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  • 1
    Electronic Resource
    Electronic Resource
    Successful treatment of neutropenia in T-LGL leukemia (Tγ-lymphocytosis) with granulocyte colony-stimulating factor (1994)
    Springer
    Annals of hematology 69 (1994), S. 117-119 
    Details
    ISSN: 1432-0584
    Keywords: T-LGL ; Leukemia ; G-CSF
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Severe neutropenia is a common feature in patients with T-large granular lymphocytic (LGL) leukemia. Neutropenia often causes severe infections and septicemia, thus representing a major cause of morbidity and mortality in this disease. We have treated two outpatients with T-LGL leukemia who had severe neutropenia (neutrophils 〈0.2×109/l) successfully with G-CSF (5μg/kg daily, s.c). After 10 days of treatment the neutrophil count was within the normal range and a severe oral infection healed rapidly. We conclude that G-CSF therapy is able to normalize the neutrophil count in T-LGL leukemia within a few days and that it can be used to treat severe infections in these patients even on an outpatient basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01695691
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Isolated meningeal chloroma (granulocytic sarcoma) – a case report and review of the literature (2000)
    Springer
    Annals of hematology 79 (2000), S. 459-462 
    Details
    ISSN: 1432-0584
    Keywords: Key words Chloroma ; Acute myeloblastic leukemia ; Chemotherapy ; Autologous stem cell transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Isolated chloromas (granulocytic sarcomas) are rare tumors, most of them progressing to acute myeloblastic leukemia within months. There are still no conclusive treatment strategies for this entity; however, early antileukemic chemotherapy seems to lower the probability of developing systemic disease and prolong survival. We report on a patient with isolated meningeal chloroma, primarily misdiagnosed as a high-grade Non-Hodgkin's lymphoma. Two cycles of antileukemic induction chemotherapy were administered, followed by local irradiation and intensified consolidation therapy with autologous stem cell transplantation. After 20 months, he is still in complete remission.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770000165
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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