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  • 11
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 59 (1991), S. 2287-2289 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Basic properties of AlxGa1−xAs (x=0.2–0.7), grown by molecular beam epitaxy on 0.5°-tilted (111)B-GaAs, are studied. We have employed the wide substrate temperature, Ts, range of 540–740 °C and different As species; As4 and As2. The surface morphology has been found to depend strongly upon the As species; a specular surface morphology cannot be obtained when using As2 whereas a specular smooth surface can be obtained at high temperatures when using As4. Photoluminescence intensity of n-Al0.3Ga0.7As (Si=1×1018 cm−3) grown at low Ts (〈620–630 °C) does not depend upon the As species and is considered to be determined by defects, such as microtwins and stacking faults, which have been observed by transmission electron microscopy. At high Ts ((approximately-greater-than)650 °C) photoluminescence intensity is lower for the case of As2 than As4 and this could be due to point defects, such as As interstitials and/or antisite As (AsGa). Deep level transient spectroscopy has been measured on n-Al0.7Ga0.3As grown on (100)- and (111)B-substrates with As4.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 1718-1720 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Stable and reliable AlGaAs high power single quantum well lasers prepared by molecular beam epitaxy have been realized. We have prepared both 50-μm devices operating in multiple modes and ridge-waveguide single transverse-mode devices. Good reliability has been confirmed under the operating condition of 500 mW at 50 °C for the former type of devices and under the condition of 50 mW at 50 °C for the latter type of devices over 1000 h. These results indicate that molecular beam epitaxy is capable of making reliable high power laser diodes.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 75 (1999), S. 1839-1841 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Systematic study on the effects of the waveguide thickness Wg has been carried out for 200-μm-wide stripe separate-confinement-heterostructure lasers in the range of Wg=0.22–1.2 μm while the width of single quantum well is kept constant at 10 nm. The internal loss αi is reduced from 1.7 to 1 cm−1 when Wg is increased from 0.22 to 1.2 μm. It is shown that αi is not determined by the free-carrier absorption of clad layers, but primarily by Γ, the optical confinement factor, most probably due to scattering at the quantum well/waveguide interfaces. The external differential quantum efficiency ηd monotonically increases with Wg for pulsed operation. By contrast, ηd is maximum at Wg=0.8 μm for continuous-wave (cw) operation. Both the threshold carrier density and the threshold temperature sensitivity increases with Wg for Wg≥0.8 μm, which decreases ηd in cw operation. When 200-μm-wide devices (20%/97% coated) were life tested at 2 W and 30 °C, the median degradation rate shows a minimal value of 3×10−6 h−1 at Wg=0.8 μm, which is 7 times smaller than that at Wg=0.22 μm. The facet temperature measured by the modulation reflectance is also minimized at Wg=0.8 μm. In broad-waveguide lasers with increasing Wg, the increase in carrier overflow competes with the reduction of optical power density, and thus self-absorption in the quantum well, which determines the optimal Wg. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 732 (1994), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 732 (1994), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 47-50 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: For Coulomb excitation experiments using a γ-ray detector array, a position-sensitive particle detector system that has a good angular resolution, capability of managing a high-counting rate, robustness for a radiation damage, compactness (under 110 mm φ) and easiness of handling is necessary. For this purpose we developed a new device utilizing plastic and yttrium aluminum perovskite activated by cerium (formula YAlO3:Ce abbreviated YAP Ce) scintillators and a position-sensitive photomultiplier tube. The detector system could operate at a high-counting rate (about 105), and with a good position resolution of 0.5–1.2 mm, which was enough for Doppler correction of the γ rays. It could sustain the radiation damage caused by Coulomb excitation experiments with heavy ions for more than 50 days. The detector chamber was well fitted in the 110 mm φ diameter of the internal space of a compact γ-ray detector array, GEMINI. This was much easier to handle than the position-sensitive gas counter. In Coulomb excitation experiment utilizing this device, the nucleus 74Ge has been Coulomb excited using a Pb target. The transitional E2 matrix elements have been determined and the device has turned out to be useful in Coulomb excitation experiments with heavy-ion beams. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 17
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In0.2Ga0.8As single strained quantum well lasers with GaAs/Al0.45Ga0.55As short-period superlattice barrier (SPSB)layers have been successfully prepared using molecular beam epitaxy although a part of SPSB has been grown in the forbidden temperature region for AlGaAs, where the specular smooth bulk AlGaAs cannot be grown. The averaged AlAs mole fraction of the present SPSB is 0.25, which gives the heterobarrier height larger than that of the conventional GaAs barrier layers. The threshold temperature sensitivity factor T0 of the laser with SPSB has been measured to be as low as 240 K, which is much larger than that of 90 K in the laser with GaAs barrier layers. This improvement results from the reduction of carrier leakage from quantum well to barrier layers.
