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  • 1985-1989  (5)
  • Complement components  (1)
  • Excision  (1)
  • Inorganic Chemistry  (1)
  • Lymphadenopathy  (1)
  • MAT 13762 cells  (1)
Datenquelle
Materialart
Erscheinungszeitraum
Jahr
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Malignant sacrococcygeal teratoma: improved survival with chemotherapy (1989)
    Springer
    Pediatric surgery international 4 (1989), S. 202-204 
    Details
    ISSN: 1437-9813
    Schlagwort(e): Malignant sacrococcygeal teratoma ; Excision ; Chemotherapy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Between 1954 and 1985, 15 cases of malignant sacrococcygeal teratoma were treated in our institution. Median age at presentation was 20 months (range 9–46 months); there were 14 females and 1 male. Six cases presenting prior to 1970 were treated without chemotherapy with a median survival of 2 months (range 1–7 months). Five patients treated from 1971 to 1979 had tumour excision plus vincristine, actinomycin D, and cyclophosphamide (VAC). Three received radiotherapy in addition and median survival was 11 months (range 0–31 months). Four patients presenting since 1980 had chemotherapy alone after tumour excision. 1 receiving VAC and adriamycin and the remaining patients cisplatinum, bleomycin, and VP16. All these are alive and disease free (median follow-up 27 months; range 15–96 months). It is concluded that initial surgery aimed at complete excision followed by aggressive chemotherapy gives good results.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00181986
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  • 2
    Digitale Medien
    Digitale Medien
    A simple method for elution of IgA deposits from the skin of patients with dermatitis herpetiformis (1989)
    Springer
    Archives of dermatological research 281 (1989), S. 406-410 
    Details
    ISSN: 1432-069X
    Schlagwort(e): Dermatitis herpetiformis ; Immunoglobulins ; Complement components ; Elution
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary To better understand the role of autoimmunity in the pathogenesis of dermatitis herpetiformis, linear IgA bullous dermatosis or other skin disorders, the antigenic specificity of the immune reactants bound in vivo in the skin must be identified. In order to do so, one must first be able to elute these immune reactants from the skin. We describe here a simple method of eluting not only specifically bound IgG, but also IgA and other immunoglobulins and complement components from skin biopsy material. The method involves cutaneous washing of the entrapped serum proteins in PBS pH 7 and pH 5 buffers followed by specific immunoglobulin elutions at pH 3 and 2. The IgA deposits which could not be removed by this treatment were eluted by a combination of low pH (0.5 M citrate pH 2) and a chaotropic agent (2 M NaCl). The relative concentration of IgA in eluates when quantitated by fluoroimmunoassay were three-to five-fold higher in dermatitis herpetiformis skin biopsy specimens, than in eluates of bullous pemphigoid or normal skin biopsy specimens.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00455326
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  • 3
    Digitale Medien
    Digitale Medien
    Cellular and secreted tumor plasminogen activator: The effects of NaCl (1986)
    Springer
    Cellular and molecular life sciences 42 (1986), S. 433-435 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Plasminogen activator ; NaCl ; metastasis ; MAT 13762 cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Plasminogen activator, secreted by metastatic tumor cells, was strongly inhibited in buffer or tissue culture medium containing physiological concentrations of NaCl. Intact cells, however, expressed strong activity under similar conditions. Thus, if plasminogen activator is involved in invasion and metastasis, the cellular activity, acting as an ectoenzyme, may be more important than secreted enzyme under physiological conditions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02118645
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  • 4
    Digitale Medien
    Digitale Medien
    Non-tuberculous mycobacterial lymphadenitis in children (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 751-754 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Lymphadenopathy ; Atypical mycobacteria ; Non-tuberculous mycobacterial lymphadenitis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Eighty-six children (44 males, 42 females) were identified as having non-tuberculous mycobacterial lymphadenitis. The diagnostic criteria were either culture of the organism from the affected lymph node (n=68), or, when culture was negative, a positive skin test with non-tuberculous mycobacterial antigens and negative skin test responses to tuberculin purified protein derivative (PPD) in association with typical histological features (n=18). All children had histopathological findings of granulomatous inflammation with caseation and/or acid-fast bacilli. Eighty-two percent of the children were under 5 years of age at presentation and 30% were less than 2 years old. Most (79%) were city dwellers. Lymph node enlargement had been present for less than 6 months in almost all children (97.5%) and was almost exclusively in the face and neck region (97%). Disease was confined to the involved lymph nodes in 56% but had extended beyond the confines of the infected node to form a collar stud abscess in 38% and 6% presented with a skin sinus. Extranodal extension did not show any statistically significant association with the duration of lymphadenopathy. The duration of lymphadenopathy had been greater in those children in whom an organism was not isolated on culture resected tissue χ2, P〈0.01). All children were treated surgically, and recurrence occurred in five patients. This study describes the clinical and demographic characteristics of non-tuberculous mycobacterial lymphadenopathy in children in a population in which tuberculous adenitis is rare. Recognition of these features may allow earlier diagnosis and appropriate surgical therapy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00443102
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  • 5
    Digitale Medien
    Digitale Medien
    Reaktionen von (η2-Ethen)bis(triphenylphosphan)-platin(0) mit dimerem Hexafluorthioaceton Darstellung und Struktur von Platinacyclopentan- und -cyclopropanderivaten (1986)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 542 (1986), S. 46-52 
    Details
    ISSN: 0044-2313
    Schlagwort(e): Chemistry ; Inorganic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Beschreibung / Inhaltsverzeichnis: Reactions of (η2-Ethene)bis(triphenylphosphane)platinum(0) with Dimeric Hexafluorothioacetone. Preparation and Structure of Platina Cyclopentane and Cyclopropane DerivativesThe five-membered (CS)2Pt ring 1 was obtained by the reaction of 2, 2, 4, 4-tetrakis(trifluoromethyl)-1,3-dithietane and (η2-ethene)bis(triphenylphosphane)platinum(0) at low temperatures. 1 is converted at its melting point to the three-membered CSPt ring derivative 2, with elimination of one molecule of hexafluorothioacetone. 2 is also formed directly when the reaction is conducted at temperatures above +30°C. 2 was characterized by an X-ray Structural analysis.
    Notizen: Der fünfgliedrige (CS)2Pt-Cyclus 1 kann aus 2, 2, 4, 4-Tetrakis(trifluormethyl)-1,3-dithietan und (η2-Ethen)bis(triphenylphosphan)-platin(0) bei tiefer Temperatur erhalten werden. 1 wandelt sich an seinem Schmelzpunkt unter Abspaltung eines Moleküls Hexafluorthioaceton in den um zwei Ringglieder reduzierten CSPt-Ring 2 um, der auch auf direktem Wege durch Umsetzen des Dithietans bei Temperaturen oberhalb von +30° zugänglich ist. 2 konnte erstmals durch eine Kristallstrukturbestimmung charakterisiert werden.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/zaac.19865421108
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