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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 45 (1979), S. 247-251 
    ISSN: 1432-0533
    Keywords: Infantile neuro-axonal dystrophy ; Skin ; Conjunctiva ; Spheroids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The diagnosis of infantile neuro-axonal dystrophy (INAD) in a 5-year-old patient was confirmed by the ultrastructural study of neuromuscular, skin and conjunctival biopsy specimens. Abnormal networks of smooth membranous, lamellar and tubular profiles were found in presynaptic terminals and in conjunctival and dermal axons. INAD is the first neurological disease outside the group of storage disorders in which skin and conjunctival biopsies contribute significantly to the diagnosis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 38 (1977), S. 247-250 
    ISSN: 1432-0533
    Keywords: Conjunctival biopsy ; Skin biopsy ; Adrenoleukodystrophy ; Nerve bundles ; Vacuolated eccrine glands
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Conjunctival and skin biopsies were performed in an 111/2 year-old caucasian male affected by adrenoleukodystrophy (ALD). In Schwann cells surrounding myelinated axons in conjunctival and dermal nerve bundles, empty clefts and a few arrays of lamellae were discovered. The vacuolization in the eccrine glands of the skin, another striking feature, has not been reported previously in ALD. The obtained results suggest that ALD can be diagnosed in skin specimens precluding major surgery for biopsy. They provide support to the hypothesis of Schaumburg et al. (1975) that ALD is a generalized metabolic disorder.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-9071
    Keywords: Sleep ; brown adipose tissue ; rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In young rabbits the slope of the temperature in the deep cervical region close to brown adipose tissue increased during desynchronized sleep at low ambient temperature. No increase occurred at neutral ambient temperature. In control rabbits (after disappearance of brown adipose tissue), the slope of deep cervical temperature did not increase during desynchronized sleep at low or neutral ambient temperatures.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2072
    Keywords: Benzodiazepine ; Triazolam ; Human ; Heart rate ; Respiratory rate ; Sleep ; Noise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The influence of triazolam on cardiac and respiratory activity of healthy male subjects was examined during nights disturbed by airplane noises and during undisturbed nights. Twenty-four subjects, divided into three groups of eight, slept in the laboratory for 7 nights (N0–N6). Following a double blind design, group A (control group) received a placebo every night. Group B received 0.25 mg triazolam and group C received 0.5 mg on nights N3, N4 and N5. On the other nights, they received a placebo. For all three groups, the nights N0, N3 and N5 were disturbed by 32 semi-randomly distributed airplane noises. Air and wall temperatures (20° C) and air humidity (10° C, 52%) were kept constant. Sleep measures, heart rate and respiratory rate were continuously recorded. Results showed that the largest dose of hypnotic drug produced an increase in tonic heart rate in the first part of each night throughout the treatment period (N3, N4, N5). When compared to baseline disturbed night N0, the phasic cardiac response to the noises was significantly attenuated on only the 1st treatment night (N3). Triazolam had no significant effect on nocturnal respiratory rate. No after-effects of the drug were observed for cardiac and respiratory activity on the withdrawal night (N6). The results suggest that, with regard to the drug action, there was either an increase in arousal threshold or a dissociation between long-lasting and short-lasting modifications of heart rate. Contrary to the single night attenuation of phasic cardiac responses, there was no drug tolerance for the hypnotic-related increase in tonic heart rate.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 34 (1975), S. 97-108 
    ISSN: 1439-6327
    Keywords: Coefficient of Evaporative Heat Loss ; Convective Coefficient ; Mixed Convection ; Dripping Sweat Loss ; Coefficient d'évaporation ; Coefficient de convection ; Convection mixte ; Sueur non évaporée
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs ont déterminé expérimentalement chez l'homme, le coefficient d'échange de chaleur par évaporation (h e), lors d'aplications d'échelons d'humidité en air calme (V a〈-0,2 m/s). Une telle détermination exige une mouillure intégrale de la peau qui implique dès lors une perte de sueur par ruissellement. La récupération de la sueur de ruissellement permet l'évaluation de l'évaporation totale: celle-ci se faisant sur la peau et au niveau des gouttes de sueur durant leur trajet de la surface cutanée jusqu'au bac dans lequel la sueur de ruissellement est récupérée. Une évaluation de l'évaporation parasite se faisant sur la sueur de ruissellement permet d'estimer l'évaporation cutanée et par conséquent le coefficienth e. Dans nos conditions expérimentales: $$E = S - SNE - 0,005{\text{ }}SNE{\text{ }}(P_{S_{H_2 O} } - P_{a_{H_2 O} } )$$ oùE = débit évaporatoire cutané (g/h);S = débit sudoral total (g/h);SNE = débit de sueur non évaporée (g/h); $$P_{S_{H_2 O} } $$ = pression saturante de vapeur d'eau à la température cutanée (en mb) et $$P_{a_{H_2 O} } $$ = pression partielle de vapeur d'eau ambiante (mb). Le coefficient d'évaporation en air calme ainsi déterminé est de 5,18±0,22 W/m2 · mb.