    Type of Medium: Electronic Resource
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  • 18
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. We studied the prevalence of the hepatitis C virus (HCV), human immunodeficiency virus (HIV) and GB virus C or hepatitis G virus (GBV-C/HGV), and characteristics of infections in Japanese haemophilia patients. Haemophilia patients were highly infected with HCV (88.2%) because of frequent use of unheated blood concentrates. Analysis for HCV genotypes revealed characteristics of HCV infection in haemophilia patients. Japanese haemophilia patients were highly infected with rare genotypes in Japan: genotype 1a (26.5%), genotype 3 (14.5%) and genotype 4 (2.4%). HIV infection was observed in 32.3% of haemophilia patients. HCV quasispecies (clones) and direct sequencing were investigated in patients with a single HCV genotype in the hypervariable region 1 of HCV, which resulted in a high degree of diversity. This indicates that even a single genotype of HCV might have multiple origins. GBV-C/HGV infection was noted in 20.9% of Japanese haemophilia patients. Over 40 haemophilia patients with chronic hepatitis C have been treated with interferon alpha for 6 months at total doses of 480–720 million units. About 38% showed clearance of HCV RNA from serum. Six patients with HIV infection were included in the study and they did not show eradication of HCV from the serum. This might derive from that they had high serum HCV RNA titers and genotype 1a or 1b. Histologic assessment was performed in 36 haemophilia patients with HCV. No case showed a histologically normal liver. Hepatic fibrosis in the biopsy specimens was classified into five stages of fibrosis and compared with serum hepatic fibrosis markers. Serum hyaluronic acid mostly correlated with hepatic fibrosis (γ= 0.78, P 〈 0.0001) followed by type IV collagen (γ= 0.38, P 〈 0.05). This suggests that estimation of serum fibrosis markers might be substituted for liver biopsy in haemophilia patients.
    Type of Medium: Electronic Resource
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  • 19
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We observed massive bleeding from a gastric erosion following transcatheter arterial chemoembolization (TAE) in a patient with mild haemophilia A. A 78-year-old haemophiliac (factor VIII level over 60%) received TAE with farmorubicin and spongel. Haematemesis and melena with loss of consciousness occurred 9 days after TAE, and endoscopy revealed superficial erosions with oozing. Toxic effects of the anticancer drug in conjunction with the bleeding disorder may have caused the massive bleeding. We should always consider the possibility of unexpected complications in patients with bleeding disorders; gastrointestinal bleeding can develop during treatment for liver tumours.
    Type of Medium: Electronic Resource
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  • 20
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We observed six cases of haemophiliacs with HIV-induced immunodeficiency who died from fatal liver failure despite the absence of evident cirrhosis. They all had the infection with hepatitis viruses (two patients with hepatitis B and D viruses and four patients with hepatitis C virus) and their CD4 counts were severely decreased. They were much younger than cirrhotic haemophiliacs without HIV. Their serum levels of hyaluronic acid and type IV collagen were lower than those in haemophiliacs with cirrhosis, and were normal. No patients had experienced symptoms or concomitant diseases characteristic of cirrhosis, such as ascites, jaundice, oesophageal/gastric varices or hepatocellular carcinoma, except for one case who had a history of mild ascites. The characteristics of this liver failure were different from liver failure resulting from cirrhosis caused by chronic hepatitis, which suggests liver failure that is specific to patients with immunodeficiency. This kind of liver failure can be a factor threatening survival in patients with HIV infection and with hepatitis virus co-infection in an immunodeficient state.
    Type of Medium: Electronic Resource
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