ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Conclusions 1. The high-resolution13C NMR spectra were analyzed for 16α, 17α-cyclohexanopregnanes substituted in rings A and B by SR (R=Ph, CH2CH2SH) and S(O)Ph groups. These spectra were used to determine the position of the double bond (Δ4 or Δ5) and the position and orientation of the 3α-SR, 3β-SR, 5α-SR, and 3β-S(O)Ph substituents. 2. The α-, gb-, γ-, and δ-effects of the SR (R=Ph, CH2CH2SH) and S(O)Ph substituents on the chemical shifts of the carbon atoms of the steroid skeleton were determined and analyzed. A diastereotopic effect of the S(O)Ph group on the chemical shifts of the carbon atoms of rings A and B was discovered.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00955423
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