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  • 1
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Responses of stomatal conductance (gs) to increasing vapour pressure deficit (D) generally follow an exponential decrease described equally well by several empirical functions. However, the magnitude of the decrease – the stomatal sensitivity – varies considerably both within and between species. Here we analysed data from a variety of sources employing both porometric and sap flux estimates of gs to evaluate the hypothesis that stomatal sensitivity is proportional to the magnitude of gs at low D (≤ 1 kPa). To test this relationship we used the function gs=gsref–m· lnD where m is the stomatal sensitivity and gsref=gs at D= 1 kPa. Regardless of species or methodology, m was highly correlated with gsref (average r2= 0·75) with a slope of approximately 0·6. We demonstrate that this empirical slope is consistent with the theoretical slope derived from a simple hydraulic model that assumes stomatal regulation of leaf water potential. The theoretical slope is robust to deviations from underlying assumptions and variation in model parameters. The relationships within and among species are close to theoretical predictions, regardless of whether the analysis is based on porometric measurements of gs in relation to leaf-surface D (Ds), or on sap flux-based stomatal conductance of whole trees (GSi), or stand-level stomatal conductance (GS) in relation to D. Thus, individuals, species, and stands with high stomatal conductance at low D show a greater sensitivity to D, as required by the role of stomata in regulating leaf water potential.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1569-8041
    Keywords: neuroblastoma ; prognosis ; telomerase activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Treatment of neuroblastoma has remained a major challenge in pediatric oncology because the assessment of the individual prognosis, particularly in disseminated disease is still obscure. Previous studies have correlated clinical outcome with activity levels of telomerase, a cellular reverse transcriptase which has been detected in the majority of human malignant tumors. Patients and methods: In this blind-trial study, a non-radioactive telomeric repeat amplification protocol (TRAP) with an internal telomerase-assay standard was used on an automated laser fluorescence sequencer for the detection and semiquantitative analysis of telomerase activity (TA) in 67 neuroblastomas of all clinical stages from the German Neuroblastoma Trial and 2 ganglioneuromas. TA levels were correlated with event-free and overall survival rates and established prognostic markers such as MYCN. Results: TA was present in 14 of 69 (20%) samples, including 3 of 22 stage IVS, 8 of 14 stage IV, 1 of 10 stage III, 1 of 7 stage II and 1 of 14 stage I neuroblastomas and 0 of 2 ganglioneuromas. We found a strong statistical correlation between the presence of TA and poor clinical prognosis with regard to all tumor stages. Multivariate analysis revealed TA as an independent prognostic marker. In particular, the analysis of TA in IVS neuroblastomas distinguished two different prognostic groups. Conclusions: Our data suggest that TA is an independent prognostic marker in neuroblastoma which, in combination with other markers such as MYCN, may proof useful in assessing the individual patient's prognosis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 64 (1986), S. 89-91 
    ISSN: 1432-1440
    Keywords: 1,25-Dihydroxyvitamin D3 ; Hodgkins's disease ; Parathyroid hormone ; Hypercalcemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 74-year-old woman was hospitalized because of decreased appetite, fatigue, and weight loss. The laboratory examination revealed hypercalcemia, a slightly increased serum creatinine level, and a markedly elevated serum level of 1,25-dihydroxyvitamin D3. The most important finding the physical examination revealed was enlarged inguinal lymph nodes. A biopsy disclosed lymphocyte-depleted Hodgkin's disease. After steroids, but not after calcitonin, both the elevated calcitriol concentration and serum calcium normalized. In spite of intensive chemotherapy, a further episode with hypercalcemia occurred and increased 1,25-dihydroxyvitamin D3 serum levels were observed. According to the available evidence it seems probable that the humoral hypercalcemia in this patient resulted from production of 1,25-dihydroxyvitamin D3 in the tumor.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 67 (1989), S. 308-312 
    ISSN: 1432-1440
    Keywords: Hypouricemia ; Uric acid nephropathy ; Tubular urate secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This report is about a 23-year-old man who required hemodialysis in connection with an acute renal failure resulting from uric acid nephropathy without hyperuricemia. After recovering renal function he showed extreme hypouricemia (0,1–0,3 mg/dl) and elevated uric acid clearance (100–300 ml/min). The fractional excretion of uric acid (Cua/Cer) could be suppressed by oral pyrazinamide and enhanced by probenecid. As no other renal tubular or metabolic abnormalities were detected, it is suggested that a markedly increased renal tubular urate secretion was responsible for the hypouricemia and also for the rare side-effect of an uric acid nephropathy in this patient.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 61 (1995), S. 249-251 
    ISSN: 1432-0649
    Keywords: 42.68 ; 42.30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The combination of remote sensing methods like Doppler lidar and FTIR offers the possibility to determine mass fluxes of gases remotely. Doppler lidar measures the three-dimensional wind vector in the vicinity of diffuse sources or the velocity of air in a chimney plume if an industrial complex is monitored. FTIR is a multi-component remote sensing method for gas concentrations. The Fourier transformation of an interferogram of a Michelson interferometer within a FTIR system converts the recorded intensity (function of optical path length) to a spectral signal (function of wavenumber). Both information, velocity and concentration, give the mass fluxes of the tracer (gas). A first test was performed at Munich-North power station with FTIR and cw-Doppler lidar. Fluxes of CO2, CO, NO, and HC1 were determined. The results are in good agreement with the fluxes measured by in-situ instruments of the power station. The method can be used to control industrial complexes from an outside observation site.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 68 (1999), S. 321-324 
