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  • 1
    Electronic Resource
    Electronic Resource
    Cheyletiella dermatitis in humans, dogs and cats (2000)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 143 (2000), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2000.03869x
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  • 2
    Electronic Resource
    Electronic Resource
    Mutation and Enzyme Function in Humans (1975)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 9 (1975), S. 187-212 
    Details
    ISSN: 0066-4197
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ge.09.120175.001155
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  • 3
    Electronic Resource
    Electronic Resource
    Trifluoronitrogen(1+) radical cation. Electron spin resonance studies of radiation effects in tetrafluoronitrogen(1+) salts (1975)
    s.l. : American Chemical Society
    Inorganic chemistry 14 (1975), S. 1103-1106 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50147a028
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  • 4
    Electronic Resource
    Electronic Resource
    Cholesterol oxidase as a probe for studying membrane organisation (1978)
    [s.l.] : Nature Publishing Group
    Nature 274 (1978), S. 394-395 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 demonstrates that the cholesterol present in membranes of intact VS virus and intact human erythrocytes was essentially inaccessible to oxidation by cholesterol oxidase compared with 100% oxidation after disruption of each membrane with 0.3% sodium taurodeoxycholate. Trypsin digestion of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/274394a0
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  • 5
    Electronic Resource
    Electronic Resource
    An energetic stellar outburst accompanied by circumstellar light echoes (2003)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 422 (2003), S. 405-408 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Some classes of stars, including novae and supernovae, undergo explosive outbursts that eject stellar material into space. In 2002, the previously unknown variable star V838 Monocerotis brightened suddenly by a factor of ∼104. Unlike a supernova or nova, it did not ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature01508
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  • 6
    Electronic Resource
    Electronic Resource
    Orthologische und pathologische Oberflächenstrukturen der Portio uteri (rasterelektronenmikroskopische Studie) (1977)
    Springer
    Archives of gynecology and obstetrics 224 (1977), S. 522-523 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00679699
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  • 7
    Electronic Resource
    Electronic Resource
    Remarks on the behavioristic analysis of competitive reactions Bemerkungen zur behavioristischen Analyse von Wettbewerbsreaktionen (2000)
    Springer
    OR spectrum 22 (2000), S. 97-116 
    Details
    ISSN: 1436-6304
    Keywords: Schlüsselwörter: Wettbewerbsreaktion – Wettbewerbsstrategie – Marketing-Mix – Stochastisches Modell ; Key words: Competitive reaction – Competitive strategy – Marketing mix – Stochastic model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Description / Table of Contents: Abstract. One particularly predominant current challenge to quantitative management science is the modeling and analysis of competitive actions and reactions. Approaches following the stimulus response paradigm are able to take into account the limited access to a company's internal decision making processes. In the present paper the most significant characteristics of a behavioristic analysis of competitive reactions are described. Furthermore, a stochastic model of competitive reactions by the simultaneous use of several marketing instruments is proposed. The empirical evidence of the model will be demonstrated with POS scanner data on frequently purchased consumer goods.
    Notes: Zusammenfassung. Eine der vordringlichsten gegenwärtigen Herausforderungen an die quantitative Management-Wissenschaft ist die Modellierung und Analyse von Wettbewerbsaktionen und -reaktionen. Dem begrenzten Zugang zu unternehmensinternen Entscheidungsprozessen kann durch die behavioristische Modellierung des Wettbewerbsverhaltens entsprechend dem Stimulus-Response-Paradigma Rechnung getragen werden. Im vorliegenden Beitrag werden wesentliche Charakteristika der behavioristischen Analyse von Wettbewerbsreaktionen dargestellt. Darüber hinaus wird ein stochastisches Modell der Wettbewerbsreaktion durch den simultanen Einsatz verschiedener Marketinginstrumente vorgestellt. Die empirische Überprüfung des Modells erfolgt anhand eines POS-Scannerdatensatzes für ein Konsumgut des täglichen Bedarfs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002910050007
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  • 8
    Electronic Resource
    Electronic Resource
    Early Postoperative Transcranial Sonography (TCS), CT, and MRI after Resection of High Grade Glioma: Evaluation of Residual Tumour and its Influence on Prognosis (2000)
    Springer
