ZIB

1

Electronic Resource

d-Alanine in germinating Pisum sativum seedlings

Fukuda, M. ; Tokumura, A. ; Ogawa, T. ; [et al.]

Amsterdam : Elsevier

Phytochemistry 12 (1973), S. 2593-2595

add to mindlist on the mindlist

Details

ISSN: 0031-9422

Keywords: Leguminosae ; N-malonyl-d-alanine. ; Pisum sativum ; d-alanine ; pea ; γ-l-glutamyl-d-alanine

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(73)85061-7

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

2

Electronic Resource

Improved isolation method and some properties of soybean gamma-conglycinin

Sato, W. ; Kamata, Y. ; Fukuda, M. ; [et al.]

Amsterdam : Elsevier

Phytochemistry 23 (1984), S. 1523-1526

add to mindlist on the mindlist

Details

ISSN: 0031-9422

Keywords: Glycine max ; Leguminosae ; MW ; electrophoresis ; gamma-conglycinin ; soybean protein

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)83431-7

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

3

Electronic Resource

Increased expression of nucleoside diphosphate kinases/nm23 in human diploid fibroblasts transformed by SV40 large T antigen or ^6^0Co irradiation

Ohneda, K. ; Fukuda, M. ; Shimada, N. ; [et al.]

Amsterdam : Elsevier

FEBS Letters 348 (1994), S. 273-277

add to mindlist on the mindlist

Details

ISSN: 0014-5793

Keywords: Enzyme activity ; Gene expression ; Human diploid cells ; Immortalization ; NDP kinase ; nm23

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology , Physics

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(94)00623-7

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

4

Electronic Resource

The pH-dependent swinging-out of the distal histidine residue in ferric hemoglobin of a midge larva (Tokunagayusurika akamusi)

Akiyama, K. ; Fukuda, M. ; Kobayashi, N. ; [et al.]

Amsterdam : Elsevier

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular 1208 (1994), S. 306-309

add to mindlist on the mindlist

Details

ISSN: 0167-4838

Keywords: (Diptera) ; (T. akamusi) ; CD Soret magnetic ; Distal histidine ; Hemoglobin ; Midge larva ; Pentacoordination

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology , Medicine

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4838(94)90117-1

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

5

Electronic Resource

Examination of previous caesarean section scars by ultrasound (1988)

Fukuda, M. ; Fukuda, Kiyomi ; Mochizuki, M.

Springer

Archives of gynecology and obstetrics 243 (1988), S. 221-224

add to mindlist on the mindlist

Details

ISSN: 1432-0711

Keywords: Vaginal delivery ; Caesarean section ; Previous caesarean section scar ; Ultrasonography ; Lower uterine segment

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary We examined 84 lower segment caesarean section scars by ultrasonography near term. Seventy scars showed good healing with a thickness of the lower uterine segment of more than 3 mm; 14 scars showed poor healing with a thickness of less than 2 mm and loss of continuity. Among 70 patients with good healing, 24 patients delivered vaginally but the remaining 46 patients have had repeat caesarean sections for other obstetric indications. Intraoperative findings in these 46 patients were as follows: Grade I (no thinning of the lower uterine segment), 42; Grade II (thinning and loss of continuity of the lower uterine segment but fetal hair not visible), 4; Grade III (thinning of the lower uterine segment and fetal hair visible), 0. Fourteen patients with poor healing had repeat caesarean sections. Intraoperative findings in these 14 patients were as follows: Grade I, 0; Grade II, 9; Grade III, 5. These results indicate that ultrasound examination detect thinning of the lower uterine segment and may help to determine management.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00932271

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

6

Electronic Resource

Studies on the binding mechanism of fluoroquinolones to melanin (2000)

Fukuda, M. ; Morita, Y. ; Sasaki, K. ; [et al.]

Springer

Journal of infection and chemotherapy 6 (2000), S. 72-76

add to mindlist on the mindlist

Details

ISSN: 1437-7780

Keywords: Key words Ocular melanin ; Melanin affinity ; Fluoroquinolones ; Metal ions ; Binding mechanism

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract In order to elucidate the binding mechanism of melanin and fluoroquinolones (ofloxacin, norfloxacin, ciprofloxacin, lomefloxacin, levofloxacin), we investigated the interaction of fluoroquinolones with compounds such as l-β-(3,4-dihydroxyphenyl) alanine (l-DOPA), l-tyrosine, 5-hydroxy-l-tryptophan, l-tryptophan, and l-phenylalanine, which possess the kind of functional groups that melanin does and are closely related to melanin. The recovery of drugs from the melanin-drug complexes by metal ions of Li, Na, Ka, Mg, Ca, Ba, Cu, Ni, and Fe was demonstrated. Smaller and highly charged cations were found to be more effective for this recovery, and magnesium ions were the most effective of all the ions investigated.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/PL00012154

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

7

Electronic Resource

Increased expression of the ornithine decarboxylase gene in mouse skin by ultraviolet light: detection by in situ hybridization technique (1990)

Fukuda, M. ; Kono, T. ; Ishii, M. ; [et al.]

Springer

Archives of dermatological research 282 (1990), S. 487-489

add to mindlist on the mindlist

Details

ISSN: 1432-069X

Keywords: Ornithine decarboxylase ; Gene expression ; Ultraviolet light ; Tumor promotion ; In situ hybridization

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00402630

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

8

Electronic Resource

Detection of lysyl oxidase gene expression in rat skin during wound healing (1995)

Fushida-Takemura, H. ; Fukuda, M. ; Maekawa, N. ; [et al.]

