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  • 1
    Electronic Resource
    Electronic Resource
    Edge plasma density reconstruction for fast monoenergetic lithium beam probing (1993)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 64 (1993), S. 1699-1704 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Two different electron density reconstruction methods for 8-keV neutral lithium beam probing have been developed for the Compact Helical System (CHS). Density dependences on emission and ionization processes are included by using effective rate coefficients obtained from the collisional radiative model. Since the two methods differ in the way the local beam density in the plasma is determined, the methods have different applicable electron densities. The beam attenuation is calculated by iteration from the electron density profile in method I. In method II, the beam remainder at the observation point z is determined by integrating the Li i emission intensity from z toward the position of emission tail-off. At the emission tail-off, the fast lithium beam is completely attenuated. Selecting an appropriate method enables us to obtain edge electron density profile well inside the last closed flux surface for various ranges of plasma densities (1012–5×1013 cm−3). The electron density profiles reconstructed by these two different methods are in good agreement with each other and are consistent with results from ruby laser Thomson scattering.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1143996
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  • 2
    Electronic Resource
    Electronic Resource
    Inductively driven gas-breakdown plasma source for intense ion beam production (1993)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 64 (1993), S. 2737-2745 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A plasma source based on an inductive breakdown of a supersonic gas puff is described. The source was developed to provide an anode plasma for an annular, extraction geometry, magnetically insulated ion diode. In this source, plasmas with densities of 1013 cm−3 were generated and accelerated to velocities of 20–30 cm/μs; plasma fluxes of 10–40 A/cm2 were obtained. Operating the source under the diode insulating field effect, plasma fluxes above 100 A/cm2 were observed. When the plasma source was used in conjunction with a magnetically insulated diode gap, intense ion beams with proton fluxes of more than 100 A/cm2, energies of 100 keV, and beam pulses longer than 1 μs were extracted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1144412
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  • 3
    Electronic Resource
    Electronic Resource
    Molecular Cloning of Novel Small GTP-Binding Proteins in Rat Liver (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 707 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb38118.x
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  • 4
    Electronic Resource
    Electronic Resource
    Association of EGF receptor expression with proliferating cells and of ras p21 expression with differentiating cells in various skin tumours (1990)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 123 (1990), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The localization of DNA replicating cells, epidermal growth factor (EGF) receptor-expressing cells and ras oncogene product p21 (p-21ras) positive cells were examined in various skin tumours to elucidate the role of EGF receptor and p21ras in the epidermis. Normal skin, keratoacanthoma (KA), solar keratosis (SK), Bowen's disease (BD), squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and extramammary Paget's disease (PD) were studied. EGF receptors were seen in proliferating layers, where DNA replicating cells localize, but p21ras was found in the more differentiated layers. We conclude that EGF receptor expression is closely associated with cellular proliferation, but p21ras may play a role in the differentiation of cells in various skin tumours.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1990.tb01823.x
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  • 5
    Electronic Resource
    Electronic Resource
    Stable and strong expression of basic fibroblast growth factor in naevus cell naevus contrasts with aberrant expression in melanoma (1994)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 130 (1994), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary It has been proposed that basic fibroblast growth factor (bFGF) is an autocrine growth factor of melanoma cells, in contrast with normal melanocytes where bFGF acts as a paracrine growth factor. As this notion is mostly based on the different requirements for bFGF in cultures of benign and malignant pigment cells in vitro, we performed an immunohistochemical study to examine bFGF expression in vivo using paraffin sections from naevus cell naevi (NCN) and malignant melanoma (MM). All the NCN (n=7) showed strong and homogeneous expression of bFGF protein, whereas the primary MMs (n=5) showed heterogeneous expression, with a population of negative cells. Metastatic MMs (n=5) also showed heterogeneous expression, and had a greater population of negative cells. These results suggest that bFGF has some, as yet unidentitied, role in the growth of benign NCN, and that overexpression of bFGF is neither a prerequisite for melanoma genesis nor for progression to metastatic MM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1994.tb02927.x
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  • 6
    Electronic Resource
    Electronic Resource
    Plane elastic solution for the second mixed boundary value problem and its application (1994)
    Springer
    Archive of applied mechanics 64 (1994), S. 295-306 
    Details
    ISSN: 1432-0681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Übersicht Die Lösung des zweiten gemischten Randwertproblems der ebenen Elastizität mit zwei kraftbeanspruchten und zwei gestützten Rändern wird dargestellt. Für die Analyse wird eine rationale Abbildung verwendet, die als Summe partieller Lösungen aus komplexen Spannungsfunktionen aufgebaut ist. Für gleichmäßige Zug- und Schubbeanspruchungen kann die Lösung in geschlossener Form dargestellt werden und ist verwendbar in Rißaufgaben der linear elastischen Bruchmechanik. Als Illustration der allgemeinen Lösung dient ein verzweigter Bereich der gegenseitigen Einwirkung einer quadratischen Öffnung mit Seitenkerbe und eines Risses. Die Spannungsverteilungen und Spannungsintensitäten werden dabei berechnet.
