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  • 1
    ISSN: 1432-0584
    Keywords: AML in first CR ; ABMT ; BMT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the attempt to evaluate the role of Autologous and Allogeneic Bone Marrow Transplantation, we have retrospectively analyzed 159 patients with Acute Myeloid Leukemia in first complete remission treated in our Unit, most of whom were referred from other Institutions. High-dose therapy was uniform and consisted of cyclophosphamide 60 mg/kg/d on two consecutive days and TBI in a single dose (10 Gy) for ABMT patients and in fractionated doses (3.3 Gy × 3 days) for BMT patients. Eight years actuarial survival was similar in two groups (52% for BMT and 49% for ABMT). The actuarial risk of relapse for BMT and ABMT was 29% and 43%, respectively. Considering that none of ABMT patients was “purged” with in vitro technique, this review seems to confirm the importance of “in vivo” purging with postremission intensification, immediately before the harvesting. Of course, more patients and a longer follow-up are needed to drow final conclusions.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0584
    Keywords: CyA ; ABMT in hematological neoplasias ; GVHD
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the attempt to induce graft-vs-host disease (GVHD) in patients undergoing autologous bone marrow transplantation (ABMT) or blood stem cell transplantation (BSCT), 12 consecutive patients received cyclosporin A (CyA) post transplant. CyA was given at a dose of 1.5 mg/kg/day intravenously for 28 days, starting on the day of transplant. Histologically proven acute GVHD of the skin occurred in seven patients 9–14 days after ABMT and lasted 7–11 days. CyA-induced GVHD after ABMT resembles mild GVHD after allogeneic bone marrow transplantation (BMT). Although the preliminary data reported here show that it is possible to induce GVHD in patients undergoing ABMT, it is not yet known whether GVHD after ABMT will have an antitumor activity.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 3 (1972), S. 224-227 
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'auteur insiste sur le valeur pathogénétique des anomalies congénitales des arcs de l'atlas en cas de céphalées occipitales. Des 51 observations qui présentaient ces anomalies à l'examen radiographique du rachis cervical, le 50.9% accusait des céphalalgies. — Par contre, les autres malades se plaignaient d'une symptomatologie d'insuffisance vertébro-basilaire. Dans ces cas les anomalies de l'atlas sont responsables de troubles statiques et dynamiques du rachis cervical et d'une compression directe sur les artères du cou.
    Abstract: Zusammenfassung In dieser Arbeit wird die pathogenetische Bedeutung der leichten Entwicklungsanomalien verschiedener Segmente des Atlanten als Entstehungsursache eines typischen Kopfschmerzes hervorgehoben. Dieses Symptom war bei 50.9% der 51 Fälle vorhanden, die lediglich auf Grund roentgenologischer Befunde ausgesucht worden waren. Bei anderen Fällen verursacht die Knochenveränderung mittels statischer Störung der Gelenkdynamik der gesamten Halswirbelsäule, die sich auf die Arterien auswirkt, eine vertebro-basilare Insuffizienz.
    Notes: Summary The author emphasises the pathogenetic importance of slight anomalies of various elements of the first cervical vertebra in determining typical headache symptoms. — In 51 patients with such development anomalies chosen on the basis of X-ray findings this symptom is found present in 50.9 per cent of the cases. —In other cases the bone deformity, through changes in the articular statics and dynamics of the whole cervical spine, determines symptoms of vertebro-basilar insufficiency because of an effect on the vascular afferences.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 39 (1997), S. 639-641 
    ISSN: 1432-1920
    Keywords: Key words Magnetic resonance imaging ; Neurofibromatosis ; Brain neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a patient suffering from neurofibromatosis type 1 in whom neoplasms developed from the areas of altered signal which are generally considered benign and typical of the disease. MRI, despite two previous examinations 3 and 2 years before development of the tumour, gave no clue to an unfavourable outcome.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 6 (1973), S. 233-236 
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs décrivent deux cas de spasme hémifacial par compression sur le nerf du trait terminal de l'artère vertébrale. Un des deux patients présentait une malformation osseuse de la charniére atlo-occipitale et cette coincidence a permis des hypothèses pathogénetiques de type vasculaire en cas de spasme hémifacial dans porteurs de malformations osseuses de la charniére atlo-occipitale.
    Abstract: Zusammenfassung Die Autoren beschreiben 2 Fälle eines Spasmus facialis bei Kompression des N. VII durch das periphere Segment der A. vertebralis. Einer der beiden Patienten zeigte eine Knochenfehlbildung des atlantooccipital-Bogens. Durch dieses Zusammentreffen wird eine pathogenetische Hypothese der vaskulären Ursache in Fällen von Spasmus facialis bei Kranken mit Fehlbildungen der occipito-cervicalen Region angenommen.
    Notes: Summary The authors describe two cases of hemifacial spasm due to elongation of the terminal segment of the vertebral artery. One of the two patients had a bony malformation of the atlanto-occipital joint. This coincidence has indicated a vascular pathogenetic hypothesis in cases of hemifacial spasm with bone malformation of the atlanto-occipital joint.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1920
    Keywords: Megadolichovertebrobasilar anomaly ; neuro-vascular compression ; hemifacial spasm ; cranial nerve pathology ; cerebello-pontine angle syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have found numerous case reports, but no systematic study of the megadolichoverte-brobasilar anomaly (MDVBA). The purpose of this paper is to evaluate the relationships between arterial shifts of the vertebro-basilar system and neurological findings in the posterios fossa in our series of 132 cases. We found a high percentage (77.3%) of angiographic-clinical correlations having evaluated the arterial shifts, measured in mm, of the vertebro-basilar system in a frontal and a sagittal plane and concluded that the greater the degree of dislocation, the greater the number of positive cases. Nevertheless it is not possible to predetermine the presence of particular neurosymptomatology related to arterial dislocation degrees.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1920
    Keywords: Key words Klippel-Trenaunay syndrome ; Aneurysm, intracranial ; Oesophagus, duplication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Klippel-Trenaunay syndrome (KTS) is a congenital disorder resulting from a mesodermal abnormality, characterised by cutaneous capillary haemangiomas, hypertrophy of bone and soft tissues and varicose veins. The presence of intracranial aneurysms has rarely been described, while oesophageal duplication has not been reported previously. We describe a patient with the KTS with both there additional abnormalities, which could be explained by a postulated mosaic gene abnormality.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 15 (1978), S. 193-194 
    ISSN: 1432-1920
    Keywords: Vertebral artery ; Double fenestration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This is a case report of an angiographically demonstrated double fenestrtion of the extracranial vertebral artery found at the same level.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 22 (1982), S. 247-249 
    ISSN: 1432-1920
    Keywords: Metrizamide ; Iopamidolo ; Lumbar myelography complications
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nonionic water-soluble contrast medium, at first metrizamide and later Iopamidolo was used for lumbar myelography. Three serious neurological complications were noted: one case of total aphasia, one case of generalized seizures, and one of myoclonic jerking of the legs.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1920
    Keywords: Neurofibromatosis ; atlanto-occipital joint
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinical and radiological findings in a case of neurofibromatosis with congenital dislocation of dens of the axis are presented.
    Type of Medium: Electronic Resource
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