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  • 1
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Periarteritis nodosa ; Magnetic resonance imaging ; Cerebral lesions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The course is reported of a patient with periarteritis nodosa who initially presented with neurological symptoms. Multiple cerebral lesions were documented by the first magnetic resonance imaging (MRI) investigation. The majority of these had disappeared completely in the follow-up MRI studies. In contrast to neurological improvement the patient eventually died due to multiorgan failure. Postmortem histological examination revealed no pathological findings in the brain except one single necrotic area already known from MRI. Remissions of histological and angiographic alterations in periarteritis nodosa have been described as “local healing” leading to fibrosis and scarring. Our findings suggest that restitutio ad integrum may occur, at least in cerebral lesions.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 26 (1976), S. 1-17 
    ISSN: 1432-1106
    Keywords: Medial geniculate body ; Neuronal geometry ; Synaptic triplets ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Golgi and electron microscopic analysis of the known cellular layers in concentric shells of the ventro-lateral portion of the medial geniculate body revealed a flat grid of high density neuropil filling the space between the geniculocortical relay cells, forming essentially a single cell layer in each lamina. The “skeleton” of this neuropil grid is made up by the interdigitating dendritic tufts of the geniculocortical relay cells, joined together by a rich system of desmosomoid adhesion plaques. The “holes” of the “skeleton” are filled in by the multilobed dendritic appendages of Golgi type II interneurons and the grape-like terminals of the inferior collicular specific afferents. Additional axon terminals of other sources — terminals of descending corticogenicular fibers, axons of the Golgi type II interneurons and terminals of the initial collaterals of the geniculocortical relay cells — contribute only to a very insignificant fraction of neuropil volume. The Golgi type II interneurons are oriented in perpendicular direction to the cell layers so that they may bridge with their dendrites several successive layers. Although the general expression “synaptic glomeruli” used in other relay nuclei for this type of specific synaptic arrangement is hardly applicable to this grid-like neuropil, the essential synaptic articulation pattern of all thalamic relay nuclei is well maintained. The specific inferior collicular afferents are presynaptic to both relay cell dendrites and to the multilobed dendritic appendages of Golgi type II cells, which in turn are presynaptic to the same dendritic regions of the relay cells receiving the bulk of the specific afferents.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    HNO 45 (1997), S. 424-424 
    ISSN: 1433-0458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: In Heft HNO 5/97 erschien bereits der erste Teil (Überblick der geschichtlichen Entwicklung. Die zwei weiteren Beiträge folgen in den nächsten Heften. Dieses Editorial hat unter anderem den Zweck, den Leser auf die Folge dieser Beiträge aufmerksam zu machen, die zwar getrennt als vier einzelne Originalarbeiten erscheinen, im Grunde aber eine Einheit bilden.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-2307
    Keywords: Cellular immune system ; Liver ; Blood ; Lewis lung carcinoma ; Liver metastases ; Tumour necrosis factor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated the reaction of the cellular immune system of liver and blood in the C57BL/6 mouse to a metastasizing Lewis lung carcinoma. The cellular immune system of the liver consists of mature and immature macrophages, B-cells, T-cells including their subpopulations, and natural killer cells, and their percentage frequencies differ significantly from those in the corresponding mononuclear blood cell (MBC) compartment. This suggests that the hepatic immune cells represent a system with autonomous function showing a typical homing of its members. Imminent metastasis to the liver is signalled by impressive alterations in the percentage frequencies of nonparenchymal liver cells (NPLC). There are a dramatic loss of mature macrophages, an increase in immature macrophages, a reduction of T-helper cells leading to a low CD4/CD8 ratio, and an increase in natural killer cells. In the blood, the corresponding precursor cells show comparable changes with a delay of at least 2 days. Early metastasis is accompanied by a significant increase in mononuclear NPLC producing tumour necrosis factor α. The alterations in percentage frequencies of the NPLC during tumour metastasis differ markedly from the changes in these cells in the liver during endotoxinaemia.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary In the turbidimetric determination of traces of phosphoric acid, in accord with the Hegedüs and Dvorszky version, employing strychnine nitrate, excellent reproducibility is attained only when the MoO3 employed for the preparation of the reagent contains 0.2–0.5% WO3/MoO3. If less than 0.01% WO3/MoO3 is present, large deviations in the obtained values ensue.
