Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    The mechanism of insulin secretion after oral glucose administration (1977)
    Springer
    Diabetologia 13 (1977), S. 269-272 
    Details
    ISSN: 1432-0428
    Keywords: Insulin secretion ; oral glucose ; reflex insulin secretion ; portal vein ; dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Concentrations of immunoreactive insulin activity and of blood glucose were measured in portal and peripheral venous blood in six conscious dogs after oral administration of 1.0 g/kg glucose. Portal venous samples were obtained either by chronic catheterization or by direct puncture of the portal vein through a London-cannula. Portal venous IRI was already significantly increased 5 min after the onset of the stimulus. Peripheral venous IRI pattern reflected this early increase, but the peripheral venous blood glucose level was unchanged. The results indicate that the early peripheral venous IRI increase reflects a pancreatic insulin secretory reflex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01219711
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Estimation of pancreatic IRI output rate and its relation to glucose tolerance in normal anaesthetized dogs (1975)
    Springer
    Diabetologia 11 (1975), S. 291-299 
    Details
    ISSN: 1432-0428
    Keywords: Insulin secretion rate ; pancreatic blood flow ; mathematic model ; IRI concentration ; blood glucose ; glucose assimilation ; dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pancreaticoduodenal and portal venous blood flows were recorded electromagnetically in anaesthetized dogs. Blood glucose and IRI were measured in the arterial, portal, and peripheral venous as well as in the intestinal venous blood. By a mathematical model the actual net IRI output of the whole pancreas was estimated. Under basal conditions it is 10.2±2.4 mU/min (n = 30; 26 kg mean body wt). After i.v. glucose injection, IRI output is rapidly enhanced. The biphasic nature of this reaction was unequivocally demonstrated by consideration of the ratio IRI output: blood glucose. Pancreaticoduodenal blood flow increases transiently in relation to the increased blood glucose concentration. The IRI secretion rate is well correlated with the blood glucose concentration and to the amounts of glucose or of blood reaching the whole pancreas. It is also correlated with the portal IRI concentration. The overall peripheral venous or arterial IRI concentrations are correlated with the IRI secretion rate, but not in all individual experiments. The different phases of IRI output (basal rate, stimulated output 1–10 min and 10–60 min) show no influence on each other, nor are they correlated with the peripheral IRI concentration area. Basal IRI output is negatively correlated with the glucose assimilation constants. These constants or the peripheral B G areas, however, are independent of the stimulated IRI output rate. However, both the assimilation constants and the peripheral BG areas are related to the peripheral IRI concentration areas. Hepatic uptake of insulin and dynamics of pancreatic blood flow seem to contribute considerably to the estimated correlation pattern.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422394
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Pancreatic blood flow in conscious dogs after oral administration of glucose (1976)
    Springer
    Diabetologia 12 (1976), S. 133-136 
    Details
    ISSN: 1432-0428
    Keywords: Pancreatic blood flow ; oral glucose test ; insulin secretion ; reflex
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Dogs with an electromagnetic flowprobe implanted around the superior pancreaticoduodenal artery and with an hydraulic occluder implanted upstream from the flowprobe were examined between the 3rd and the 8th postoperative day. During an oral glucose load, blood flow increased from the beginning of administration to about 25 minutes, but not when blood glucose and plasma IRI exhibit their maxima. The rise of pancreatic blood flow is assumed to be produced by reflexes similar to those stimulating insulin secretion and exocrine pancreatic function during the early phase of an oral glucose load.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00428978
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Unwinding of poly(ethylene oxide) chains grafted on silica under a shear flow of cyclohexane, observed by spin-labelling (1999)
    Springer
    Colloid & polymer science 277 (1999), S. 965-971 
    Details
    ISSN: 1435-1536
    Keywords: Key words Solid/fluid interface processes ; Amorphous and polymeric materials ; Magnetic resonance and relaxation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Poly(ethylene oxide) chains of molecular weight 2000 have been grafted on pyrogenic silica, spin-labelled at their free end and put into contact with cyclohexane. The electron paramagnetic resonance of the nitroxide free radical gives evidence of two specific environments: namely, trains adsorbed on the solid with a restricted motion and loops and tails protruding into solution with a high mobility. The dynamic parameters such as the rotational correlation time and the static ones such as the fraction of each population have been evaluated. Under a flow of solvent the unwinding of the chains has been observed with increasing flow rate in our experimental range. Some mechanisms are proposed to explain this behaviour.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050476
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Thickness of a silica-tethered poly(ethylene oxide) layer measured by spin labeling (1995)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 33 (1995), S. 2189-2198 
    Details
    ISSN: 0887-6266
    Keywords: poly(ethylene oxide) ; EPR spectroscopy ; spin labeling ; silica grafting ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: EPR spectroscopy of labeled poly(ethylene oxide) (PEO) grafted on silica has been used to characterize the conformation and local dynamics of the chains. Grafted molecules of MW 2000 with grafting ratios of 0.045, 0.057, 0.126, and 0.42 molecules/nm2 were in contact with benzene. The mobility of the label was compared with that observed for solution of PEO from very diluted to highly concentrated and even bulk PEO. Thus, the concentration inside the grafted layer could be evaluated and also the thickness, which evolves rather linearly with the grafting ratio. © 1995 John Wiley & Sons, Inc.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/polb.1995.090331602
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...