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  • 1
    Electronic Resource
    Electronic Resource
    Immunological studies on the acidic chromogranins and on dopamine β hydroxylase (EC 1.14.2.1) of bovine chromaffin granules (1974)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 22 (1974), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1974.tb12201.x
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  • 2
    Electronic Resource
    Electronic Resource
    IMMUNOLOGICAL STUDIES ON A MEMBRANE PROTEIN (CHROMOMEMBRIN B) OF CATECHOLAMINE-STORING VESICLES (1973)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 20 (1973), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Rabbits were immunized with chromomembrin B, i.e. a membrane protein isolated from chromaffin granules of bovine adrenal medulla. When the rabbit sera were tested by immunodiffusion in the presence of various detergents, only negative results were obtained, whereas with complement fixation antibodies could be demonstrated. With this method the subcellular distribution of chromomembrin B in bovine adrenal medulla was determined. The results demonstrate that this protein is specifically localized in the membranes of chromaffin granules. In the mitochondrial and microsomal fractions it is present only in small amounts which are attributable to a contamination of these fractions with chromaffin granules. The subcellular distribution of chromomembrin R in bovine splenic nerves indicates that this antigen is also found in the membranes of noradrenalinestoring vesicles of sympathetic nerve. Chromomembrin B or a related antigen was detected in chromaffin grades isolated from pig and rat adrenal and in those isolated from a human phaeochromocytoma. It is also present in total membranes obtained from posterior and anterior hypophysis, but it is absent from membranes isolated from parotid gland, liver and adrenal cortex. This paper illustrates how a membrane protein which requires detergents for its solubilization can be characterized and measured by immunological methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1973.tb00068.x
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  • 3
    Electronic Resource
    Electronic Resource
    Kinetic study of the hydration mechanism of vitamin B6 and related compounds (1970)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 92 (1970), S. 6134-6139 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00724a006
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  • 4
    Electronic Resource
    Electronic Resource
    Theg-factor of the 181 keV level of99Tc and hyperfine fields of Tc in Fe, Co, Ni (1971)
    Springer
    The European physical journal 243 (1971), S. 166-170 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Theg-factor of the 181 keV-level of99Tc has been redetermined by the spin rotation method. Measurements with polycrystalline sources of Tc in Fe, Co, and Ni yielded values of the hyperfine fields at the Tc nucleus. $$\begin{gathered} g = + 1.310(25) \hfill \\ H_{hf} (Tc{\mathbf{ }}in{\mathbf{ }}Fe) = ( - )290(15)kOe \hfill \\ H_{hf} (Tc{\mathbf{ }}in{\mathbf{ }}Co) = ( - )170(5)kOe \hfill \\ H_{hf} (Tc{\mathbf{ }}in{\mathbf{ }}Ni) = - 47.8(1.5)kOe. \hfill \\ \end{gathered} $$
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01397861
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  • 5
    Electronic Resource
    Electronic Resource
    Goldanskii-karyagin effect at mössbauerE2-transitions (1974)
    Springer
    The European physical journal 267 (1974), S. 61-70 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Investigations of anisotropic Debye-Waller factors have been carried out mainly using the M1-transitions of57Fe and119Sn. For this case the theory of the Goldanskii Karyagin effect is well established. Mössbauer studies of electric quadrupole interactions in hafnium and tungsten compounds made it necessary to extend the theory to the more complex case of E2-transitions. As the investigated compounds show a strong axial anisotropy of the electric field gradient, a similar behaviour has to be expected in principle for the tensor of the mean-square displacements, which determines the Debye-Waller factor immediately. A fitting procedure taking into account an axial asymmetric Debye Waller factor is worked out and applied to measurements performed with several complex hafnium and tungsten fluorine compounds. With NaWO2F3 the quadrupole interactions of182W,183W, and184W have been measured yieldingQ 5/2+(183W)/Q 2+(182W)=0-86(6) andQ 2+(184W)/Q 2+(182W)=0.955 (3).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01680363
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  • 6
    Electronic Resource
    Electronic Resource
    Determination of hyperfine interactions from partly resolved moessbauer spectra (1972)
    Springer