Springer

Archives of dermatological research 288 (1995), S. 7-10

add to mindlist on the mindlist

Details

ISSN: 1432-069X

Keywords: Key words Lysyl oxidase ; Gene expression ; Wound healing ; Type III collagen

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Lysyl oxidase (LOX) initiates the crosslinking of the lysine-derived aldehyde and plays an essential role in maturation of collagen, for example in wound healing. Although the activity of this enzyme has been examined in various disorders, and a further intriguing aspect of the relationship between LOX and tumorigenesis has recently emerged, its gene expression pattern in tissues is still unknown. We examined LOX gene expression during wound healing in rat skin. In addition, type III collagen gene expression was studied to determine the formation of fibrils. The LOX mRNA level reached a peak by day 3 after injury, which was earlier than that of type III collagen, and continued at a high level until day 22. The type III collagen mRNA level began to rise from day 3 and had increased intensely by day 22. In situ hybridization revealed grains corresponding to LOX mRNA in the fibroblasts of the granulomatous tissue. These results suggest that LOX is produced before collagen synthesis in preparation for crosslinking in the early phase of wound healing.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s004030050014

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

9

Electronic Resource

The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity (1995)

Ueda, H. ; Ikegami, H. ; Yamato, E. ; [et al.]

Springer

Diabetologia 38 (1995), S. 503-508

add to mindlist on the mindlist

Details

ISSN: 1432-0428

Keywords: NSY mouse ; non-insulin-dependent diabetes mellitus ; animal model ; insulin secretion ; isolated islets

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The NSY (Nagoya-Shibata-Yasuda) mouse was established as an inbred strain of mouse with spontaneous development of diabetes mellitus, by selective breeding for glucose intolerance from outbred Jcl∶ICR mice. NSY mice spontaneously develop diabetes mellitus in an age-dependent manner. The cumulative incidence of diabetes is 98% in males and 31% in females at 48 weeks of age. Neither severe obesity nor extreme hyperinsulinaemia is observed at any age in these mice. Glucose-stimulated insulin secretion was markedly impaired in NSY mice after 24 weeks of age. In contrast, fasting plasma insulin level was higher in male NSY mice than that in male C3H/He mice (545±73 vs 350±40 pmol/l, p〈0.05, at 36 weeks of age). Pancreatic insulin content was higher in male NSY mice than that in male C3H/He mice (76±8 vs 52±5 ng/mg wet weight, p〈0.05, at 36 weeks of age). Morphologically, no abnormal findings, such as hypertrophy or inflammatory changes in the pancreatic islets, were observed in NSY mice at any age. These data suggest that functional changes of insulin secretion in response to glucose from pancreatic beta cells may contribute to the development of non-insulin-dependent diabetes mellitus (NIDDM) in the NSY mouse. Although insulin sensitivity was not measured, fasting hyperinsulinaemia in NSY mice suggests that insulin resistance may also contribute to the pathogenesis of NIDDM. Since these findings are similar to the pathophysiologic features of human NIDDM patients, the NSY mouse is considered to be useful for investigating the pathogenesis and genetic predisposition to NIDDM.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00400717

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

10

Electronic Resource

The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity (1995)

Ueda, H. ; Ikegami, H. ; Yamato, E. ; [et al.]

Springer

Diabetologia 38 (1995), S. 503-508

add to mindlist on the mindlist

Details

ISSN: 1432-0428

Keywords: Key words NSY mouse ; non-insulin-dependent diabetes mellitus ; animal model ; insulin secretion ; isolated islets.

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The NSY (Nagoya-Shibata-Yasuda) mouse was established as an inbred strain of mouse with spontaneous development of diabetes mellitus, by selective breeding for glucose intolerance from outbred Jcl:ICR mice. NSY mice spontaneously develop diabetes mellitus in an age-dependent manner. The cumulative incidence of diabetes is 98 % in males and 31 % in females at 48 weeks of age. Neither severe obesity nor extreme hyperinsulinaemia is observed at any age in these mice. Glucose-stimulated insulin secretion was markedly impaired in NSY mice after 24 weeks of age. In contrast, fasting plasma insulin level was higher in male NSY mice than that in male C3H/He mice (545 ± 73 vs 350 ± 40 pmol/l, p 〈 0.05, at 36 weeks of age). Pancreatic insulin content was higher in male NSY mice than that in male C3H/He mice (76 ± 8 vs 52 ± 5 ng/mg wet weight, p 〈 0.05, at 36 weeks of age). Morphologically, no abnormal findings, such as hypertrophy or inflammatory changes in the pancreatic islets, were observed in NSY mice at any age. These data suggest that functional changes of insulin secretion in response to glucose from pancreatic beta cells may contribute to the development of non-insulin-dependent diabetes mellitus (NIDDM) in the NSY mouse. Although insulin sensitivity was not measured, fasting hyperinsulinaemia in NSY mice suggests that insulin resistance may also contribute to the pathogenesis of NIDDM. Since these findings are similar to the pathophysiologic features of human NIDDM patients, the NSY mouse is considered to be useful for investigating the pathogenesis and genetic predisposition to NIDDM. [Diabetologia (1995) 38: 503–508]

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00400717

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext