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  • Chemistry  (2)
  • Allosteric inhibition  (1)
  • Diabetic Macular Oedema.  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Short-wavelength sensitive visual field loss in patients with clinically significant diabetic macular oedema (1998)
    Springer
    Diabetologia 41 (1998), S. 918-928 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Perimetry ; Visual Field ; Short-Wavelength Sensitivity ; Selective Loss ; Diabetic Macular Oedema.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aim of the study was to compare the sensitivity of short-wavelength and conventional automated static threshold perimetry for the psychophysical detection of abnormality in patients with clinically significant diabetic macular oedema. The sample comprised 24 patients with clinically significant diabetic macular oedema (mean age 59.75 years, range 45–75 years). One eye of each patient was selected. Exclusion criteria included the presence of lenticular opacity. The sensitivity of the macular visual field of each patient was determined with programme 10–2 of the Humphrey Field Analyser on two occasions, using both short-wavelength and conventional stimulus parameters; the results of the second session were analysed to minimise learning effects. A pointwise horizontal hemifield asymmetry analysis was derived for short-wavelength perimetry (thereby negating the influence of pre-receptoral absorption); the pointwise pattern deviation probability plot was analysed for conventional perimetry. Abnormality was defined as 3 or more contiguous stimulus locations with negative asymmetries (short-wavelength) or reduced sensitivity values (conventional) that resulted in a statistical probability level of p less than 0.05. The fields of 8 patients were abnormal as assessed by conventional perimetry while all were classified as abnormal using short-wavelength perimetry. In the 8 patients who exhibited both abnormal conventional and abnormal short-wavelength perimetry results, the extent of field loss was generally greater using short-wavelength perimetry. The position of the localised field loss (i. e. as distinct from field loss that was generalised across the visual field) assessed by short-wavelength perimetry corresponded with the clinical mapping of the area of diabetic macular oedema but the extent of this loss was generally greater than that suggested by clinical assessment. Short-wavelength automated perimetry offers improved sensitivity for the psychophysical detection of clinically significant diabetic macular oedema. [Diabetologia (1998) 41: 918–928]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250051008
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cloning and characterisation of the adenosyl phosphosulphate kinase gene from Aspergillus nidulans (1997)
    Springer
    Current genetics 32 (1997), S. 408-412 
    Details
    ISSN: 1432-0983
    Keywords: Key words APS kinase ; ATP sulphurylase ; Aspergillus nidulans ; Allosteric inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The sD gene of Aspergillus nidulans has been cloned by heterologous screening of rationally selected cosmids. Co-transformation of the sD50 mutant JMP1 confirmed the presence of a functional gene. Sequence analysis determined this gene to be 680 bp in length, containing a 59-bp intron and encoding a protein of 206 amino acids. A protein-sequence comparison revealed a similarity to the C-terminal region of ATP sulphurylase, the sC gene product. Further sequence comparison revealed differences in a consensus sequence ATP-binding motif, indicating non-functionality of the APS kinase-like domain of ATP sulphurylase, and confirms sD as the gene encoding APS kinase in A. nidulans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050295
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Simultaneous computation of heat transfer and dispersion coefficients and thermal conductivity value in a packed bed of spheres: II. Technique of computing numerical values (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 590-592 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The method of computing the numerical values is given. It is illustrated with a simulated example to show the high accuracy that is possible, the unknowns being found to four significant figures. The only quantities required are ones that can be measured accurately: the radius of the spherical packing, its volumetric specific heat, and values of the amplitude attenuation and phase angle lag at a minimum of four finite values of the frequency.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170320
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    A method of finding simultaneously the values of the heat transfer coefficient, the dispersion coefficient, and the thermal conductivity of the packing in a packed bed of spheres: Part I. Mathematical analysis (1967)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 13 (1967), S. 678-682 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The response of a packed bed to a sine wave of temperature in a stream of fluid through it will depend upon the amount of dispersion in the resistance to transfer between fluid and solid, and the thermal properties of the soild. A method is presented that allows the effects of these three phenomena on the amplitude and phase angle to be unravelled and hence all their magnitudes to be computed simultaneously. It thus presents a way of determining these three quantities in situations where they were previously obtainable either with great uncertainty or not at all. The method requires measurements of the relative amplitudes and phase angles at three frequencies, and (preferably) at ω → 0 as well, all to be carried out with high accuracy.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690130417
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    Paper (German National Licenses)
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