can lead to an acute relapsing and finally chronic pancreatitis (CP). Surgical intervention in these cases seems to offer a good chance of recovery. We report our experience with the duodenum-preserving resection of the head of the pancreas in 12 patients with pancreas divisum and CP. In all patients the preoperative evaluation showed clinical, functional or radiological signs of CP. The duodenum-preserving resection of the head of the pancreas was carried out in all patients without perioperative mortality. Ten postoperative versus eight preoperative patients showed a pathological exocrine function of the pancreas. Endocrine function, measured by the oral glucose tolerance test (OGTT), improved postoperatively in two patients. Eleven patients who were investigated after a mean follow-up time of 31 months (3–75 months) were completely pain free. No late mortality occurred. OGTT revealed a diabetic endocrine function in two patients. Disturbed exocrine pancreatic function had to be substituted in nine patients. One patient had to be reoperated by duct incision and renewal of the pancreatico-jejunostomy 10 months after the first operation. In conclusion, the duodenum-preserving resection of the head of the pancreas reduced pain in all patients with pancreas divisum and CP and may lead to an improvement of endocrine pancreatic function. Other, nonresecting procedures or endoscopic interventional therapy should be avoided in these patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001040050170
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Validating the MPI-DLV Using Experience Sampling Data (1997)
    Springer
    Journal of behavioral medicine 20 (1997), S. 195-206 
    Details
    ISSN: 1573-3521
    Keywords: chronic pain ; experience sampling ; Multidimensional Pain Inventory ; Dutch version ; (MPI-DLV) ; validity assessment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract The present study investigates the relationship between scale scores on the Dutch version of the Multidimensional Pain Inventory (MPI-DLV) and data derived from comparable items from an experience sampling procedure. Fifty-seven chronic pain patients participated in the study, which lasted 6 consecutive days. Special attention was given to the relationship between the MPI-DLV pain intensity score and the mean experience sampling pain intensity score. Significant correlations were found between the MPI-DLV scales Pain Severity, Interference, Solicitous, Punishing and Distracting Responses, and Household Chores and their experience sampling analogues. A marginally significant correlation was found with regard to the MPI-DLV Life Control scale. The General Activity and Affective Distress scales had no relationship with the analogous experience sampling items. The significant correlations were regarded as further validation of the MPI-DLV. A regression analysis revealed that 58% of the variance of the experience sampling pain intensity score could be explained by the MPI-DLV present pain intensity item score.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1025534812341
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    In vivo and in vitro studies on interactions between the components of the hemolysin (HlyA) secretion machinery of Escherichia coli (1997)
    Springer
    Molecular genetics and genomics 256 (1997), S. 306-319 
    Details
    ISSN: 1617-4623
    Keywords: Key words Hemolysin secretion ; HlyD mutants ; HlyD/HlyB suppressor mutants ; TolC ; Vancomycin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The glycopeptide antibiotic vancomycin blocks cell wall synthesis in Escherichia coli only when it can reach its target site in the periplasm. In vivo, sensitivity to vancomycin is enhanced in the presence of the hemolysin (hly) determinant of E. coli or its translocator portion hlyBD. Two different mutations in hlyD alter the cell's susceptibility to vancomycin: mutations in the tolC-homologous region of hlyD increase vancomycin resistance, whereas mutations at the 3′-terminus of hlyD lead to hypersensitivity to vancomycin and to the accumulation of large periplasmic and cytoplasmic pools of this antibiotic in E. coli. These effects are only observed in the presence of functional HlyB and TolC, the two other components of the hemolysin secretion machinery. A defect in TolC causes hyperresistance to vancomycin, even when present together with a mutant HlyD protein which in the presence of TolC renders E. coli hypersensitive to vancomycin. Lipid bilayer experiments in vitro revealed specific interactions between TolC and vancomycin or HlyD protein. Second-site suppressor mutations in hlyD and hlyB were obtained, which abolish the hypersensitive phenotype caused by the 3′-terminal mutations in hlyD. Our results are compatible with the idea that (a) TolC, together with the TolC-homologous part of HlyD, forms a pore in the outer membrane through which hemolysin is released and vancomycin taken up; and (b) the C-terminal sequence of HlyD interacts with periplasmic loop(s) of HlyB to form a closed channel spanning the periplasm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004380050574