    Notes: Abstract The authors have determined the coefficient of evaporative heat loss of the human body (h e) by means of humidity steps in low air movement (V a≤0,2 m/s). Such a determination requires a fully wetted skin and this implies therefore some loss of dripping sweat. The collection of this dripping sweat allows the determination of the total evaporation: this evaporation exists on the skin surface and around the drops during their fall from the skin to the oil pan where dripping sweat is collected. An estimation of this dripping sweat evaporation allows to assess the skin evaporation and, consequently, the evaporative coefficienth e. In these experimental conditions: ( $$E = S - SNE - 0,005{\text{ }}SNE{\text{ }}(P_{S_{H_2 O} } - P_{a_{H_2 O} } )$$ ) whereE is the skin evaporative rate (g/h);S = total sweat rate (g/h);SNE = the nonevaporative sweat rate (g/h); $$P_{S_{H_2 O} } $$ = the partial pressure of satured water (at $$\bar T_S $$ ) on skin (mb) and $$P_{a_{H_2 O} } $$ the partial pressure of water vapor in ambient air (mb). The coefficient of evaporative heat loss in low air movement thus found, is 5,18±0,22 W/m2 · mb.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 57 (1988), S. 499-506 
    ISSN: 1439-6327
    Keywords: Heat acclimation ; Sweating rate ; Exercise ; Body temperatures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Body temperature regulation was studied in 6 male subjects during an acclimation procedure involving uninterrupted heat exposure for 5 successive days and nights in a hot dry environment (ambient temperature =35° C, dew-point temperature =7° C; air velocity = 0.2 m·s−1). Data were obtained at rest and during exercise (relative mechanical workload =35% $$\dot V_{{\text{O}}_{{\text{2 max}}} } $$ ). At rest, hourly measurements were made of oesophageal and 4 local skin temperatures, to allow the calculation of mean skin temperature, and of body motility and heart rate. During the working periods these measurements were made at 5 min intervals. Hourly whole-body weight loss was measured at rest on a sensitive platform scale while in the working condition just before starting and immediately after completing the bicycle exercise. The results show that, in both exercise and at rest, the successive heat exposures increased the sweat gland output during the first 3 days. Afterwards, sweat rate decreased without any corresponding change, in body temperature. For the fixed workload, the sweat rate decline was associated with a decrease in circulatory strain. Adjustments in both sweating and circulatory mechanisms occur in the first 3 days of continuous heat exposure. The overall sweat rate decline could involve a redistribution of the regional sweating rates which enhances the sweat gland activities of skin areas with maximal evaporative efficiencies.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 55 (1986), S. 113-122 
    ISSN: 1439-6327
    Keywords: Fluid intake ; Heart rate ; Plasma volume ; Plasma osmolarity ; Gastric emptying
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Five young unacclimatised subjects were exposed for 4 h at 34
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 55 (1986), S. 123-129 
    ISSN: 1439-6327
    Keywords: Plasma volume ; Aldosterone ; Renin activity ; Arginine vasopressin ; Cortisol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study examines the relationships between vascular changes and endocrine responses to prolonged exercise in the heat, associated with dehydration and rehydration by fluids of different osmolarity. Five subjects were exposed, in a 34
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1439-6327
    Keywords: Recovery ; Rectal temperature ; Adaptation to work in heat ; Local skin temperature ; Récupération ; Température rectale ; Adaptation au travail à la chaleur ; Température cutanée locale
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Nous avons suivi l'évolution de la température rectale (T re ) au cours de la récupération consécutive à diverses charges thermiques (exogène, endogène ou mixte) avant et après une adaptation aux conditions expérimentales (10 jours consécutifs d'exposition à la condition C 1). Trois sujets ont subi après un repos de 30 min (T a = 28
    Notes: Summary Evolution of rectal temperature (T re ) during recovery in different air temperatures was studied following different patterns of heat load before and after adaptation to work in heat (10 consecutive days). Three subjects have been exposed, after a 30 min rest period (T a = 28
    Type of Medium: Electronic Resource
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