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  • central composite design  (3)
  • Analytical Chemistry and Spectroscopy  (1)
  • Bronchialstent  (1)
  • 1
    ISSN: 0960-8524
    Keywords: Sclerotium rolfsii ; cellulase ; central composite design ; enzymatic hydrolysis ; hemicellulase ; medium optimization ; response surface methodology ; xylanase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Enzyme and Microbial Technology 15 (1993), S. 677-682 
    ISSN: 0141-0229
    Keywords: Thermomyces lanuginosus ; central composite design ; medium optimization ; solid-state culture ; submerged culture ; xylanase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Enzyme and Microbial Technology 15 (1993), S. 854-860 
    ISSN: 0141-0229
    Keywords: Schizophyllum commune ; central composite design ; medium optimization ; xylanase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Lungentransplantation ; Anastomosenkomplikation ; Angioplastie ; Bronchialstent ; Key words Lung transplantation ; Anastomotic complications ; Angioplasty ; Bronchial stenting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: Bronchial and arterial anastomotic stenoses are major complications after lung transplantation. Interventional techniques provide a definitive cure in certain cases. Material and methods: Three out of four patients had ischemia-related stenoses of the bronchial anastomoses postoperatively; one patient developed malacia of the bronchus main stem 1 year after transplantation. Four patients had stenoses of the arterial anastomoses, which resulted in hemodynamic instability and reduced perfusion of the graft. Results: Stent implantation in the bronchial anastomoses (n = 3) and in the main stem (n = 1) improved ventilation and oxygen saturation in all patients. The stents were incorporated by mucosal overgrowth, as demonstrated by endoscopy, as early as 6 weeks after implantation. Balloon dilatation (n = 3) and stent implantation (n = 1) were successfully performed in 4 patients with stenoses of the arterial anastomoses. The mean transstenotic pressure gradient of 9.5 mm Hg was reduced to 2.2 mm Hg after angioplasty. Lung perfusion shifted towards the grafts, as shown by 99mTc perfusion scans. Conclusion: The minimally invasive techniques of interventional radiology are very effective in the treatment of anastomotic complications after lung transplantation and may avoid surgery in certain cases.
    Notes: Zusammenfassung Komplikationen nach Lungentransplantation betreffen in erster Linie die Bronchusanastomose und die Pulmonalarterienanastomose. Sie sind ischämieinduziert oder auf chirurgisch-technische Probleme zurückzuführen. Bei 8 von 66 transplantierten Patienten traten postoperative Stenosen an der arteriellen Anastomose (n = 4) und an der Bronchusanastomose (n = 4) auf, die jeweils zu einem organ- bzw. lebensbedrohlichen Zustand der Patienten geführt hatten. Die interventionelle Behandlung war bei allen Patienten erfolgreich; 4 Patienten wurden bei Anastomosenstenose bzw. Malazie der Bronchusanastomose mit Metallstent versorgt, 4 Patienten mit Stenosierung an der Pulmonalarterienanastomose wurden einer Ballondilatation bzw. zusätzlicher Stentimplantation zugeführt. Die Indikation zur Behandlung und die Überprüfung des Dilatationsergebnisses wurde anhand der Stenosegradienten ermittelt, zur ausreichenden Erweiterung war eine Ballonkaliberstärke von 15 bis 20 mm erforderlich. Indikation zur Stentimplantation war eine elastische Instabilität bei einem Patienten. Der minimal-invasive Eingriff bei schwerkranken Patienten, die effiziente und komplikationslose Therapie und der erfolgreiche Langzeitverlauf sprechen dafür, bei Anastomosenproblemen nach Lungentransplantation interventionelle radiologische Verfahren primär einzusetzen.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0935-6304
    Keywords: Solvents and GC detectors ; Coupled HPLC-GC ; Column effluent splitter ; Di-(2-ethylhexyl) phthalate ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Introduction of solutions of up to several milliliters by on-column injection of large volumes or by coupled HPLC-GC may cause problems with GC detectors (FID, AFID, MS). For instance, dichloromethane forms large amounts of hydrochloric acid and carbon black in FIDs.A column effluent splitter was developed for keeping the major portion of the solvent vapors away from the detector; approximately 99% of the vapor is vented while the remaining 1% of vapor is used for detecting the widths of the solvent peaks. During analysis, the split ratio is reversed by a strong increase of the resistance to the gas flow through the split exit line.The system was used for the determination of di-(2-ethylhexyl)-phthalate (DEHP) in triglyceride matrices of various foods. Direct determination by HPLC is not sufficiently sensitive, whereas direct analysis by GC is hindered by the triglycerides. Solutions of fats or oils were pre-separated on a silica column using dichloro-methanelcyclohexane 1:l with addition of 0.05 % acetonitrile as eluent. The HPLC fraction containing the DEHP was transferred to GC through a loop-type interface using concurrent solvent evaporation. Detection limits were around 0.1 ppm.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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