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  • 1
    Electronic Resource
    Electronic Resource
    The dispersed pancreas: Transplantation without islet purification in totally pancreatectomized dogs (1977)
    Springer
    Diabetologia 13 (1977), S. 495-502 
    Details
    ISSN: 1432-0428
    Keywords: Pancreatectomy ; experimental diabetes in dogs ; collagenase digestion ; transplantation ; spleen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty-eight mongrel dogs were made diabetic by total pancreatectomy. Fifteen untreated pancreatectomized animals survived for a mean of 7±1 (SEM) days. Thirty-three dogs were divided into five groups and received autotransplants to the spleen of pancreatic fragments dispersed by collagenase digestion for 0, 10, 15, 20 or 25 minutes. Animals transplanted with tissue digested for 0 minutes or for 10 minutes remained hyperglycaemic (mean survival 22±12 days and 28±9 days). Normoglycaemia occurred in all but one of 21 dogs transplanted with tissue digested for 15–25 minutes. Two weeks after transplantation tolbutamide and glucose tolerance curves in the group receiving tissue digested for 20 minutes most closely resembled those of normal animals. Glucose tolerance test K values in dogs receiving tissue digested for 15, 20 and 25 minutes were 1.20±0.19 percent, 1.60±0.25 percent and 0.78±0.08 percent, respectively. The K values of the transplanted animals were significantly different from the K value of 0.35±0.05 percent in the apancreatic control dogs (p 〈 0.001). The mean K value of the dogs transplanted with tissue digested for 20 minutes was significantly better than the value in the dogs transplanted with tissue digested for 25 minutes (p 〈 0.02), but was significantly less than the K value (3.30±0.27 percent) obtained in 22 normal control dogs (p 〈 0.005). Hyperglycaemia recurred immediately following splenectomy in 12 normoglycaemic dogs 10 weeks after transplantation and all animals died. The remaining normoglycaemic transplanted dogs survived for at least six months. Histological examination of spleens from the transplanted animals showed the presence of islet and exocrine tissue within the splenic pulp with no apparent destructive effect on surrounding splenic parenchyma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01234503
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  • 2
    Electronic Resource
    Electronic Resource
    Neutron polarization from the reaction ^1^4C(d,n)^1^5N
    Amsterdam : Elsevier
    Nuclear Instruments and Methods 120 (1974), S. 469-476 
    Details
    ISSN: 0029-554X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0029-554X(74)90011-1
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  • 3
    Electronic Resource
    Electronic Resource
    Neutron polarization from the reaction ^9Be(α, n)^1^2C
    Amsterdam : Elsevier
    Nuclear Instruments and Methods 120 (1974), S. 477-482 
    Details
    ISSN: 0029-554X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0029-554X(74)90012-3
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  • 4
    Electronic Resource
    Electronic Resource
    A photochemical route to the unsaturated β-lactam, N-methyl-azetinone: A thermally labile ring-system
    Amsterdam : Elsevier
    Tetrahedron Letters 16 (1975), S. 1335-1338 
    Details
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0040-4039(00)72135-6
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  • 5
    Electronic Resource
    Electronic Resource
    Cyclobutyl edge participation in the thermal elimination of carbon monoxide from polyalicyclic ketones
    Amsterdam : Elsevier
    Tetrahedron Letters 16 (1975), S. 1339-1342 
    Details
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0040-4039(00)72136-8
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  • 6
    Electronic Resource
    Electronic Resource
    The structure of tris(tetraphenyl imidodiphosphato)ytterbium(III) (1982)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 38 (1982), S. 2813-2817 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567740882010024
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  • 7
    Electronic Resource
    Electronic Resource
    Genauigkeit und Korrekturparameter beim Kristalljustiergerät (1970)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 26 (1970), S. 583-589 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567740870002820
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  • 8
    Electronic Resource
    Electronic Resource
    Experimentelle Untersuchungen über die pathophysiologischen Folgen der Mesentericastenose auf den Magen (1973)
    Springer
    Langenbeck's archives of surgery 333 (1973), S. 29-38 
    Details
    ISSN: 1435-2451
    Keywords: Intestinal Ischemia ; Mesenteric Blood Flow ; Acute Gastric Ulceration ; Gastric Blood Flow ; Mesenteric Artery Stenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Untersucht wurde an 11 Hunden die pathophysiologischen Folgen einer verringerten Mesentericadurchblutung auf die Coeliacastrombahn und ihre Auswirkungen auf Säuresekretion und Magendurchblutung 1. Die Stenose der Arteria mesenterica superior hat einen Anstieg der Säuresekretion des Magens, eine signifikante Zunahme der Coeliacadurchblutung sowie eine Zunahme der direkten Magendurchblutung zur Folge. 2. Die Klemmung der Verbindungsarkade zwischen Coeliaca- und Mesentericastrombahn (Arteria gastroduodenalis) läßt sowohl die Magendurchblutung als auch den Säureausstoß wieder absinken. 3. Nach Stenose oder Verschluß der Arteria mesenterica superior sind bei 8 von 11 Tieren hämorrhagische Erosionen oder einzelne bzw. multiple oberflächliche Magenulcera nachweisbar. 4. Diese Befunde machen die Bedeutung der Minderdurchblutung der Àrteria mesenterica superior bei der Uleusgenese im Experiment wahrscheinlich und haben wichtige Wechselwirkungen zwischen Coeliaca-und Mesentericastrombahn nachgewiesen.
