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  • 11
    Electronic Resource
    Electronic Resource
    Central sites and mechanisms of the hypotensive and bradycardic effects of the narcotic analgesic agent fentanyl (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 296 (1977), S. 255-261 
    Details
    ISSN: 1432-1912
    Keywords: Baroreceptor reflex arc ; Carotid sinus nerve ; Centrally mediated vagal bradycardia ; Fentanyl ; Nucleus of the solitary tract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In dogs, anaesthetized with chloralose, fentanyl (5 μg/kg i.v.) augmented the bradycardia produced by electrical stimulation of the carotid sinus nerves. In contrast, the same dose of the drug did not change the bradycardic response to stimulation of the nucleus of the solitary tract (NTS) indicating that a central facilitation of baroreceptor impulses occurs within the NTS, probably at the first synapse of baroreceptor reflex fibres. Bilateral destruction of the NTS caused a ful-minating hypertension and tachycardia similar to that after cutting the baroreceptor afferent fibres. After both procedures, fentanyl (20 μg/kg i.v.) produced marked hypotension and bradycardia. The bradycardic effect was abolished by cutting both vagal nerves when the dogs were pretreated with a β-adrenoceptor blocking agent (S 2395, 50 μg/kg i.v.). The results provide evidence that the NTS is not the main site of action either for the hypotensive effect or for the vagally mediated bradycardia of fentanyl. Since the dorsal nucleus of the vagal nerve was destroyed together with the NTS, this nucleus does also not appear to be a major site of the action of fentanyl. Blockade of dopamine receptors by haloperidol or pimozide or of serotonin receptors by methysergide did not change the hypotensive, bradycardic and sympathoinhibitory effects of fentanyl.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00498691
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  • 12
    Electronic Resource
    Electronic Resource
    Quantitative analysis of the size distribution of target-and targetoid fibres employing the method of daeves and beckel for mixed distributions (1979)
    Springer
    Acta neuropathologica 45 (1979), S. 215-220 
    Details
    ISSN: 1432-0533
    Keywords: Skeletal muscle ; Denervation atrophy ; Target fibres ; Analysis of size distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An analysis of frequency distribution is performed in 250 target and targetoid fibres each from the anterior tibial muscle of a case with rapidly proceeding denervation atrophy. Following plane measurements on cross sections the size data were analysed according to the method of Daeves and Beckel [1] for mixed distributions. Three homogeneous normally distributed populations could thus be extracted from the mixed distributed sample. The largest population represents target fibres with a normal size range, while the second one encloses hypertrophic fibres, and the third and smallest one consists of fibres ranging within atrophic size limits. These findings support the previous presumption that targets predominantly occur in fibres of normal size and can therefore be regarded as manifestations of an early stage of denervation atrophy. The targetoid fibres, on the contrary, are of an atrophic size by 84%, while only a small population of about 15% contains targetoid fibres of a normal size on cross section.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00702673
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  • 13
    Electronic Resource
    Electronic Resource
    Partial transtentorial displacement of the cerebellum and the brain stem in hydrocephalus — A primary condition or a result of treatment? (1976)
    Springer
    Acta neurochirurgica 33 (1976), S. 151-165 
    Details
    ISSN: 0942-0940
    Keywords: brain stem, cerebellum ; transtentorial displacement ; hydro-cephalus communicans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two oases of upward displacement of parts of the brain stem and the cerebellum are discussed. In both cases shunts for a hydrocephalus had been operating for a long time (three and a half years in one and seven months in the other). One infant had a meningomyelocele but no complete Arnold-Chiari malformation. The cause of the hydrocephalus in the other case was doubtful, but was thought to be transtentorial displacement of the brain stem and the cerebellum causing traction on the pons and consequent meningeal fibrosis with obstruction of the cisterna pontis. In this case osseous hypoplasia of the posterior fossa was excluded by craniometry, so the upward displacement must have been due to hypoplasia of the tentorium cerebelli and its low attachment to the occiput, bringing about a narrowing of the infratentorial space. The authors believe the condition to be a primary malformation, and reject the hypothesis of secondary herniation following long standing supratentorial decompression. The concept of a primary malformation is supported by previous descriptions of the condition in cases with spina bifida, Arnold-Chiari malformation, and hydrocephalus without shunting, as well as by other features in the cases which have been recorded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01886666
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  • 14
    Electronic Resource
    Electronic Resource
    The influence of chronic deep brain stimulation on excitability and morphology of the stimulated tissue (1979)
    Springer
    Acta neurochirurgica 47 (1979), S. 123-129 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Bipolar electrical stimulations of the rostral hippocampus and of the amygdala were performed at irregular intervals in wakeful unrestrained cats via chronically implanted glass-insulated stainless steel electrodes. The excitability of the stimulated tissue remained unchanged during the whole investigation period of six months up to one and a half years, as was revealed by regularly performed comparisons of shape, latency, and amplitude of evoked potentials elicited by electrical stimulation of the rostral hippocampus and recorded within the ipsilateral mammillary body. The histological examination of the stimulated tissue revealed a fibrillary gliosis due to the trauma caused by the insertion of the electrodes, but no signs of additional tissue damage due to electrical stimulation or chronic mechanical irritation. The results indicate that it is possible to perform therapeutic stimulations of deep brain structures for long periods without inducing relevant changes in morphology or electrical responsiveness of the stimulated tissue. No kindling phenomena are to be expected, if the stimulations are performed at irregular intervals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01404668
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  • 15
    Electronic Resource
    Electronic Resource
    Umlenkung eines ebenen Freistrahles durch eine Querströmung aufgrund von turbulenter Vermischung und Druckwirkung (1981)
    Springer
    Archive of applied mechanics 51 (1981), S. 9-16 
    Details
    ISSN: 1432-0681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Summary The deflection of a plane turbulent jet in a crossflow is described by a model which takes the effects of entrainment as well as those of crossflow pressure into account. Using this model the centerline and the spread of the jet and the mean velocity averaged over its cross-section can be calculated. Asymptotic analytic solutions are given for the case where the velocity of the unperturbed crossflow is much smaller than that of the unperturbed jet. A comparison of the present calculations with experimental results of other authors shows good agreement.