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Homozygous thermolabile methylenetetrahydrofolate reductase in schizophrenia-like psychosis (1997)
    Springer
    Journal of neural transmission 104 (1997), S. 931-941 
    Details
    ISSN: 1435-1463
    Keywords: Schizophrenia ; hyperhomocysteinemia ; thermolabile methylenetetrahydrofolate reductase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The gene for methylenetetrahydrofolate reductase (MTHFR) has shown polymorphism in the general human population. In its homozygous form, a C677T mutation occurs in more than 5% of the grown-up population and produces a thermolabile variant which reduces the overall enzyme activity to less than 30% of normal. We investigated patients with schizophrenia-like psychosis. If hyperhomocysteinemic, their DNA-genotype for thermolabile C677T mutation was determined. Seven of 11 patients, six males and one female, were homozygous for thermolabile MTHFR. One male patient was heterozygous and all three normal homozygotes were females. In the patients who were homozygous for the C677T mutation, the homocysteine concentrations did not respond to vitamin B12 but were normalized by folate supplementation. In the normal homozygotes, however, the homocysteine concentrations were reduced by vitamin B12 alone. Our results suggest that homozygosity for thermolabile MTHFR is a risk factor for schizophrenia-like psychosis. Possibly, this risk may be reduced by folate supplementation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01285561
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Sulfoximid und Sulfoximidium-Salze - Strukturen und H—Brückenbindungen (1997)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 623 (1997), S. 1168-1174 
    Details
    ISSN: 0044-2313
    Keywords: Sulfoximide ; Sulfoximidium Salts ; Structure ; Hydrogenbonding ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Sulfoximide and Sulfoximidium Salts - Structures and Hydrogen BondingIn the solid state dimethylsulfoximide (1) (orthorhombic; space group Pbca; a = 577.8, b = 931.2 and c = 1645.6 pm) makes intermolecular N—H ≡ N hydrogen bonds. The hydrogen halide salts (CH3)2S(O)NH2+Hal- ((2), Hal-=Cl-; (4), Hal-=Br-) reacts with metal halides to yield (CH3)2S(O)NH2+MHalyn- with the complex anions ((5), MHalyn-=SbCl4-; (6), MHalyn-=SbCl52-; (7), MHalyn-=SbCl6-; (8), MHalyn-=SbBr52-; (9), MHalyn-=AlCl4-). 2 crystallizes from ethanol (96%) as [(CH3)2S(O)NH2+Cl-]2 · H2O (3). The structures of 3 (monoclinic; space group P21/c; a = 917.0, b = 1344.7, c = 1080.8 pm and β = 103.8°; Z = 10), 4 (orthorhombic; space group Pbcn; a = 1028.9, b = 1132.6, c = 1074.1 pm; Z = 8) and 6 (monoclinic; space group C2/c; a = 2041.1, b = 1101.4, c = 3365.6 pm and β = 153.8°; Z = 8) are determined by X-ray analysis. In 6 Sb is coordinated in a distorted octahedra by 6 Cl in three short (mean 245,5 pm; SbCl3) and three long distances (291 to 299 pm; Cl-). Two of the chloride ions connect the Sb atoms to infinite Sb … Cl … Sb chains. Except for 7 and 9 there are bridges between the NH2 groups and the halide ions. The NH valence vibrations are discussed in view of hydrogen bonding.
    Notes: Im festen Dimethylsulfoximid (1) (orthorhombisch; Raumgruppe Pbca; a = 577,8, b = 931,2 und c = 1645,6 pm) sind zwischen den Imidgruppen N—H … N-Brückenbindungen ausgebildet. Die mit HHal darstellbaren Salze (CH3)2S(O)NH2+Hal- ((2), Hal-=Cl-; (4), Hal-=Br-) reagieren mit MHalx zu (CH3)2S(O)NH2+MHalyn- ((5), MHalyn-=SbCl4-; (6), MHalyn-=SbCl52-; (7), MHalyn-=SbCl6-; (8), MHalyn-=SbBr52-; (9), MHalyn-=AlCl4-). 2 kristallisiert aus 96% Ethanol als [(CH3)2S(O)NH2+Cl-]2 · H2O (3). Die Strukturen von 3 (monoklin; Raumgruppe P21/c; a = 917,0, b = 1344,7, c = 1080,8 pm und β = 103,8°; Z = 10), 4 (orthorhombisch; Raumgruppe Pbcn; a = 1028,9, b = 1132,6, c = 1074,1 pm; Z = 8) und 6 (monoklin; Raumgruppe C2/c; a = 2041,1, b = 1101,4, c = 3365.6 pm und β = 153,8°; Z = 8) wurden bestimmt. In 6 ist Sb verzerrt oktaedrisch von 6 Cl in drei kurzen (im Mittel 245,5 pm; SbCl3) und drei langen Abständen (291 bis 299 pm; Cl-) umgeben. Zwei der lang gebundenen Cl-Ionen verknüpfen die Sb-Atome zu unendlichen Sb … Cl … Sb-Ketten. Die NH2-Gruppen der Kationen bilden außer in 7 und in 9 H—Brückenbindungen zu den Halogenidionen. Die NH-Valenzschwingungen werden im Hinblick auf die Wasserstoffbrückenbindungen diskutiert.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19976230727
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...