Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Electronic Resource
    Electronic Resource
    Renal prostaglandins: Relationship to the development of blood pressure and concentrating capacity in pre-term and full term healthy infants (1979)
    Springer
    European journal of pediatrics 132 (1979), S. 253-259 
    Details
    ISSN: 1432-1076
    Keywords: Renal prostaglandins ; cAMP ; Blood pressure ; Concentrating capacity ; Neonatal period
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationships between urinary prostaglandins (PGs)E2 and F2α and the postnatal development of blood pressure and renal concentrating capacity were investigated in 14 pre-term and 32 full term healthy infants. Mean PGE2 and PGF2α excretion was 18.9 and 10.1 ng/h/1.73 m2, respectively, in pre-term infants. In full term infants mean urinary PGE2 was signifincantly lower (13.4 ng/h/1.73 m2) and PGF2α significantly higher (22.2 ng/h/1.73 m2). The decrease of the PGE2/PGF2α ratio (P〈0.001) was accompanied by an increase in blood pressure. High PGE2 levels in pre-term infants were inversely correlated with urinary cAMP excretion. A decreasing PGE2/PGF2α ratio in full term infants was associated with increasing urinary osmolality. After intranasal administration of antidiuretic hormone (DDAVP) in 8 full term infants the increase in urinary osmolality and cAMP excretion was accompanied by a drop in PGE2 excretion to less than half the basal values. These findings suggests that the postnatal changes in urinary PG excretion are associated with a concomittant increase in blood pressure and in the concentrating capacity of the neonatal kidney.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00496848
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Effects of ADH on the activity and function of the renin-angiotensin-aldosterone system in infants and in children (1976)
    Springer
    European journal of pediatrics 122 (1976), S. 303-308 
    Details
    ISSN: 1432-1076
    Keywords: Renin-angiotensin-aldosterone system ; Antidiuretic hormone ; Urinary sodium excretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei Säuglingen zwischen der 1. und 25. Lebenswoche und bei Kindern zwischen dem 1. und 14. Lebensjahr wurden Renin im Plasma und Aldosteron im Urin in Abhängigkeit von der Natriumausscheidung des Endharns gemessen. Es fand sich eine reziproke Beziehung, die zeigt, daß die hohen Renin- und Aldosteronwerte der Säuglingszeit durch die niedrige Natriumaufnahme mit der Nahrung bedingt sind. Ein zusätzlicher Stimulus ist das Hypothalamus-Hypophysenhinterlappen-System, da durch antidiuretisches Hormon (ADH) Renin und Aldosteron gesenkt werden, was zu einer vermehrten Natriumausscheidung im Harn führt. Die Untersuchungen lassen eine Rückkoppelung zwischen dem Renin-Angiotensin-Aldosteron-System und der ADH-Sekretion erkennen, und diese Rückkoppelung scheint für den Wasser- und Elektrolythaushalt während der Säuglingszeit von Bedeutung zu sein.
    Notes: Abstract In babies ranging in age from 1 to 25 weeks and in children between 1 and 14 years, plasma renin activity and urinary aldosterone activity were determined in relation to urinary sodium excretion. A reciprocal correlation was found demonstrating that the hyperactivity of the renin-angiotensin-aldosterone system is stimulated in infants by a low sodium intake. A second stimulus was observed in the influence of the hypothalamo-neurohypophyseal system, when the plasma renin activity was suppressed by administration of antidiuretic hormone and sodium excretion increased due to a decreased aldosterone activity. Our study suggests that there exists a feedback between the renin-angiotensin-aldosterone system and ADH release and that this feedback plays an important role in the regulation of water and electrolyte balance in the young infant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00481512
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    Urinary cyclic AMP and renal concentrating capacity in infants (1977)
    Springer
    European journal of pediatrics 124 (1977), S. 113-119 
    Details
    ISSN: 1432-1076
    Keywords: Antidiuretic hormone ; Cyclic AMP ; Concentrating capacity ; Infant kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 15 infants between 1 and 31 weeks the effect of antidiuretic hormone (ADH) on the renal concentrating capacity and urinary cyclic AMP (cAMP) was tested. A significant decrease of urine flow and a significant increase of osmolality, urea and cAMP was observed indicating that the distal nephron of the infant kidney is responsive to exogenous ADH and that its effect is mediated by cAMP. The results of a second series with 52 normally hydrated infants demonstrate that the nonlinear age-related increase of osmolality and urea in urine is accompanied by a similar pattern of cAMP excretion, pointing out that the maturation of the concentrating capacity seems to be related to an increasing responsiveness of the cAMP system to ADH. Furthermore the results raise the possibility that increasing concentrations of urea and solutes in the medulla and papilla of the infant kidney may have—in the presence of very low ADH secretion—an additional stimulating effect on cAMP formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00477546