    The European physical journal 257 (1972), S. 29-42 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Moessbauer spectra with different sets of parameters were calculated. A fit with a superposition of Lorentzians to these theoretical spectra showed, that systematic errors must be expected if the hyperfine structure of the spectrum is only partly resolved. Correction factors for some simple cases are given. Experiments to test the calculations were performed with133Cs (81 keV transition),165Ho (94.7 keV transition) and178Hf (93 keV transition). In all cases fits using the transmission integral and superpositions of Lorentzians showed the expected trends. We get the following results: $$\begin{gathered} ^{133} Cs:\frac{{g_{ex} }}{{g_{gr} }} = 1.90\left( 4 \right) \hfill \\ ^{165} Ho:\tau \left( {94.7keVlevel} \right) = 32\left( 1 \right)ps \hfill \\ \frac{{g_{ex} }}{{g_{gr} }} = 0.77\left( 3 \right) \hfill \\ ^{178} Hf:|H_{eff} \left( {4K,in iron} \right)| = 633\left( {40} \right)KG \hfill \\ |H_{eff} \left( {77K,in iron} \right)| = 630\left( {41} \right)KG. \hfill \\ \end{gathered}$$
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01398195
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  • 7
    Electronic Resource
    Electronic Resource
    Tonsillektomie in Hypotension? (1958)
    Springer
    European archives of oto-rhino-laryngology and head & neck 171 (1958), S. 286-287 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02127283
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  • 8
    Electronic Resource
    Electronic Resource
    Tonsillektomie in Hypotension? (1957)
    Springer
    European archives of oto-rhino-laryngology and head & neck 172 (1957), S. 105-120 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es werden Normtonsillektomien unter Verwendung von Adrenalin mit Mandelausschälungen, die unter Hexamethoniumwirkung durchgeführt wurden, verglichen. Auf die nicht unwesentliche rolle psychischer Faktoren bei der Blutdruckgestaltung intra operationem wird hingewiesen. Eine ausreichende Blutarmut läßt sich bei Verwendung von 2,5 mg Hexamethonium intramuskulär pro kg Körpeergewicht erzielen. Es ist wünschenscwert, den Blutdruck auf Werte, die bei etwa 60–50 mm Hg liegen, zu senken. Vorteile des Verfahrens sind die zumeist geringe Blutung während der Operaation sowie fast trockene Wundverhältnisse nach beendeter Tonsillektomie bei häufig geringer Gewebsreaktion und unter dem Durchschnitt liegenden postoperativen Beschwerden. Nachteilig wirken sich der größere technische Aufwand und ein durch die Hirnanoxie hervorgerufener inkonstanter, aber nicht immer unerheblicher Würg- und Brechreiz aus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02102687
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  • 9
    Electronic Resource
    Electronic Resource
    Reaktoroszillator zur Bestimmung makroskopischer Absorptionsquerschnitte von thermischen Neutronen (1959)
    Springer
    Zeitschrift für angewandte Mathematik und Physik 10 (1959), S. 438-441 
    Details
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01601054
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  • 10
    Electronic Resource
    Electronic Resource
    Bovine adrenal medulla: Synthesis and secretion of radioactively labelled catecholamines and chromogranins (1971)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 271 (1971), S. 193-203 
    Details
    ISSN: 1432-1912
    Keywords: Adrenal Medulla ; Chromogranin ; Catecholamines ; Synthesis ; Secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. 3H-leucine and3H-tyrosine were added to the perfusion medium of isolated bovine adrenal glands in order to study the synthesis and secretion of radioactively labelled catecholamines and proteins. 2. Various times after the injection of the labelled amino acids the soluble proteins of the microsomal fraction were isolated and subjected to polyacrylamide gel electrophoresis in three different buffer systems. The distribution of protein-bound radioactivity within the gels was determined. Most of the label was found to be confined to proteins which behaved like the specific soluble proteins of chromaffin granules, i.e. the chromogranins. 3. Stimulation of the adrenal gland with carbachol induced a release of catechol-amines, protein, and protein-bound radioactivity. In the absence of Ca2+ the secretion of all these components was abolished. The highest specific radioactivity of the proteins secreted upon stimulation was reached 4 h after the injection of the labelled precursors. The labelled proteins, secreted upon stimulation, could be identified as chromogranins. 4. Carbachol induced the release of highly labelled catecholamines after the injection of3H-tyrosine. The highest specific radioactivity of these catecholamines was already observed at the first stimulation with carbachol i.e. 30 min after3H-tyrosine. 5. These results demonstrate that in isolated bovine adrenal glands radioactively labelled chromogranins and catecholamines can be synthesised and can be secreted upon stimulation with carbachol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00998580
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