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  • 1
    Electronic Resource
    Electronic Resource
    Complementation of a DNA repair deficiency in six human tumor cell lines by chromosome 11 (1992)
    Springer
    Human genetics 〈Berlin〉 88 (1992), S. 524-528 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Human tumor cells, after x-irradiation during the G2 phase of the cell cycle, show an abnormally high frequency of persistent chromatid breaks and gaps resulting from deficient DNA repair. Addition of a single human chromosome 11 from normal fibroblasts by micro-cell fusion to cell lines from six different tumors resulted in efficient repair of the radiation-induced damage to the level in normal cells. For one of the cell lines, addition of the long arm of chromosome 11 was sufficient to restore repair efficiency. In four of the six tumor lines, restoration of efficient DNA repair by chromosome 11 was associated with tumor suppression in nude mice. These results suggest that chromosome 11 carries a DNA repair gene or genes that complement the repair deficiency of tumor cells and that this gene for at least one tumor is localized to the long arm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219338
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  • 2
    Electronic Resource
    Electronic Resource
    Displacement of the normal pituitary gland by sellar and juxtasellar tumours: surgical-MRI correlation and use in differential diagnosis (1994)
    Springer
    Neuroradiology 36 (1994), S. 372-375 
    Details
    ISSN: 1432-1920
    Keywords: Pituitary adenoma ; Craniopharyngioma ; Rathke cleft cyst ; Magnetic resonance imaging ; Gadolinium DTPA ; Normal pituitary gland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the position of the normal pituitary gland as estimated by gadolinium (Gd)-DTPA-enhanced MRI, with its position at surgery in 40 patients with intra- and juxtasellar tumours: 22 pituitary adenomas, 4 craniopharyngiomas, 7 meningiomas, 2 germinomas, and 5 Rathke cleft cysts. In 37 of these, the normal gland showed more intense contrast enhancement than the adjacent tumour, from which it could be differentiated by Gd-DTPA-enhanced MRI, especially in the sagittal plane. The direction of displacement of the normal pituitary gland correlated well with tumour type, so that its position proved helpful in the differential diagnosis. The normal gland was typically displaced superiorly by pituitary adenomas, inferiorly by craniopharyngiomas, and anteriorly by germinomas. It showed variable displacement by Rathke cleft cysts, and was not usually displaced by meningiomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00612121
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  • 3
    Electronic Resource
    Electronic Resource
    MRI of pituitary adenomas: the position of the normal pituitary gland (1994)
    Springer
    Neuroradiology 36 (1994), S. 295-297 
    Details
    ISSN: 1432-1920
    Keywords: Pituitary adenoma ; Magnetic resonance imaging ; Gadolinium ; DTPA ; Normal pituitary gland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The position of the normal pituitary gland, assessed using gadolinium-enhanced MRI was compared with the position found at surgery for pituitary adenoma in 25 patients. The tumours were five microadenomas and 20 macroadenomas. Using T1-weighted imaging, the anterior lobe could be differentiated on the sagittal image in five patients (20%) and on the coronal image in four (16%). The high intensity of the posterior lobe could be differentiated using T1-weighted sagittal imaging in 13 patients (52%). The normal pituitary gland, which enhanced more strongly than tumour, could be differentiated using Gd-DTPA-enhanced MRI on the sagittal images in 22 cases (88%) and on the coronal image in 17 (68%). In seven patients, the normal pituitary gland surrounded the tumour; it was displaced superiorly in 14 cases and superioposterorly in two but in no case was it displaced anteriorly or downwards.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593264
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  • 4
    Electronic Resource
    Electronic Resource
    Observation and statistical analysis of ZZ Piscium (1993)
    Springer
    Astrophysics and space science 210 (1993), S. 205-206 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract To examine the non-linear oscillation and period change of white dwarf variables, ZZ Psc is discussed observationally. As a result of data reduction we found two major periods, 680 seconds and 860 seconds, but could not find chaotic behavior of ZZ Psc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00657900
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  • 5
    Electronic Resource
    Electronic Resource
    Chaotic behavior and statistical analysis of some Mira and Sr stars (1993)
    Springer
    Astrophysics and space science 210 (1993), S. 149-151 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Visual light curves of some Mira and semiregular variable stars are analyzed to search for their chaotic and statistical behaviour. Discussion are also given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00657886
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  • 6
    Electronic Resource
    Electronic Resource
    Pseudarthrosis and delayed union after anterior cervical fusion (1993)
    Springer
    International orthopaedics 17 (1993), S. 286-289 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Cette étude analyse les causes possibles de pseudarthrose et de retard de consolidation après tentative d'arthrodèse antérieure du rachis cervical et précise les mesures préventives. Les symptômes créés par ces problèmes sont également évalués. Parmi les 443 cas d'arthrodèse antérieure du rachis cervical faits dans notre Institution entre 1965 et 1988, on note 15 pseudarthroses ou fusions retardées. Les causes de ces troubles de consolidation peuvent être divisées en deux catégories principales: défaut d'alignement des corps vertébraux et contention post-opératoire inappropriée. Certains de ces cas étaient symptomatiques, probablement à cause d'une mobilité anormale, d'une compression médullaire secondaire à un glissement postérieur ou une rotation du corps vertébral supérieur, d'une déformation en cyphose, ou d'une anomalie au niveau vertébral adjacent. Les 15 cas ont été traités par une reprise de l'arthrodèse qui a conduit à une fusion osseuse complète. Quatre des cinq cas symptomatiques ont eu une récupération complète après la chirurgie secondaire.
    Notes: Summary Anterior cervical spine fusion was carried out on 443 cases between 1965 and 1988 with pseudarthrosis or delayed union in 15 (3.4%). The causes of these complications were malalignment and faulty postoperative care. Symptoms resulted from abnormal mobility, cord compression due to posterior slip or rotation of the upper vertebral body, kyphotic deformity or a problem at the adjacent level. Four out 5 cases with symptoms recovered successfully after a second operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00181700
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  • 7
    Electronic Resource
    Electronic Resource
    Antibodies to 65Kd heat-shock protein were elevated in rheumatoid arthritis (1994)
    Springer
    Clinical rheumatology 13 (1994), S. 261-264 
    Details
    ISSN: 1434-9949
    Keywords: Rheumatoid Arthritis ; Heat-Shock Protein ; Mycobacterium Leprae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Antibodies to 65Kd heat-shock protein (hsp) of mycobacterium leprae were measured by enzyme-linked immunosorbent assay (ELISA) in the three immunoglobulin classes in paired sera and synovial fluids of patients with rheumatoid arthritis (RA). Titers of anti-hsp antibody were expressed by optical density (OD) values for sera or indexes (OD values divided by amounts of immunoglobulin in each class) for synovial fluids and for their paired sera. Indexes of anti-hsp antibody were higher in synovial fluids than those in sera at 15/18 for IgG, 17/18 for IgA and 16/18 for IgM class. These results suggest the participation of anti-hsp antibodies to synovitis in RA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02249023
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