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  • 1995-1999  (23)
  • 1970-1974  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Application of 6 MeV/n heavy-ion beams to biophysical experiments (1996)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 67 (1996), S. 2000-2004 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new accelerator facility and two irradiation methods using 6 MeV/n heavy-ion beams are described along with preliminary results concerning their applications to biophysical investigations. The beams are obtained from the injector linac installed at the Heavy Ion Medical Accelerator in Chiba. Various ion species (He–Xe) having different charge states are accelerated to the same velocity, which is suitable for comparing the charge effects of heavy ions in the high linear energy transfer region. An attempt has been made to test the usefulness of the apparatus for studying track structure by using pBR322 plasmid DNA and spores as targets in vacuum. Newly constructed equipment with a molecular-beam source (water vapor) placed on this beam line is also described. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146958
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  • 2
    Electronic Resource
    Electronic Resource
    Prediction of Postoperative Left Ventricular Pump Function in Congenital Mitral Regurgitation (1999)
    Springer
    Pediatric cardiology 20 (1999), S. 418-421 
    Details
    ISSN: 1432-1971
    Keywords: Key words: Mitral regurgitation — Left ventricular function — Left ventricular afterload — Left ventricular wall stress — Mitral valve repair
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In adult patients with severe chronic mitral regurgitation, many predictors for estimating postoperative left ventricular systolic function have been proposed. However, none has been defined in children. We analyzed the relationship between such predictors and postoperative left ventricular fractional shortening in children with isolated congenital mitral regurgitation. Eight patients with isolated congenital mitral regurgitation were examined before and after surgery with echocardiography. Fractional shortening, left ventricular end-diastolic and end-systolic dimension indices, and left ventricular end-systolic wall stress/left ventricular end-systolic dimension index in the preoperative status were poorly correlated with postoperative left ventricular fractional shortening. Predictive wall stress, which was calculated from preoperative data of end-diastolic dimension, end-diastolic wall thickness, and diastolic blood pressure, correlated well with postoperative left ventricular fractional shortening (r=−0.90, p= 0.0024). It is important to consider not only myocardial contractility but also postoperative afterload for estimating postoperative left ventricular performance in chronic severe mitral regurgitation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002469900503
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Mercury levels and its chemical form in tissues and organs of seabirds (1996)
    Springer
    Archives of environmental contamination and toxicology 30 (1996), S. 259-266 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Liver, muscle, kidney, and feather samples from nine species of seabirds were analyzed for total and organic (methyl) mercury (MM). Total mercury (TM) levels in liver showed great intra- and inter-species variations, with the concentrations varied from 306 μg/g (dry weight) in black-footed albatross (Diomedea nigripes) to 4.9 μg/g in arctic tern (Sterna paradisaea), while MM levels were less relatively variable. The order of MM concentrations in tissues of all the seabirds except oldsquaw (Clangula hyemalis) was as follows: liver 〉 kidney 〉 muscle. The mean percentage of MM in total was 35%, 36%, and 66% in liver, kidney, and muscle, respectively, for all the species. Statistically significant negative correlations were found between the proportion of MM to TM and concentrations of TM in the liver and muscle of black-footed albatross and in the liver of laysan albatross. Furthermore, the percentage of MM decreased with an increase in TM concentrations in the liver, muscle, and kidney of all the species. Black-footed albatross had the highest concentration and burden of mercury in the liver, wherein more than 70% of the TM occurred as inorganic mercury. On the other hand, the mercury burdens in feathers were less than 10% of the body burdens, indicating that excretion of mercury by moulting is negligible. The results suggest that some seabirds are capable of demethylating MM in the tissues (mainly in liver), and store mercury as an immobilizable inorganic form in the liver. It is noteworthy that the species with a high degree of demethylation capacity and slow moulting pattern showed low mercury burdens in feathers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00215806
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  • 4
    Electronic Resource
    Electronic Resource