    Notes: Summary The gastric response to acute reduction of intestinal blood flow has been evaluated in 11 dogs under general anesthesia: 1. The reduction of mesenteric blood flow to 53 % causes an increase in celiac blood flow from 380 ml/min to 440 ml/min (p 〈 0,05) an increase in direct gastric blood flow taken at the gastric artery and an almost 4 fold increase in total acid output to 75 mval/l. 2. After temporary occlusion of the gastroduodenal artery — the main collateral vessel between celiac and mesenteric artery — the mean values of both the gastric blood flow and total acid output decrease close to the preoperative level. 3. Stenosis of the mesenteric artery with at least 50 % reduction in intestinal blood flow for a period of 4 h or its occlusion is followed by acute gastric ulceration (single or multiple) or extensive hemorrhagic gastritis in 8 out of 11 dogs. 4. In agreement with Boley et al. it is concluded, that acute intestinal ischemia in the dog is a possible major pathological stimulus to increased gastric blood flow, to hyperacidity and acute gastric ulceration with or without ulcerbleeding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01261197
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  • 9
    Electronic Resource
    Electronic Resource
    Zur Wertigkeit der intraoperativen Kontrollangiographie im femoro-popliteo-cruralen Bereich (1981)
    Springer
    Langenbeck's archives of surgery 354 (1981), S. 89-100 
    Details
    ISSN: 1435-2451
    Keywords: Peripheral vascular surgery ; Intraoperative arteriography ; Detecting complications ; Immediate occlusion ; Avoiding technical errors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die intraoperative Angiographie wurde bei 307 Operationen (Thrombendarteriektomie (TEA)n =107 = 34,8 %; Venenbypass (VBP)n = 145 = 47,2 %; Kunststoffbypass (KBP)n = 44 = 14,4 %, zusammengesetzte Rekonstruktionenn = 11 = 3,6 %) wegen chronisch obliterierender Arteriopathie im femoro-poplitealen und cruralen Bereich angewendet. Die kumulative Korrekturrate betrug 11, 7% (TEA: 18, 6%, VBP: 8,2%, KBP:6,8%); Fehler waren am häufigsten nach TEA gefolgt von VBP und KBP. Revisionen nach Sofortverschluß (SFV) verliefen in 7,4 % erfolgreich (TEA: 8,4 %; VBP: 5,5 %, KBP: 6,8 %). Bei technisch einwandfreiem Angiogramm gelangen Korrekturen in 13,1 % nicht (TEA: 11,2 %; VBP: 13,8 %; KBP: 13,6 %). Röntgenbefunde fraglicher Wertigkeit wurden in 6,8 % akzeptiert, 4 Sofortverschlüsse wurden gezählt (1,7%). In 3,6% der Fälle war das Arteriogramm technisch nicht einwandfrei. Die intraoperative Kontrollangiographie wird auf Grund der vorliegenden Erfahrung als wertvolles Hilfsmittel zur Qualitätskontrolle gefäßrekonstruktiver Eingriffe empfohlen. Technische Fehler können entdeckt und sofort behoben werden.
    Notes: Summary The intraoperative angiography was employed in 307 vascular reconstructive procedures (thrombendarterectomies (TEA)n = 107 = 34.8 %; Veinbypass (VBP)n = 145 = 47.2 %; fabric grafts (KBP)n = 44 = 14.4 %) within the femoro-popliteal and crural region. 11.7% unsuspected technical errors were detected (TEA 18.6 %; VBP 8.2 %; KBP: 6.8 %) by angiography and sucessfully revised prior to wound closure. Errors were most common after thrombendarterectomies followed by VBP and KBP. Revisions after immediate failures were performed successfully in 7.4 % (TEA: 8.4 %, VBP : 5.5 %, KBP: 6.8 %). Lesions on X-ray of questionable significance were accepted in 6.8%, and followed by 4 immediate occlusions (1.7%). In 3.6% of the angiogramms the film was not satisfactorily exposed from the technical point of view. We think intraoperative angiography is a valuable adjunct in peripheral vascular surgery helping to detect and correct technical errors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271156
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  • 10
    Electronic Resource
    Electronic Resource
    Hämorheologie und Akute Phase Reaktion nach Thrombendarteriektomie der extracraniellen Arteria carotis (1988)
    Springer
    Journal of molecular medicine 66 (1988), S. 379-384 
    Details
    ISSN: 1432-1440
    Keywords: Hemorheology ; Acute Phase Proteins ; Vascular Surgery ; Carotid Arteries ; Arterial Occlusive Diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 39 patients with hemodynamically significant stenoses of the internal carotid artery thrombendarterectomy was performed. Hemorheological properties and plasma protein levels were studied pre- and postoperatively over a period of 14 days. In comparison to age-matched healthy controls preoperative plasma viscosity, red cell aggregation, fibrinogen, haptoglobin and alpha-1-antitrypsin were significantly elevated. After surgical trauma there was an increase in fibrinogen, alpha-1-antitrypsin, haptoglobin and ceruloplasmin, whereas alpha-2-macroglobulin, immunglobulin A and immunglobulin G decreased significantly. Plasma viscosity, red cell aggregation, red cell filterability, fibronectin and immunglobulin M remained unchanged. We conclude that our patients showed a non specific chronic “hematological stress syndrome” with raised acute phase reactants and corresponding hemorheological changes preoperatively; despite postoperative acute phase reaction no further deterioration of the rheological parameters could be observed; this might be caused by a decrease of plasma proteins with high frictional ratios compensating the increase of acute phase proteins. Besides, tissue damage and consecutive acute phase reaction in carotid arterial surgery seem to be of relatively minor degree.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01737940
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