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  • 1985-1989  (3)
  • Notfallendoskopie  (2)
  • Arterial Occlusive Diseases  (1)
  • 32.30.Rj
  • 1
    ISSN: 1432-1440
    Keywords: Hemorheology ; Acute Phase Proteins ; Vascular Surgery ; Carotid Arteries ; Arterial Occlusive Diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 39 patients with hemodynamically significant stenoses of the internal carotid artery thrombendarterectomy was performed. Hemorheological properties and plasma protein levels were studied pre- and postoperatively over a period of 14 days. In comparison to age-matched healthy controls preoperative plasma viscosity, red cell aggregation, fibrinogen, haptoglobin and alpha-1-antitrypsin were significantly elevated. After surgical trauma there was an increase in fibrinogen, alpha-1-antitrypsin, haptoglobin and ceruloplasmin, whereas alpha-2-macroglobulin, immunglobulin A and immunglobulin G decreased significantly. Plasma viscosity, red cell aggregation, red cell filterability, fibronectin and immunglobulin M remained unchanged. We conclude that our patients showed a non specific chronic “hematological stress syndrome” with raised acute phase reactants and corresponding hemorheological changes preoperatively; despite postoperative acute phase reaction no further deterioration of the rheological parameters could be observed; this might be caused by a decrease of plasma proteins with high frictional ratios compensating the increase of acute phase proteins. Besides, tissue damage and consecutive acute phase reaction in carotid arterial surgery seem to be of relatively minor degree.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 943-944 
    ISSN: 1435-2451
    Keywords: Bleeding peptic ulcer ; Recurrent hemorrhage ; Emergency endoscopy ; Ulcusblutung ; Rezidivblutung ; Notfallendoskopie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Durch ein aggressiveres endoskopisch-chirurgisches Therapieschema (endoskopische Blutstillung unabhängig vom Forrest-Stadium, F Ia: Auch nach erfolgreicher Unterspritzung OP innerhalb 6 h, F Ib, II: Kontroll-Endoskopie und evtl. nochmalige Unterspritzung) konnten die Ergebnisse -signifikant verbessert werden: Senkung der Re-Blutungsrate von 35% auf 16% (P〈0,05), der Notfall-OP-Rate wegen Re-Blutung von 66% auf 28% (P 〈 0,05), Senkung der Letalität von 14,3% auf 6,3%.
    Notes: Summary Using a new therapeutic regimen for bleeding peptic ulcers, the results improved significantly: endoscopic hemostasis regardless of the Forrest stage, F I a: early operation within 6 h, even if the primary endoscopic hemostasis was successful; F I b, 11: second endoscopy within 24 h and repeat hemostasis, if necessary. The rate of rebleeding was reduced from 35% to 16% (sP〈 0.05), the rate of emergency operations due to rebleeding from 66% to 28% (P〈0.05), and mortality decreased from 14.3% to 6.3%.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 369 (1986), S. 869-870 
    ISSN: 1435-2451
    Keywords: Medical decision making ; Bleeding peptic ulcer ; Recurrent haemorrhage ; Emergency endoscopy ; Entscheidungsfindung ; Ulcusblutung ; Rezidivblutung ; Notfallendoskopie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das Hauptproblem in der Therapie des blutenden Ulcus ist die Rezidiv-Blutung nach konservativer oder endoskopischer Blutstillung. Die dann erforderliche Not-OP hat eine hohe Letalität (16%) gegenüber der elektiven OP (7%). Neue Therapie-Richtlinien: Endoskopische Blutstillung in jedem Blutungsstadium. Forrest la: Frühoperation. Forrest I b, II: Kontrollendoskopie nach 24 h. Die wiederholte endoskopische Kontrolle und Blutstillung führt vermehrt zu einer elektiven und selektiven Chirurgie mit einer Abnahme der postoperativen Komplikationen.
    Notes: Summary The main problem in therapy of bleeding peptic ulcer is recurrent haemorrhage after conservative or endoscopic haemostasis. Mortality of emergency operations due to rebleeding was more than twice as high (16%) as mortality of elective operations (7%). New regimen: Endoscopic haemostasis regardless of Forrest stage. Forrest I a: Early operation. Forrest I b, 11: Second endoscopy after 24 h. Repeated endoscopic treatment leads to more elective and selective surgery with decrease of postoperative complications.
    Type of Medium: Electronic Resource
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