    Mercury Levels and its Chemical Form in Tissues and Organs of Seabirds (1996)
    Springer
    Archives of environmental contamination and toxicology 30 (1996), S. 259-266 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract. Liver, muscle, kidney, and feather samples from nine species of seabirds were analyzed for total and organic (methyl) mercury (MM). Total mercury (TM) levels in liver showed great intra- and inter-species variations, with the concentrations varied from 306 μg/g (dry weight) in black-footed albatross (Diomedea nigripes) to 4.9 μg/g in arctic tern (Sterna paradisaea), while MM levels were less relatively variable. The order of MM concentrations in tissues of all the seabirds except oldsquaw (Clangula hyemalis) was as follows: liver〉 kidney〉 muscle. The mean percentage of MM in total was 35%, 36%, and 66% in liver, kidney, and muscle, respectively, for all the species. Statistically significant negative correlations were found between the proportion of MM to TM and concentrations of TM in the liver and muscle of black-footed albatross and in the liver of laysan albatross. Furthermore, the percentage of MM decreased with an increase in TM concentrations in the liver, muscle, and kidney of all the species. Black-footed albatross had the highest concentration and burden of mercury in the liver, wherein more than 70% of the TM occurred as inorganic mercury. On the other hand, the mercury burdens in feathers were less than 10% of the body burdens, indicating that excretion of mercury by moulting is negligible. The results suggest that some seabirds are capable of demethylating MM in the tissues (mainly in liver), and store mercury as an immobilizable inorganic form in the liver. It is noteworthy that the species with a high degree of demethylation capacity and slow moulting pattern showed low mercury burdens in feathers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00215806
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    An X-ray pulsar with a superstrong magnetic field in the soft γ-ray repeater SGR1806 − 20 (1998)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 393 (1998), S. 235-237 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Soft γ-ray repeaters (SGRs) emit multiple, brief (∼0.1-s), intense outbursts of low-energy γ-rays. They are extremely rare—three are known in our Galaxy and one in the Large Magellanic Cloud. Two SGRs are associated with young supernova remnants (SNRs), and therefore most ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/30410
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  • 6
    Electronic Resource
    Electronic Resource
    Vaginal arteriovenous malformation: MR imaging (1996)
    Springer
    Abdominal imaging 21 (1996), S. 554-556 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Angiography—Arteriovenous malformation—Embolization—MRI—Vaginal tumor.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Vaginal arteriovenous malformations (AVMs), although rare, can lead to life-threatening complications. We report the first case of a vaginal AVM whose diagnosis and follow-up were performed by magnetic resonance imaging (MRI). MRI findings of the AVM are the blood flow-related features within the tumor, such as the phase-shift artifact, paradoxical enhancement, and flow voids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900126
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Dynamic MR imaging for extraserosal invasion of advanced gastric cancer (1997)
    Springer
    Abdominal imaging 22 (1997), S. 35 -40 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Stomach—Gastric cancer—Magnetic resonance imaging—Dynamic study, contrast media
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Dynamic magnetic resonance (MR) images in 37 patients with gastric cancers were obtained by a two-dimensional fast multiplanar spoiled gradient technique. The degree of tumor invasion was classified into four grades regarding a low-intensity band between the stomach and surrounding fat. Advanced gastric cancer was strongly enhanced, appearing as a thickened wall, by the contrast medium during the early to delayed phases of dynamic studies. The extent of invasion of the adjacent organs was diagnosed by the difference in enhancement between the tumor and the parenchyma. The sensitivity of extraserosal invasion was 93%. Dynamic MR diagnosis is useful for evaluating the extent of gastric carcinoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900134
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Small hepatic nodules in cirrhosis: ultrasonographic, CT, and MR imaging findings (1999)
    Springer