    Acta neurochirurgica 142 (2000), S. 1089-1097 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Brain neoplasms; magnetic resonance imaging; tomography, X-ray computed; ultrasonics.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ Purpose. In this prospective study the results of multimodal postoperative neuro-imaging were related to the survival of patients with high grade gliomas.  Methods. All 73 patients included underwent microsurgical tumour resection and had postoperative CT and transcranial sonography (TCS) examinations. In addition, 35 of the 73 patients received an early postoperative MRI. Patients were followed up for at least one year.  Findings. At the end of the 7 year study period 56 patients had died. The median survival time was 371 days. Survival rate was significantly higher in patients with anaplastic astrocytomas and inpatients displaying complete tumour resection on MRI (log-rank-test, p〈0.05) or a small postoperative residual tumour bulk on TCS (log-rank-test, p〈0.05). Cox proportional hazards model identified histological tumour grade, postoperative Karnofsky index, complete resection based on MRI and small postoperative residual tumour mass on TCS as independent predictors of survival.  Interpretation. This study demonstrates that early postoperative neuro-imaging has prognostic implications for the survival of patients with high grade gliomas. According to our results postoperative imaging with MRI and TCS is a valuable prognostic with regard to patient survival and should therefore be implemented in postoperative follow-up. It also helps to evaluate the efficacy of adjuvant therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010070035
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  • 9
    Electronic Resource
    Electronic Resource
    Procalcitonin (PCT) in patients with abdominal sepsis (2000)
    Springer
    Intensive care medicine 26 (2000), S. S165 
    Details
    ISSN: 1432-1238
    Keywords: Key words Peritonitis ; Sepsis ; Septic courses ; Diagnosis ; Cytokines ; Procalcitonin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: To assess the accuracy of procalcitonin as a measure of severity in patients with septic abdominal illnesses and the sepsis syndrome, to compare measurements with those of other inflammatory mediators, and to predict outcome.¶Methods: We carried out a prospective clinical study from 246 patients with infective or septic episodes confirmed at laparotomy and 66 patients undergoing elective operations who acted as controls. Specimens of blood for measurement of cytokine concentrations determination were obtained daily from septic patients. In the control group specimens were obtained before operation, at the end of operation, and on each of the following days until normal recovery (day 10). Every two weeks up to 3 months for patients with metastases, who were being followed up.¶Results: Compared with other cytokines such as tumor necrosis factor αa and interleukin 6 procalcitonin was closely related to the development of infective and septic complications. 59 of 246 patients (24 %) with sepsis died. Procalcitonin concentrations preoperatively [median 2.05 compared with 4.2 ng/ml (p = 0.08)] (Mann-Whitney U-test) did not differ, but those on the days 1, 4 and at the end differed significantly [day 1: 4.9 compared with 13.8 ng/ml (p 〈 0.01); day 4: 4.8 compared with 13.0 ng/ml (p 〈 0.01) and 0.4 compared with 13.25 ng/ml (p 〈 0.01) at the end of the study]. In the control group only 7 (1.6 %) of all blood samples, were detected outside the normal range (up to 0.8 ng/ml).¶Conclusions: Procalcitonin is a new indicator of infection and sepsis. TNF and IL-6 concentrations always rise after major operations and fall in the absence of infection, indicating operative trauma. Procalcitonin is sensitive in detecting infective complications. Under routine conditions the procalcitonin concentrations seems to be valid, reproducible and detectable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340051137
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  • 10
    Electronic Resource
    Electronic Resource
    Selenium requirement for active xanthine dehydrogenase from Clostridium acidiurici and Clostridium cylindrosporum (1979)
    Springer
    Archives of microbiology 121 (1979), S. 255-260 
    Details
    ISSN: 1432-072X
    Keywords: Purine fermentation ; Xanthine dehydrogenase ; Selenium ; Tungsten ; Molybdenum ; Clostridium acidiurici ; Clostridium cylindrosporum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The xanthine dehydrogenase of Clostridium acidiurici and C. cylindrosporum was assayed with methyl viologen as acceptor. In C. acidiurici the basal activity level was about 0.3 μmol/min x mg of protein. Cells grown on uric acid in the presence of 10-7 M selenite showed a 14-fold increase in xanthine dehydrogenase activity, which decreased with higher selenite concentrations (10-5 M). The supplementation with 10-7 M molybdate or tungstate was without effect. High concentrations of tungstate decreased the xanthine dehydrogenase if selenite was also present. In comparison, high concentrations of molybdate affected only a small decrease in activity level at the optimal concentration for selenite and relieved to some degree the inhibitory effect of 10-5 M selenite. With hypoxanthine and xanthine as substrates for growth again only the addition of selenite was necessary to show a similar increase in xanthine dehydrogenase activity. C. acidiurici could be grown in a mineral medium. Both xanthine dehydrogenase and formate dehydrogenase exhibited the highest level of activity if selenite and tungstate were present in that medium. In C. cylindrosporum the basal activity level of xanthine dehydrogenase was about 0.95 μmol/min x mg of protein. The addition of 10-7 M selenite to the growth medium increased the activity level about 3-fold, but the highest level (3.7 U/mg) was reached if 10-7 M molybdate was also added. The presence of tungstate resulted in a decreased enzyme activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00425064
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