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    Dimorphie des Kupfer(I)-butyrats (1978)
    Springer
    Naturwissenschaften 65 (1978), S. 594-595 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00364915
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    Computer-assisted assignment of peptides with non-standard amino acids (1995)
    Springer
    Journal of biomolecular NMR 5 (1995), S. 183-192 
    Details
    ISSN: 1573-5001
    Keywords: 2D NMR ; Proteins ; Automated assignment ; Graph theory ; Fuzzy mathematics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary A comprehensive peptide assignment program and its application to a cyclic peptide, cyclosporin A, are presented in this paper. A group of graph theoretical algorithms using fuzzy logic are discussed with the aid of examples from cyclosporin A. The algorithms deal with heavily overlapped peaks, recover disjointed and distorted spin coupling networks, and include strategies for sequence-specific assignment. A procedure to extend the Protein Knowledge Base for automatically assigning non-standard amino acid residues is also presented. The program is capable of completely automated assignment for small peptides (∼20 residues). For such molecules, it is insensitive to whether the peptide chain is cyclic or acyclic, and to whether amide protons are present or absent. For larger peptides/proteins, more user interaction is required and the sequence-specific assignment step usually must proceed through fragments smaller than the full length to avoid problems due to occurrence of a combinatorial explosion. The program can be applied as a rigorous tool to check manual assignments. The fuzzy graph theoretical concepts built in the program are illustrated with 2D proton spectra of a peptide, but may be extended to higher-dimensional spectra, other biopolymers, natural products and other organic structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00208809
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    A histochemical study of glycosidases in benign prostatic hyperplasia and in prostatic carcinoma in the human (1978)
    Springer
    Urological research 6 (1978), S. 103-107 
    Details
    ISSN: 1434-0879
    Keywords: Prostatic adenoma ; Prostatic carcinoma ; Glycosidases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In benign hyperplasia marked β-glucuronidase and N-acetyl-β-glucosaminidase activity was seen in the prostatic epithelium whereas the reactions for 5 other glycosidases were only slight or negative. The intensity of the reaction for the glycosidases in prostatic carcinoma was dependent upon the degree of the differentiation. The possible importance of glycosidases for the invasiveness of prostatic carcinoma is briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255581
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    Alternation of interleukin-1α production and interleukin-1α binding sites in mouse brain during rabies infection (1996)
    Springer
    Archives of virology 141 (1996), S. 573-585 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have evaluated the effect of rabies virus infection on interleukin-1α(IL-1α) production and its receptors in mouse brain. Study of virus dissemination in the central nervous system (CNS) showed a massive infection of main brain structures from day 4 post infection (p.i.) up to the agony stage on day 6 p.i. At the same time, IL-1α concentrations increased in cortical and hippocampal homogenates, whereas no change was detected in serum. In non-infected mice, IL-1α binding sites were observed in the dentate gyrus, the cortex, the choroid plexus, the meninges and the anterior pituitary. During rabies virus infection, a striking decrease in IL-1α binding sites was observed on day 4 p.i. with a complete disappearance on day 6 p.i., except in the pituitary gland where they remained at control level. In conclusion, concomitantly with the early rabid pathological signs, brain IL-1α production and IL-1α binding sites are specifically and significantly altered by brain viral proliferation. These results indicate that IL-1α could be involved in the brain response to viral infection as a mediator and could participate in the genesis of the rabies pathogeny.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01718318
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Experimentelle Rekonstruktion der Orbita beim Schaf mit biodegradablen Implantaten (1998)
    Springer
    Mund-, Kiefer- und Gesichtschirurgie 2 (1998), S. S117 
    Details
    ISSN: 1434-3940
    Keywords: Schlüsselwörter Orbitarekonstruktion ; Resorbierbare Implantate ; Polylaktat ; Key words Orbital reconstruction ; Biodegradable implants ; Polylactide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In a complex animal model in sheep, polydioxanone (PDS®) and polylactic membranes were used for the reconstruction of large orbital-wall defects. In a long-term experiment over 1 year, polylactic implants alone showed the best performance as compared with combinations involving autogenous bone grafts and titanium miniplate fixation. As soon as these polylactic implants are approved for human surgery, they will be used to solve the still challenging problem of anatomical reconstruction of large comminuted fractures of more than one orbital wall.
