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  • 1
    Electronic Resource
    Electronic Resource
    New emission spectra from oxygen (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 55 (1989), S. 2707-2708 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: New emission spectra have been observed from chemically produced excited oxygen. Evidence that the observed visible emission is due to oxygen dimer transitions is presented. Experimental results suggest that the observed oxygen dimer is stable O4 molecule rather than the usually observed Van der Waals-type dimolecular complex. The present system is discussed from the viewpoint of a new laser operating in the visible. The possibility of a similar oxygen-dimer laser operating in the near infrared is also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101931
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  • 2
    Electronic Resource
    Electronic Resource
    Observation of chemical laser oscillation in the visible range (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 2400-2401 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new visible chemical laser analogous to excimer lasers in lasing principle has been studied. Laser oscillation has been observed in the red spectral range. To our knowledge this is the first demonstration of chemical laser oscillation in the visible spectral range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101089
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  • 3
    Electronic Resource
    Electronic Resource
    Shape Memory Alloys (1988)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 18 (1988), S. 25-45 
    Details
    ISSN: 0084-6600
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ms.18.080188.000325
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  • 4
    Electronic Resource
    Electronic Resource
    Control of angiogenic activity in carcinogen-initiated and neoplastic hamster pouch keratinocytes and their hybrid cells (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 17 (1988), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study was undertaken to test the hypothesis that deregulated expression of the angiogenic phenotype by tumor cells is due to loss or inactivation of an angiogenesis suppressor gene(s). We used the technique of somatic cell hybridization to test the ability of untreated or chemical carcinogen-initiated hamster pouch keratinocytes, when fused to squamous epithelial neoplasms, to suppress tumor angiogenic activity by assaying hybrid-conditioned media (CM) in the avascular cornea of rat eyes. A non-angiogenic keratinocyte line, CL-2, derived from cultures of untreated epithelium and 3 lines of carcinogen-initiated keratinocytes, PN3, 5, and 7, of varying angiogenic potential were fused, using polyethylene glycol, to 3 tumorigenic, potently angiogenic, drug-resistant, hamster Serum-free 48-h CM from hybrid clones was prepared and assayed for angiogenic activity in rat corneas. CM from 5 hybrid clones derived from normal × neoplastic keratinocytes failed to induce an angiogenic response in 28 of 29 (97%) corneas tested. In contrast, CM from 4 hybrid clones derived from fusions between carcinogen-initiated and tumor cells were potently angiogenic in 24 of 25 (96%) corneas tested. Two angiogenesis suppressed hybrids clones were propagated in culture for an extended period of time, to permit chromosome segregation, and were found to re-express the angiogenic phenotype. These result indicate that angiogenesis is a recessive trait in normal hamster keratinocytes which is regulated in trans in these hybrid cells. It would also appear that loss or inactivation of angiogenesis suppressor function occurs early in the neoplastic process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1988.tb01328.x
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  • 5
    Electronic Resource
    Electronic Resource
    An adoptive immunotherapy of patients with medulloblastoma by lymphokine-activated killer cells (LAK) (1988)
    Springer
    Acta neurochirurgica 94 (1988), S. 47-52 
    Details
    ISSN: 0942-0940
    Keywords: Brain neoplasms ; medulloblastoma ; lymphokine-activated killer (LAK) cells ; adoptive immunotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An adoptive immunotherapy of 6 patients with medulloblastoma by lymphokine-activated killer (LAK) cells is described. They were from 2 to 9 years in age and had cerebrospinal fluid (CSF) dissemination of the tumours. All patients underwent the whole-neuraxis irradiation and chemotherapy. After the usual treatments, they were submitted to an adoptive transfer of one-haplotype identical LAK cells. The LAK cells were induced from peripheral blood lymphocytes (PBL) of their relatives with human recombinant interleukin-2 (rIL-2). 3–15×109 LAK cells were transferred intrathecally in 2–3 months. In 3 of 6 patients, neurological signs were improved and malignant cells had never been detected on CSF cytology after the adoptive immunotherapy. One among these 3 patients showed complete response in 20 months. Thus, this is an attractive approach for the treatment of medulloblastoma with CSF dissemination of the tumour which current therapeutic intervention can not cure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01406615
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  • 6
    Electronic Resource
    Electronic Resource
    Ontogeny of cholecystokinin-8 and glutamic acid decarboxylase in cerebral neocortex of macaque monkey (1989)
    Springer
    Experimental brain research 74 (1989), S. 249-255 
    Details
    ISSN: 1432-1106
    Keywords: Cholecystokinin-8 ; Glutamic acid de-carboxylase ; Cerebral cortex ; Primate ; Ontogeny