    Notes: Zusammenfassung Mit der turbidimetrischen Strychninnitrat-Methode für Phosphorspurenbestimmung nach der Version von Hegedüs und Dvorszky kann man nur dann ausgezeichnete Reproduzierbarkeit erreichen, wenn das für die Reagenszubereitung verwendete MoO3 0,2–0,5% WO3/MoO3 enthält. Falls weniger als 0,01% WO3/ MoO3 anwesend sind, kommt es zu starken Meßwertschwankungen.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The analytical methods, which give information directly or at least at a speed corresponding to the technology about the momentary composition of the steel bath, are indispensable for the optimization of the metallurgical processes. Especially the determination of oxygen concentration plays a very important role among the socalled quick analytical methods. The sources of reoxidation have the most serious pernicious effect, because the oxygen level of steel increases again for the effect of reoxidation after the deoxidation. The determination of oxygen content of the samples taken from the steel bath by means of classical method is not suitable for controlling the metallurgical processes, because the time necessary for the traditional analytical methods is unfavourably long and they measure the total oxygen content of the steel bath. It is, however, more important to know the so-called disposable oxygen concentration, for controlling the metallurgical reactions. The principle of determining the active oxygen content is the measurement of the electromotive force of the solid ZrO2 electrolyte cell. The possibility of the direct measurement of active oxygen content seems to be a “milestone” in adjusting the oxygen level of the metallurgical processes, and by this influencing favourable the morphology of the nonmetallic inclusions of steel to improve the quality of steel. The quantity of Al necessary theoretically for the final deoxidation, if the oxygen level is known, is not enough, but it is important to know the quantity of the dissolved Al, too. Therefore, it became necessary to work out such methods which determine the Al content after a very quick dissolution by means of atomic absorption spectrometry, or photometry and the period of determination is some minutes only. The development of the inclusion–separation methods is considered also very important, because it completes the analytical examinations controlling and following the steelmaking technology with valuable data.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0584
    Keywords: Key words Centrifugal elutriation ; Mean corpuscular volume ; Glycosylated hemoglobin ; Reticulocyte count ; Red cell age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The present study was designed to determine the effect of anisocytosis on the association of MCV values with HbA1c and reticulocyte counts as markers of red cell age. Normo-, micro- and macrocytic samples, fractionated by counterflow centrifugal elutriation were studied. The previously described correlation between MCV and HbA1c was only observed in normal samples and in the middle fractions of samples with anisocytosis. At both extremes of the elutriation profile, curves for HbA1c content and reticulocyte count levelled out. Furthermore, in fractions containing the largest red cells of the microcytic series and the smallest red cells of normo- and macrocytic samples, reticulocyte count decreased while HbA1c content increased with increasing MCV. From these data it is concluded that MCV is not an absolute determinant of red cell age in case of anisocytosis.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The sequential application of the avidin-biotinperoxidase complex technique was used to localize multiple tissue antigens on a single free floating section of rat brain. sequential visualization of individual antigens was achieved by the silver-gold-intensified diaminobenzidine (DAB) in the first step, nickel-intensified DAB in the second step, and the DAB alone in the third step of the immunostain procedure. For the demonstration of this method, tyrosine hydroxylase (TH), corticotropin-releasing factor (CRF), and vasopressin (VAS) antisera were used. Sections from the hypothalamic paraventricular nucleus (PVN) of rats pretreated with colchicine were stained. Black TH containing cell bodies were clearly distinguished from blue stained CRF cells and from yellow stained VAS-containing cell bodies in the PVN on the 25–30 μm thick vibratome sections. The sequential immunostaining procedure presented here results in superior staining of multiple antigens as compared to that achieved by the sequential application of the peroxidase-antiperoxidase (PAP) technique.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 26 (1976), S. 19-37 
    ISSN: 1432-1106
    Keywords: Medial geniculate body ; Interneurons ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three different types of interneurons can be separated in the Golgi picture, and many of their details can be identified under the electron microscope, in the medial geniculate body (MGB) of the cat: (1) typical short axon Golgi II. cells of the thalamic type, (2) somewhat larger Golgi type II cells with medium range axon, and (3) spidery neurogliform short axon cells. The most distinctive features of the two first types (1) and (2) are their irregular drumstick shape appendages, increasing in number as well as in length and irregularity of their stalks towards the periphery of the dendrites. These appendages form the vast majority of synaptic profiles in the aggregations of synaptic neuropil (glomeruli) of the nuclei, and they are both presynaptic and postsynaptic by the usual standards applied for the evaluation of the polarity of synapses. The characteristic beaded dendrites of the (3) neurogliform cell type can be recognised particularly easily in the electron microscope picture. They are both presynaptic and postsynaptic in structural polarity. All identified process profiles of interneurons contain flattened (F.-type) or pleomorphic synaptic vesicles. Membrane contacts, in which the interneurons appear to be presynaptic are either of the symmetric (Gray type II) or of an intermediate type. The membrane contacts of postsynaptic portions of the interneurons are usually of the asymmetric type (Gray type I) and the presynaptic profiles contain round (R-type) vesicles. The larger one have been shown already earlier to be derived from specific sensory (inferior collicular) afferents, while many of the smaller ones could be identified in the present study as being derived from cortico-geniculate descending pathways, arising from the auditory areas. Some of the synaptic contacts of the interneurons are apparently derived from other interneurons, the presynaptic profiles being often equivocal or more likely of axonal origin (all interneurons have clear axons in the Golgi picture). The occurrence of three distinct types of interneurons — probably all of inhibitory nature — the complexity in synaptic arrangement, and more particularly in the dendritic linkage of numerous synaptic sites does not favour such simple explanations as surround inhibition by forward or by backward inhibition, but suggests more sophisticated modes of impulse processing in the MGB.
    Type of Medium: Electronic Resource
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