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  • 1990-1994  (7)
  • pharmacokinetics  (4)
  • Biochemistry and Biotechnology  (2)
  • Combined exposure  (1)
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Material
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Clinical studies in workers engaged in maintenance of watermark moulds in a paper mill (1992)
    Springer
    International archives of occupational and environmental health 64 (1992), S. 141-145 
    Details
    ISSN: 1432-1246
    Keywords: Watermark ; Mould ; Combined exposure ; Metals ; Xylene ; Health effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thirty subjects engaged in maintenance and repair of moulds used for producing watermarks on paper were studied, along with 27 control subjects from the same paper mill. The workers were simultaneously exposed to copper, chromium, zinc, xylol, and fumes of sulphuric acid in the course of their work. The study subjects were investigated for clinical, occupational, radiological haematological and psychological details. The aforementioned combined exposure was found to be responsible for a high prevalence of symptoms pertaining to the respiratory system and higher nervous functions. Breathlessness (26.7%), expectoration (10.0%) and emphysema (10.0%) were significantly higher among the exposed subjects. The exposed subjects also showed lowered visuomotor coordination and delayed reaction to light and sound stimuli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00381482
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pharmacokinetics and dosage regimen of cephalexin in buffalo calves (Bubalus bubalis) following single intravenous and intramuscular administration (1990)
    Springer
    Veterinary research communications 14 (1990), S. 59-62 
    Details
    ISSN: 1573-7446
    Keywords: buffalo ; cephalexin ; pharmacokinetics ; treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00346385
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Measurement and regulation of the culture reduction state in Clostridium acetobutylicum (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 38 (1991), S. 181-190 
    Details
    ISSN: 0006-3592
    Keywords: solventogenic metabolism ; NADH content ; NADH fluorescence ; continuous fermentation ; butanol biosynthesis ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: With a constant glucose feed concentration, the change in the continuous culture dillution rate resulted in an altered fermentation profile and the cellular NADH content. The cultures growing at high dillution rates demonstrated an oxidative metabolism low NADH and butanol concentrations. The low specific NADH flourescence (F/X) at high butanol production rates suggested that a rapid regeneration of NADH to NAD is essential for a high solventogenic culture activity. The culture florescence and butanol concentration remained constant in the solventogenic dilution rate range of D = 0.05-0.2 h-1 with an inverse relationship between the specific flourescence (F/X) and the specific butanol production rate, qB. Flourometric NADH observations were confirmed by enzymatic NADH determination. The stiochiometric “Fermentation Equation” was used to check the experimental data consistency and to investigate the role of the available biosynthetic and reduction energy on the culture metabolic activities under different growth conditions. The butanol concentration in the broth was stabilized in a fed-batch process when the culture NADH fluorescence was being controlled through the addition of fresh medium.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260380210
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    NADH fluorscence in a carbon-limited fermentation (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 38 (1991), S. 191-195 
    Details
    ISSN: 0006-3592
    Keywords: continuous flow acetone-butanol fermentations ; reduction energy ; solvent production activity ; inlet sugar concentrations ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The continuous flow acetone-butanol fermentation conducted at lowered inlet feed sugar concentrations and at a constant dilution rate D =0.075 h-1 demonstrated a significant decreases in the availability of the cell population “reduction energy” (F/X), resulting in an exclusive accumulation of intermediate acids under those conditions. The cultures resumed its solvent production activity when the inlet sugar concentration in the feed stream was increased from 20 to 40 g/L at the same low growth/dilution rates. A linear correlation between the culture reduction content (F/X) and the specific butanol rate (qB) was observed under the present conditions, indicating the necessity of the NADH availability for the increased solvent production.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260380211
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Disposition kinetics, urinary excretion and dosage regimen of kanamycin in buffalo calves following single intravenous administration (1993)
    Springer
    Veterinary research communications 17 (1993), S. 219-225 
    Details
    ISSN: 1573-7446
    Keywords: buffalo ; disposition ; dose ; kanamycin ; pharmacokinetics ; serum ; urine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The disposition kinetics and appropriate dosage regimen for kanamycin were investigated in buffalo calves following a single intravenous dose of 10 mg/kg body weight. The distribution and elimination half-lives were 0.12±0.01 h and 1.94±0.11 h, respectively. The apparent volume of distribution and total body clearance were 0.2±0.01 L/kg and 92.9±3.69 ml/kg/h, respectively. About 74% of the administered dose was excreted in urine in 24 h. A suitable dosage regimen for the intravenous administration of kanamycin was also calculated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01839170
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Pharmacokinetics and dosage regimen of cefotaxime in cross-bred calves following single intramuscular administration (1994)
    Springer
    Veterinary research communications 18 (1994), S. 313-318 
    Details
    ISSN: 1573-7446
    Keywords: calves ; cefotaxime ; cephalosporin ; dose ; intramuscular ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The pharmacokinetics, penetration into erythrocytes and plasma protein binding of cefotaxime were investigated in cross-bred calves. Following a single intramuscular dose of cefotaxime (10 mg/kg), the absorption half-life and elimination half-life were 0.13±0.03 h and 2.97±0.72 h, respectively. The apparent volume of distribution and total body clearance were 3.28±0.72 L/kg and 0.78±0.08 L/kg per h, respectively. The extent of penetration into erythrocytes was 24–40% of the total blood concentration. Cefotaxime was bound to plasma proteins of calves to the extent of 25.5–33.6%. A satisfactory intramuscular dosage regimen for cefotaxime in calves would be 11 mg/kg followed by 10 mg/kg at 7 h intervals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01839199
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Pharmacokinetics following a single intravenous administration and a dosage regimen for sulfadoxine in buffalo calves (Bubalus bubalis) (1992)
    Springer
    Veterinary research communications 16 (1992), S. 215-219 
    Details
    ISSN: 1573-7446
    Keywords: pharmacokinetics ; dosage regimen ; sulfadoxine ; Bubalus bubalis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01839158
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    Paper (German National Licenses)
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