    ISSN: 1432-0630
    Keywords: PACS: 42.70; 66.30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: 3 by diffusion doping is investigated by means of secondary neutral mass spectrometry and secondary ion mass spectrometry. The diffusion of praseodymium in LiNbO3 can be described by Fick’s laws of diffusion with a concentration-independent diffusion coefficient and a limited solubility of praseodymium in LiNbO3 increasing exponentially with rising temperature. The diffusion depends on the Li2O content of the LiNbO3 crystal. For LiNbO3 crystals with a nominal slight difference in the congruent composition, the diffusion constants and activation energies for Z-cut LiNbO3 are 3.28×10-5 cm2/s and 2.27 eV, and 1.39×10-5 cm2/s and 2.24 eV, respectively. Titanium-doped waveguides are formed in Pr:LiNbO3 and characterised in relation to waveguide loss and absorption in the visible and near infrared.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Contributions to mineralogy and petrology 95 (1987), S. 182-190 
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Lamellar nigerite is found in Zn-rich spinel from a sample that contains chiefly anthophyllite + spinel + cordierite, lesser amounts of quartz and chlorite, as well as sphalerite, pyrite, pyrrhotite, and galena, and rare cassiterite and rutile. Nigerite can be described as interlayering of spinel-like (R2+Al2O4) and nolanite-like ((Sn, Ti)Al4O8) structures. In nigerite, the spinel-like part is also compositionally related to spinel, but in the nolanite-like part only the structural analogy exists. Stoichiometric assumptions that relate the anhydrous cation sum to the amount of R4+ cations present, allow Fe3+ estimates from microprobe analyses, and a representative analysis gives the following anhydrous formula: Mg1.30Fe 0.65 2+ Zn3.03Mn0.03Al11.65Fe 0.35 3+ Sn0.32Ti0.18O24. The nigerite is Zn-rich with a Zn ratio (Zn/(Zn+Mg+ Fe2+)) of about 0.59, and the Sn ratio (Sn/(Sn+Ti)) that ranges from about 0.63 to 0.41. The Fe3+ content in these samples ranges from 0.35 to 0.52 (24 oxygen basis). Textures suggest that the nigerite could have formed by the breakdown of R 2 2+ (Sn, Ti)O4 and R2+Al2O4 spinel components during more complex reactions. An experimental investigation of the MgAl2O4-Mg2SnO4 join indicates that the solubility of Mg2SnO4 component in spinel over the T interval 500 to 900° C is about 0.5 to 3.0 mole %. This, coupled with the increased solubility expected from the presence of Ti, gives good agreement with the 2.4 to 2.6 mole % R 2 2+ (Sn, Ti)O4 component in spinel that is estimated to be the maximum necessary to form the compositions and amounts of observed nigerite.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 63 (1985), S. 217-220 
    ISSN: 1432-1440
    Keywords: Vegetarians ; Acute protein load ; Renal function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In normal man an acute protein load increases the glomerular filtration rate (GFR) significantly, which seems to represent a renal functional reserve. Healthy vegetarians are known to have a statistically reduced baseline GFR. We performed three creatinine clearance studies (24-h study design) on each of nine healthy vegetarian subjects. Th first clearance was measured as baseline, the second one was done on day 2 after an oral protein load of 100 g vegetarian protein (1.2–2.0 g/kg body wt.), respectively, ingested within half an hour. The third clearance, serving as a control, was done on day 14. All subjects had their normal vegetarian meals during the study. All vegetarians had at all times a normal serum creatinine level. The mean baseline creatinine clearance was 65.4±33.3 ml/min. 1.73 m2. In five of nine vegetarians we found a significant increase of the creatinine clearance after the protein load of 66.0% (mean) and a decrease to the baseline values, respectively, when the control clearance was measured. The remaining four vegetarians did not increase their creatinine clearance immediately after the protein challenge and their control clearances were found to be significantly reduced (−40.2%) compared to the individual baseline.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 64 (1986), S. 621-622 
    ISSN: 1432-1440
    Keywords: Hemodialysis ; HTLV-III ; AIDS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An investigation for HTLV-III antibodies in chronic hemodialysis patients revealed in four out of 276 patients a positive result using the ELISA and western blot techniques. All HTLV-III positive patients had received blood transfusions. As it has been shown that a needle stick could transmit the HTLV-III, it is suggested that hemodialysis patients who have received frequent blood transfusions should be screened.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1437-9813
    Keywords: Key words Mechanical ileus ; Small-bowel atresia ; Meconium ileus ; Intestinal feeding ; Short-bowel syndrome ; Extracorporeal stool transport
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Between May 1994 and June 1995, nine newborns underwent surgery due to mechanical ileus or intrauterine perforation of the small bowel. Three were very-low-birth-weight infants weighing between 520 and 1,200 g. Surgery was performed in the first 2 days of life and split ileo- or jejunostomas were implanted. Early oral nutrition was initiated. To avoid non-use of the distal bowel and short-bowel syndrome, the aboral stoma was irrigated a few days later with the proximal feces. A new technique was applied to transport the chyle continuously from the oral to the aboral stoma: the stool was collected in an especially constructed stoma bag and transported distally by a roller pump. No major complications were seen. The general outcome was excellent in all cases, and reanastomosis under optimal bowel conditions was achieved in all patients without further problems.
    Type of Medium: Electronic Resource
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