    Notes: Zusammenfassung In einem experimentellen Modell wurden biodegradierbare Membranen aus Polydioxanon (PDS ® ) resp. Polylaktat zur Rekonstruktion großer Orbitawanddefekte bei Schafen verwendet. Im Langzeitversuch über ein Jahr zeigten diejenigen Rekonstruktionen die besten Resultate, bei welchen ausschließlich biodegradierbare Implantate aus Polylaktat zur Anwendung kamen. Bei gleichzeitiger Verwendung von autologen Knochentransplantaten und Titan-Miniplatten-Osteosynthesen war die anatomische Form der rekonstruierten Orbita weniger zuverlässig gewährleistet. Es darf erwartet werden, dass die klinische Zulassung der Polylaktat-Implantate die chirurgische Wiederherstellung ausgedehnter Trümmerfrakturen mehrerer Orbitawände wesentlich erleichtern wird und zu vorhersehbaren, anatomischen Rekonstruktionen führt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00014455
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    Darstellung und Fluoreszenzeigenschaften von Kupfer(I)-Carboxylaten (1978)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 442 (1978), S. 225-229 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Preparation and Fluorescence Properties of Copper (I) CarboxylatesBy reduction of copper(II) carboxylates with ascorbic acid in aqueous solutions some aromatic copper(I) compounds can easily be obtained by precipitation. Powder x-ray photographs of copper(I) propionate and copper(I) monochloroacetate have similar characteristic interferences as copper(I) acetate, from which a layer structure is known. All the here described copper(I) carboxylates are fluorescent, indicating that oxygen atoms behave as sufficently strong donors, but most of them and especially those with tetragonal structure, do not change their fluorescence colour by cooling in liquid nitrogen like many copper(I) complexes with nitrogen bases do (fluorescence thermochromism). Fluorescence thermochromism occurs however at copper(I) 3-hydroxybenzoate. This presumably results from a lower symmetry.
    Notes: Einige aromatische Kupfer(I)-Verbindungen lassen sich auf einfache Weise in wäßriger Lösung durch Reduktion mit Ascorbinsäure darstellen. Die Debyeogramme von Kupfer(I)-Propionat und Kupfer(I)-monchloracetat haben die ähnlichen charakteristischen Interferenzringe wie Kupfer(I)-acetat, welches Schichtenstruktur besitzt. Da alle hier beschriebenen Kupfer(I)-carboxylate fluoreszieren, zeigt es sich, daß die Sauerstoffatome ausreichend starke Donoreigenschaften haben. Die meisten und speziell die, welche tetragonale Struktur besitzen, ändern ihre Fluoreszenzfarbe nicht im Gegensatz zu vielen Kupfer(I)-Amin-Komplexen (Fluoreszenzthermochromie). Kupfer(I)-3-hydroxybenzoat zeigt jedoch Fluoreszenzthermochromie, was wahrscheinlich auf eine geringere Symmetrie Zurückzuführen ist.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19784420130
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    Lovastatin induces differentiation of Mono Mac 6 cells (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 13 (1995), S. 273-277 
    Details
    ISSN: 0263-6484
    Keywords: adhesion ; HMG-CoA reductase ; HUVEC ; mevalonate ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The proliferation of human monocytic Mono Mac 6 cells was significantly retarded by treatment with lovastatin (LOV, 10 μM) for 72 h. Treatment of Mono Mac 6 cells with LOV increased surface protein expression of monocyte-associated CD14 and the integrin-chain CD11b towards levels found in isolated human blood monocytes. These effects were dose-dependent and completely reversed by the isoprenoid precursor mevalonate (MVA). LOV failed to induce growth retardation and upregulation of CD11b or CD14 in the less mature premonocytic U937 cell line. While CD11b expression was comparable in Mono Mac 6 cells treated with LOV (10 μM), TNF (100 U ml-1) or LPS (10 ng ml-1), upregulation of CD14 by LOV was less pronounced. Basal CD23 expression was unaffected by LOV but markedly reduced by treatment with TNF or LPS. Moreover, LOV enhanced Mono Mac 6 adhesiveness to human umbilical vein endothelial cells to levels found in isolated human blood monocytes, probably due to the increased CD11b and CD14 expression. In conclusion, LOV can induce differentiation of monocytic cells which is reflected by the retardation of growth, expression of CD14 and CD11b, and enhanced adhesiveness.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290130408
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...