    Abdominal imaging 24 (1999), S. 47-55 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver, neoplasms—Liver, ultrasound—Liver, computed tomography—Liver, magnetic resonance—Comparative studies.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Purpose: The purpose of this study was to assess the imaging findings of pathologically-proved small hepatic nodules 2 cm in size or smaller detected with ultrasonography in cirrhotic patients with suspected hepatocellular carcinoma (HCC). Materials and Methods: We evaluated sonographically detected 32 small hepatic nodules which were pathologically confirmed in 23 consecutive cirrhotic patients who were suspected of having HCC. Twenty-six lesions were confirmed with ultrasonographically-guided aspiration needle-core biopsy, and six with definitive surgery. Ultrasonographic examination records were retrospectively reviewed. CT, and MR images obtained with various imaging techniques were retrospectively reviewed by two radiologists in a blind fashion. Results: The 32 hepatic nodules were comprised of seven focal fatty changes, two large regenerative nodules, three low-grade dysplastic nodules, five high-grade dysplastic nodules, and fifteen HCCs. Ultrasonography showed various echogenicity for the hepatic nodules. The signal-intensity characteristics with T1-weighted spin-echo, in-phase gradient-recalled-echo, and dynamic MR imagings may be useful in distinguishing HCC from nonHCC nodules. Conclusions: Nearly half of small hepatic nodules detected with ultrasonography were nonHCC nodules. Ultrasonographic findings may not be reliable in characterizing small hepatic nodules in cirrhosis. CT and MR imaging obtained with the various techniques are still insensitive to these hepatic nodules. RID=""ID=""〈e5〉Correspondence to:〈/e5〉 M. Kanematsu
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900439
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  • 9
    Electronic Resource
    Electronic Resource
    Ductal adenocarcinoma of the pancreas with intratumoral calcification (1999)
    Springer
    Abdominal imaging 24 (1999), S. 610-613 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Pancreas—calcification—Neoplasms—Adenocarcinoma—Computed tomography (CT)—Helical.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present two cases of ductal adenocarcinoma of the pancreas with intratumoral calcification. The two cases indicate two different etiologies for intratumoral calcification in ductal adenocarcinoma. Thus, the possibility of adenocarcinoma should be considered when a tumor with intratumoral calcification is found, although the incidence of intratumoral calcification in the ductal adenocarcinoma of the pancreas remains rare.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900574
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  • 10
    Electronic Resource
    Electronic Resource
    Ovarian hormone-induced beta-cell hypertrophy contributes to the homeostatic control of beta-cell mass in OLETF female rat, a model of Type II diabetes (1998)
    Springer
    Diabetologia 41 (1998), S. 799-805 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Ovarian hormones ; beta-cell ; hypertrophy ; pancreatectomy ; OLETF rat.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A sexual dimorphism regarding the incidence of diabetes mellitus in OLETF rat, a model of Type II diabetes, has been reported. As a result, the effects of ovarian hormones on beta cells per se was examined by comparing the capacity of beta-cell proliferation and changes in blood glucose and plasma insulin concentrations after a 70 % pancreatectomy. All female animals were randomly assigned to two protocols. The rats involved in protocol I received either a 70 % pancreatectomy (Px) or a sham pancreatectomy (sham) at 6 weeks of age, along with their diabetes-resistant counterparts, female LETO rats, which served as normal controls. The rats belonging to protocol II were given an ovariectomy (Ox) at 5 weeks of age, and one week later, they were subjected to either Px or the sham operation, with/without hormone (estradiol, 50 μg/kg; testosterone, 1 mg/kg) replacement. The findings indicate that the capacity for compensatory growth of beta cells after Px was affected by both sex hormonal and genetic components, since a 70 % Px resulted in sustained hyperglycaemia within the first week after surgery, but was ameliorated by an increase in beta-cell mass thereafter in the non-Ox Px OLETF rats. The Ox also caused a decline in beta-cell mass which could be improved by replacement with ovarian hormones. Not only endogenous but also replacement ovarian hormones, led to a beneficial effect on beta cells per se in OLETF female rats. This was reflected by an increased beta-cell mass accompanied by a parallel increase in plasma immunoreactive insulin concentration. The effects of ovarian hormones, however, contributed to the beta-cell hypertrophy rather than expansion of the beta-cell population to achieve glucose homeostasis, as evidenced by an increased area of individual beta-cell after Px rather than an increased BrdU-labelling index for the beta cells. The present study suggests that ovarian hormone-induced beta-cell hypertrophy may typically occur, to compensate for changes in functional demand as the results of a 70 % Px in female OLETF rats. [Diabetologia (1998) 41: 799–805]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050990
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