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Concentration of cholecystokinin-8 and the activity of glutamic acid decarboxylase were determined in the various cerebral cortical subdivisions of Japanese monkey (Macaca fuscata fuscata) at three different ages (embryonic 4 months, full-term and adult). The CCK-8 immunoreactive material extracted with 90% methanol from the cerebral cortex of the adult and foetal monkey were shown to be identical with synthetic cholecystokinin-8 by the criterion of co-elution on gel filtration chromatography (Sephadex G-50). The peptide concentration increased dramatically by about 30–80 fold (in terms of protein) and 17–28 fold (in terms of wet weight) between embryonic 4-month-old and full-term monkeys, while the level decreased 1/6–1/16 (protein) and 1/4–1/10 (wet weight) between full-term and adult monkeys. In adults, the highest levels of the peptide was observed in the association cortex, orbital prefrontal cortex and posterior parietal cortex. Glutamic acid decarboxylase activity, on the other hand, gradually increased about 4–10 fold (protein) between embryonic 4-month-old and adult animals and there was little variation in the increase rate among the cerebral subdivisions. In contrast to cholecystokinin-8, no reduction in the enzyme activity occurred between full-term and adult animals. The high level of cholecystokinin-8 in the embryonic period suggests that the peptide may participate in the regulation of the development of primate cerebral cortex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00248857
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  • 7
    Electronic Resource
    Electronic Resource
    Multiple associated endocrine abnormalities in a patient with pseudohypoparathyroidism type 1a (1988)
    Springer
    European journal of pediatrics 147 (1988), S. 536-538 
    Details
    ISSN: 1432-1076
    Keywords: Pseudohypoparathyroidism ; Hypothyroidism ; Neonatal mass screening ; Bone age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A girl with type 1a pseudohypoparathyroidism (PHP) presented several hormonal abnormalities. Although she had eluded neonatal thyroid screening, she was diagnosed as having hypothyroidism at the age of 5 months. Thereafter, a diagnosis of PHP was made on the basis of skeletal features of Albright osteodystrophy and lack of both cyclic adenosine monophosphate (c-AMP) and phosphaturic responses after parathyroid hormone (PTH) infusion. The basal levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were higher than normal and showed exaggerated responses to luteinizing hormone-releasing hormone (LH-RH). There was no growth hormone (GH) response to arginine infusion, and the prolactin (PRL) response after thyrotropin-releasing hormone (TRH) infusion was also impaired. The stimulating guanine nucleotide-binding protein (Ns) activity of the erythrocytes was reduced to 66.9%. The skeletal age was not delayed at the age of 5 months in spite of the hypothyroid state, and it advanced following thyroxine and vitamin D treatments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441985
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  • 8
    Electronic Resource
    Electronic Resource
    Surface kinetic aspects of Si incorporation in molecular beam epitaxial growth of GaAs (1989)
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 14 (1989), S. 619-622 
    Details
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The incorporation and amphoteric behavior of Si impurities in Si-doped (100) oriented molecular beam epitaxial (MBE) GaAs layers grown under different As4/Ga flux ratios but with a fixed Si flux have been studied using Hall effect measurements, photothermal ionization spectroscopy and photoluminescence. The Si donor concentration increases substantially with increasing As4/Ga flux ratio, while the Si acceptor concentration remains less than ∼ 1013 cm-3, regardless of the variation of As4/Ga flux ratio. The observed increase of carrier concentration with increasing V/III ratio is not due to a change of site preference of Si impurities from Ga to As sublattice sites as previously supposed, but is due to the increase in incorporation of Si donor. This result can be explained by the kinetic effects associated with surface reaction processes involved in Si impurity incorporation. From these results it is clear that the sticking coefficient of Si is less than unity, and varies with the growth conditions.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/sia.740141010
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  • 9
    Electronic Resource
    Electronic Resource
    Detection-threshold of 50-Hz electric fields by human subjects (1989)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 10 (1989), S. 319-327 
    Details
    ISSN: 0197-8462
    Keywords: hairy and hairless skin ; relative permittivity of hair ; AC electric field ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: The threshold intensity for detection of an AC electric field was studied in human subjects at several different temperatures and humidities. The dorsum and palm of the hand were exposed to fields, representing hairy and hairless skin, in order to clarify whether hair movement is critical for field detection. Experiments were carried out on human subjects (seven men and four women) during hot humid weather of July-August and dry cool air of October-November. Threshold values obtained in the summer were 30-65 kV/m for the hairy skin on the dorsum of the hand, while for the hairless skin on the palm the threshold was 〉 115 kV/m (highest field available due to limitations of the power supply). During the fall, the threshold was much higher than during the summer. We sought possible reasons for the difference and found that humidity was the main factor. Relative permittivity of woman's hair was then estimated by measuring capacitance of the hairs under dry (35% RH) and wet (85% RH) conditions at 20 °C. The values of relative permittivity obtained under these two conditions differed by several times the average. The differences in detection thresholds may be attributable to the different relative permittivities of the hairs under dry and wet conditions.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250100309
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