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  • 81.40 Z  (1)
  • Cerebral blood flow  (1)
  • Noradrenaline  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 63 (1996), S. 93-101 
    ISSN: 1432-0630
    Keywords: 81.40 Z ; 81.60 Z ; 61.70
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Holes drilled in metals and silicon using different short-pulse lasers (copper vapour, Nd : YLF and titanium: sapphire) were characterized under optical and electron microscopy. The aim was to analyze and compare the thermal and mechanical effects on materials induced by laser drilling with a wide range of pulse widths (50 ns to 200 fs) and power densities (108 W/cm2 to 1015 W/cm2). Heat affected structural zones around micro-holes drilled in cold-rolled copper were revealed by analyzing ion-polished hole sections in the scanning electron microscope using electron channelling contrast. The heat affected zones were found to have a maximum width of 5 μm to 10 μm, independent of the duration of the pulses. Mechanically and thermally induced deformations and slip phenomena, including “prismatic punching”, were observed in laser-drilled molybdenum monocrystals. The dislocation arrangement which developed during laser drilling of silicon monocrystals was visualized by transmission electron microscopy. The microscopic studies showed that for percussion drilling in the high fluence range characterized by high ablation rates of a few micrometres per pulse the use of shorter pulses (τH 〈 50 ns) did not lead to any appreciable reduction in the melt component, material re-deposition or thermal load on the wall of the hole. In addition, the increasing mechanical loads on the material due to the higher pressure in the drill channel becomes a limiting factor for the precision of the processing.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 150 (1991), S. 503-506 
    ISSN: 1432-1076
    Keywords: Dopamine infusion ; Newborn infants ; Plasma catecholamines ; Noradrenaline ; Adrenaline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Newborn infants (21 preterm and 13 term) received dopamine infusions at a low (2.5–3.4 μg/kg per min) and/or high (5–10 μg/kg per min) infusion rate and changes in plasma catecholamines were monitored. The mean baseline values for dopamine, noradrenaline and adrenaline were between 240 and 560, 125 and 144 and 62 and 82 pg/ml, respectively. During low-rate infusion of dopamine, there was a significant increase in plasma dopamine (20–100fold), noradrenaline (three- to five-fold) and adrenaline (threefold). Administration of dopamine at the high rate resulted in an even larger increase in the plasma catecholamines (dopamine, 100–300fold; noradrenaline, seven- to eightfold; adrenaline, four- to sixfold). In a double-log plot, there was a highly significant correlation between the plasma concentrations of dopamine and noradrenaline (r=0.77;P〈0.001). In conclusion, infusion of dopamine in term and preterm newborn infants is accompanied by an enhanced sympatho-adrenal tone which may contribute to the cardiovascular effects of dopamine in these patients.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 18 (1980), S. 39-47 
    ISSN: 1741-0444
    Keywords: Cerebral blood flow ; Isotope clearance ; Noninvasive technique
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The validity of atraumatic measurements of regional cerebral blood flow (r.c.b.f) by intravenous injection of Xenon 133 has been studied in 17 patients with cerebrovascular diseases. The results were directly compared with those obtained in the same subjects using the intracarotid-injection method. Clearance curves obtained by the intravenous method were analysed by means of a bicompartmental model of blood circulation corrected for recirculation of the tracer. Use of different modes of intravenous injection and systematic analysis of the portion of the clearance curve usable for estimation of regional cerebral blood flow enabled the authors to define the optimal conditions for measurement of r.c.b.f. in subjects with cerebrovascular disorders. A predominant source of error was found to be the difficulty in defining the exact instant when clearance begins. As a result, the best conditions were as follows: slow injection (1 min) of tracer and analysis of the portion of clearance curve between 3 and 11 min after the beginning of the clearance. Under these conditions this atraumatic method is as precise in subjects with cerebrovascular disease as in those with normal cerebral circulation.
    Type of Medium: Electronic Resource
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