    Notes: Summary A solution is obtained for the second mixed boundary value problem with two boundaries loaded with external forces, and the other two boundaries simply supported. A rational mapping function formed as a sum of fractional expressions and complex stress functions is used for the analysis. A closed form solution can be obtained under uniform tensile and shearing loadings. These solutions are applicable to crack problems in linear elastic fracture mechanics. In order to illustrate the general solution, a double connected region is considered, in which interaction between a square hole with a crack extension and another crack is investigated. Stress distributions and stress intensity factors are obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00788215
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  • 7
    Electronic Resource
    Electronic Resource
    Characterization of a temperature-sensitive mutant in the RNA polymerase PB2 subunit gene of influenza A/WSN/33 virus (1990)
    Springer
    Archives of virology 114 (1990), S. 65-73 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The temperature-sensitive mutant ts-1 of influenza virus A/WSN/33 carries mutations in the gene encoding RNA polymerase PB2 subunit. Effect of temperature on various steps of viral RNA synthesis was examined using disrupted virions of ts-1 mutant. The initiation of RNA synthesis with dinucleotide ApG primer was not affected by elevated temperature, whereas that with primer RNA containing 5′-terminal cap-1 structure was temperature-sensitive. The result supports the previous notion deduced from the UV-crosslinking experiments, that PB2 is involved in the cap-1 dependent initiation of RNA synthesis. In addition, the ts-1 mutant showed a defect in RNA chain elongation. Nucleotide sequence analysis of RNA segment 1 of ts-1 mutant revealed that the amino acid number 417 is essential for the recognition of cap-1 structures and/or the interaction with catalytic unit of the RNA polymerase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01311012
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of dietary calcium, magnesium and phosphorus on the formation of struvite stones in the urinary tract of rats (1991)
    Springer
    Urological research 19 (1991), S. 305-308 
    Details
    ISSN: 1434-0879
    Keywords: Diet ; Calcium ; Magnesium ; Phosphorus ; Struvite stones ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary After feeding various diets we studied the effects of dietary calcium, magnesium and phosphorus on the formation of struvite stones in rats with urinary tract infections, and also studied the effects of the administration of vitamin D3 and aluminium gel on stone formation. A low-magnesium diet decreased urinary magnesium and prevented stone formation, but a medium-calcium diet did not significantly decrease stone weight. A high-calcium diet decreased urinary phosphorus and inhibited stone formation. A high-calcium and high-phosphorus diet decreased urinary excretion of magnesium and inhibited stone formation. Although the administration of vitamin D3 did not inhibit stone formation, aluminium gel decreased the urinary level of phosphorus and prevented stone formation. A marked decrease in urinary magnesium and/or phosphorus may prevent struvite stone formation in rats with urinary tract infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00299065
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  • 9
    Electronic Resource
    Electronic Resource
    Thermal calculation of the hot rolling process of sheet aluminium (1992)
    Springer
    Archive of applied mechanics 62 (1992), S. 435-446 
    Details
    ISSN: 1432-0681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Übersicht Vorgestellt wird ein numerisches Modell zur Ermittlung der Walzguttemperatur in einer Warmbandstraße für Aluminium, das auf einfachen theoretischen Grundannahmen beruht. Mit dem Modell wird die Möglichkeit der Produktivitätssteigerung durch eine veränderte Gestaltung der Fertigstraße unter dem Gesichtspunkt der Steuerung der Walzguttemperatur untersucht. Die Ergebnisse zeigen, daß die Erhöhung der Anzahl der Fertiggerüste einen positiven Einfluß auf die Produktivität hat.
    Notes: Summary In order to predict the material temperature throughout the hot rolling process of aluminium, a numerical model is proposed in a theoretical as well as simple way. Using the model, the possibility of the improvement in productivity by reforming the finishing mill arrangement is examined under aspect of the control of material temperature. The results so obtained show the positive effect of increasing the number of finishing mills on the productivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00810234
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  • 10
    Electronic Resource
    Electronic Resource
    1-2B7B: Monoclonal antibody reacting to the 120 kDa polypeptide component of human epidermal hemidesmosomes (1991)
    Springer
    Archives of dermatological research 283 (1991), S. 310-316 
    Details
    ISSN: 1432-069X
    Keywords: 1-2B7B monoclonal antibody ; Hemidesmosome ; Epidermal-dermal junction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Immunohistochemical and immunochemical analyses were performed on a monoclonal antibody designated 1-2B7B which was derived from immunizing mice with human prostate epithelial tissue. The 1-2B7B antigen was expressed not only along the acinous basement membrane zone (BMZ) of the prostate and testis, but also along the BMZ of the epithelia of several other organs including the skin, oesophagus, urinary bladder, ureter, stomach, intestine and bile duct. The antigenic epitope was not expressed in these tissues of lower mammals. Immunoelectron microscopic studies on normal human skin revealed that the 1-2B7B antigen was localized mainly just beneath the hemidesmosomes of basal keratinocytes, but not beneath melanocytes. Indirect immunofluorescence and immunoelectron microscopic studies on 1 M NaCl-split skin confirmed that this antigen was not separated from the cytoplasmic membrane of basal cells after salt treatment. SDS polyacrylamide gel electrophoresis of immunochemically purified protein from the epidermis demonstrated the molecular weight of the antigen to be 120 kDa. 1-2B7B monoclonal antibody should be a useful probe for studying the pathomechanism of some blistering diseases, as well as the assembly and function of the epidermal-dermal junction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00376619
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