    Notes: Übersicht Zur Beschreibung der Umlenkung eines ebenen turbulenten Freistrahles durch eine Querströmuug wird ein Modell entwickelt, bei dem sowohl die Einsaugwirkung des Strahles als auch die Druckwirkung der Querströmung auf den Strahl berücksichtigt werden. Hiermit können die Strahlmittellinie, die Strahlbreite und die über einen Strahlquerschnitt gemittelte Geschwindigkeit berechnet werden. Es werden analytische Näherungslösungen für die Fälle angegeben, in denen die Geschwindigkeit der ungestörten Querströmung wesentlich kleiner als diejenige des ungestörten Strahles ist. Ein Vergleich der berechneten Größen mit experimentellen Ergebnissen anderer Autoren zeigt gute Übereinstimmung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00535951
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  • 16
    Electronic Resource
    Electronic Resource
    Druckverteilung an einem schräg angeströmten Rotationsellipsoid (1983)
    Springer
    Archive of applied mechanics 53 (1983), S. 337-344 
    Details
    ISSN: 1432-0681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Summary The threedimensional steady flow of an incompressible inviscid fluid around a prolate spheroid at incidence is studied. The displacement effect of the body on the uniform onset flow is represented by means of a source distribution on its surface. The modification of the flow by the lift acting on the spheroid is represented by means of a source doublet sheet on the wake surface. The comparison of the calculated pressure distribution on the surface of the spheroid with a pressure distribution measured by other authors shows that the agreement is substantially better when the lift effect is taken into account.
    Notes: Übersicht Es wird die dreidimensionale stationäre Strömung eines inkompressiblen reibungsfreien Fluids um ein schräg angeströmtes Rotationsellipsoid untersucht. Die Verdrängungswirkung des Körpers auf die ungestörte Parallelströmung wird durch eine Quellverteilung auf seiner Oberfläche beschrieben. Die Änderung der Strömung durch den Auftrieb, den er erfährt, wird durch eine Dipolschicht auf der Nachlauffläche simuliert. Der Vergleich der berechneten Druckverteilung an der Oberfläche des Ellipsoids mit einer von anderen Autoren gemessenen Druckverteilung zeigt, daß die Berücksichtigung des Auftriebseffektes zu einer wesentlich besseren Übereinstimmung führt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00532522
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  • 17
    Electronic Resource
    Electronic Resource
    Mixed chemodectoma-ganglioneuroma of the conus medullaris region (1982)
    Springer
    Acta neuropathologica 57 (1982), S. 275-281 
    Details
    ISSN: 1432-0533
    Keywords: Spinal cord ; Conus medullaris ; Mixed chemodectoma and ganglioneuroma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Report of a 33-year-old man with a yearlong historory of low-back pain radiating into the left leg. Neurologic examination upon admission tto the hospital revealed a spinal compression syndrome at the lovel L5. Laminectomy at L4/5 revealed an encapsulated intradural tumor measuring 4×2.5×2.5 cm. The tumor was attached to the dorsal root L4 and extended downward to the conus region. Light and electron microscopy revealed features mostly consistent with a mixed chemodectoma and ganglioneuroma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00692183
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  • 18
    Electronic Resource
    Electronic Resource
    Dielectric properties of thin sections of barium titanate ceramics (1981)
    Springer
    Applied physics 25 (1981), S. 195-200 
    Details
    ISSN: 1432-0630
    Keywords: 77
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Thin sections in the thickness range down to 3–5 μm were produced from bariumtitanate ferroelectric ceramics. The small signal dielectric constant, as well as hysteresis loops were measured. Significant deviations from the bulk properties were observed, when the thickness of the sample was decreased to the average diameter of the grains. The measured results are discussed proposing a model with internal stresses and a distorted surface layer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00902972
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  • 19
    Electronic Resource
    Electronic Resource
    UNESCO (1975)
    [s.l.] : Nature Publishing Group
    Nature 253 (1975), S. 85-85 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR,-As visiting scientists at the Weiz-mann Institute, we find the recent UNESCO anti-Israel resolution doubly abhorrent. First, as scientists and educators, we are appalled at the biased, politicised and cowardly vote, which has made a travesty of an organisation established to help wipe out ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/253085a0
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  • 20
    Electronic Resource
    Electronic Resource
    Chronic electrical stimulation of the thalamic unspecific activating system in a patient with coma due to midbrain and upper brain stem infarction (1979)
    Springer
    Acta neurochirurgica 47 (1979), S. 235-244 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Chronic intermittent bipolar electrical stimulation of the left nucleus reticulatus polaris thalami was performed in a patient in a state of subcoma due to ischaemic infarction of wide medial parts of the midbrain, mainly the tegmentum, and the right-sided mediobasal parts of the forebrain. Stimulation immediately resulted in autonomic reactions and behavioural arousal reactions during the periods of stimulation. Longterm effect consisted of a rise in the level of clinical responsiveness for a period of seven weeks. A preexistent severe pneumonia disappeared completely after one week of stimulation and returned after seven weeks. The results are discussed on the basis of the pathoanatomical findings and of the physiological functions of the damaged as well as of the stimulated areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01406406
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