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  • 1
    ISSN: 1435-2451
    Keywords: Arteriosclerosis ; Surgical treatment ; Late results ; Arteriosklerose ; Chirurgische Behandlung ; Spatergebnisse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Spatergebnisse der rekonstruktiven Arterienchirurgie werden an 5245 operierten Kranken der Chirurgischen Universitätskliniken Köln und München (1959–1974) dargestellt. Die Eingriffe bei cerebrovasculärer Insuffizienz (378 Kranke), renovasculärer Hypertonie (257 Kranke) and Angina intestinalis (24 Pat.) ermöglichen bei niedriger operativer Letalität and Morbidität eine Lebensverlängerung, bei Verschlüssen im Aorta-Iliaca-Bereich (2547 Pat.) and am femoro-poplitealen Abschnitt (1440 Pat.) gilt die Erhaltung der Extremität als therapeutisches Ziel. Bei peripheren (303 Pat.) and Aortenaneurysmen (296 Pat.) ist fur ein gutes Behandlungsergebnis der frühzeitige Eingriff vor dem Auftreten von Komplikationen (Thromboembolie bzw. Ruptur) Voraussetzung.
    Notes: Summary The long-term follow-up results of reconstructive vascular surgery are demonstrated in 5245 patients operated on in the University Surgical Clinics in Cologne and Munich (1959–1974). With low surgical lethality and morbidity, operative treatment of cerebrovascular insufficiency (378 patients) or renovascular hypertension (257 patients) guarantees longer survival. In cases of aorto-iliacal (2547 patients) and femoropopliteal (1440 patients) occlusion, the object of therapy is the preservation of the extremity. For good results, operative treatment of peripheral and aortic aneurysms should be performed before complications such as thromboembilism or rupture of the aneurysm occur.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-8580
    Keywords: Renal preservation ; Anaerobic ischemia ; Aerobic ischemia ; Retrograde renal O2 persufflation ; Post-ischemic renal function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Retrograde persufflation of ischemic kidneys of dogs via the renal vein with gaseous O2 was evaluated as a method of kidney preservation (retrograde aerobic ischemia) and compared to conventional ischemic storage without additional measures (anaerobic ischemia). Renal preservationin situ lasted 4 hrs at 6°C. A contralateral nephrectomy was performed before the preservation period. For retrograde aerobic ischemia the persufflation pressure was 30 mm Hg, the gas flowed off via opened capsular vessels. While dogs which had undergone renal anaerobic ischemia showed a marked temporary post-ischemic increase in renal blood flow and in the systemic blood pressure, dogs submitted to renal retrograde aerobic ischemia did not exhibit a storage induced loss of the renal vascular autoregulation. During and after retrograde aerobic ischemia the renal tissue levels of ATP, ADP, and AMP remained within normal ranges; ATP and the sum of adenine nucleotides decreased markedly during anaerobic ischemia. In both the groups a normal renal function was resumed again; but the recovery time of various parameters of renal function (clearance from inulin and PAH, urea excretion, serum concentrations of urea and creatinine) was shorter after retrograde aerobic ischemia than after anaerobic ischemia. Kidneys subjected to retrograde aerobic ischemia exhibited a better functional adaption to the contralateral nephrectomy during the 3 weeks of post-ischemic observation than kidneys stored in anaerobic ischemia.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1433-8580
    Keywords: Renal preservation ; Anaerobic ischemia ; Aerobic ischemia ; Renal O2-persufflation ; Post-ischemic renal function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In search for new techniques of renal preservation, kidneys were persufflatedin situ with gaseous O2 at a pressure of 90–100 mm Hg via their vascular system (orthograde aerobic ischemia). The results on post-ischemic function and blood flow, and on the changes in the renal tissue levels of the adenine nucleotides were compared to those obtained from kidneys ischemically stored without additional measures (anaerobic ischemia). The kidneys were stored for 4 hrs at 6°C. A contralateral nephrectomy was performed before the preservation period. All dogs subjected to renal anaerobic ischemia survived. After orthograde aerobic ischemia, 3 out of 4 dogs died from uremia within 8 days, 1 animal survived. Although the aerobic ischemic preservation resulted in the maintenance of a metabolic status characteristic for aerobiosis, post-ischemic renal function recovered too slowly and insufficiently on the average. Renal blood flow was within normal ranges after anaerobic ischemia, it was reduced to about one third of this after orthograde aerobic ischemia.
    Type of Medium: Electronic Resource
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