Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    The @Journal of Steroid Biochemistry and Molecular Biology 49 (1994), S. 39-42 
    ISSN: 0960-0760
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Rock mechanics and rock engineering 6 (1974), S. 91-100 
    ISSN: 1434-453X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Description / Table of Contents: Summary Are there Connexions Between Earthquakes and the Frequency of Rock Bursts in the Mine of Bleiberg Observations, that were done in the mine of Bleiberg, allow the conclusion, that the same stresses in the earth's crust, which cause earthquakes cause higher frequencies of rock bursts, to. Specially the area of earthquakes around the Mediterranean has effects on Bleiberg. But also other parts of the earth's crust in particular those of the Caribbean area, seem to have their effects. Effects caused by earthquakes of the South-American Pacific-Coast could not be derived from our records.
    Abstract: Résumé Relations entre des tremblements de terre et des coups de rupture de roche Des observations faites durant des années dans la mine de Bleiberg on permis de conclure, que les contraintes dans l'écorce terrestre qui provoque des séismes suscitent également une augmentation de la fréquence des coups de rupture de roche. En particulier, Bleiberg est sous l'influence de la zone sismique de la région de la Méditerranée, mais il semble, que d'autres régions de l'écorce terrestre, par exemple celles de la région caraibe, ont une influence sur la région mentionnée. Par contre selon les enregistrements effectués on a pas pu constaté une influence des séismes de la côte sud-américaine du Pacifique sur cette région.
    Notes: Zusammenfassung Gibt es Zusammenhänge zwischen Erdbeben und Gebirgsschlaghäufungen im Bergbau Bleiberg Langjährige Beobachtungen beim Bergbau Bleiberg lassen den Schluß zu, daß dieselben Spannungen in der Erdkruste, welche Erdbeben auslösen, auch Gebirgsschlaghäufungen hervorrufen. Im besonderen wirkt sich auf Bleiberg offenbar die durch den Mittelmeerraum führende Erdbebenzone aus. Aber auch Unruhen anderer Teile der Erdkruste, so jene des Karibischen Raumes, scheinen Einfluß zu haben. Von Erdbeben der südamerikanischen Pazifikküste konnte nach unseren Aufzeichnungen kein Einfluß abgeleitet werden.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 13
    ISSN: 1432-1440
    Keywords: Cancer-associated hypercalcemia ; Bisphosphonate ; Pamidronate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary After a 48-hour rehydration period 28 of 31 patients with cancer-associated hypercalcemia (serum calcium ≥2.8 mmol/1) were treated intravenously with the bisphosphonate pamidronate. In three patients fluid repletion with 0.9% saline solution had already normalized serum calcium levels. Pamidronate was given in a single infusion on day 0, the dose of pamidronate adapted to the severity of hypercalcemia. If the serum calcium concentration was ≥2.8 mmol/1 on day 3, application of pamidronate was repeated. In all patients normocalcemia was restored; mean serum calcium decreased from 3.2±0.35 on day 0 to 2.15±0.32 on day 12. Hypercalcemia recurred in 11 patients, seven of these underwent pamidronate treatment according to the same therapeutical regimen. Normal calcium levels were attained in five cases. Side effects were of minor gravity:brief hyperthermia occurred in four patients and transient, asymptomatic hypocalcemia was noticed in nine cases.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 14
    ISSN: 1432-1912
    Keywords: Key words Nitric oxide ; Cyclic GMP ; Calcium ; Hirudin ; Molsidomine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the effects of L-arginine (L-ARG), the precursor of endogenous NO, on platelet aggregation and thromboxane A2 formation in vivo and in vitro. Human platelet-rich plasma (PRP) was anticoagulated with citrate (which decreases extracellular Ca2+) or with recombinant hirudin (which does not affect extracellular Ca2+). Two groups of 10 healthy male volunteers received intravenous infusions of L-ARG (30 g or 6 g, 30 min) or placebo. Blood was collected immediately before and at the end of the infusions for aggregation by ADP or collagen. Infusion of L-ARG inhibited ADP-induced aggregation in PRP anticoagulated with citrate by 37.5 ± 6.3% (P 〈 0.05). In PRP anticoagulated with hirudin, aggregation was inhibited by 33.6 ± 16.0% (P 〈 0.05). L-ARG infusion also inhibited platelet TXB2 formation and slightly, but not significantly decreased the urinary excretion rate of 2,3-dinor-TXB2; cGMP concentrations in PRP were significantly elevated during L-arginine infusion. In vitro preincubation with L-ARG (10 μM–2.5 mM) inhibited platelet aggregation in PRP anticoagulated with r-hirudin, but not citrate. This effect was stereospecific for L-arginine, as D-arginine had no effect. It was dependent upon NO synthase activity, as indicated by increased cGMP levels in PRP. Moreover, both the NOS inhibitor L-NMMA and the inhibitor of soluble guanylyl cyclase ODQ antagonized the effects of L-ARG. Haemoglobin, an extracellular scavenger of NO, partly antagonized the antiplatelet effects of L-ARG. 8-Br-cyclic GMP and the exogenous NO donor linsidomine inhibited aggregation in PRP anticoagulated with citrate or r-hirudin. The inhibitory effects of L-ARG on platelet aggregation in vitro were paralleled by increased cyclic GMP levels; L-ARG also inhibited platelet TXB2 formation in PRP anticoagulated with r-hirudin, but not citrate. We conclude that the L-arginine/NO pathway is present in human platelets as a Ca2+-dependent anti-aggregatory pathway. In vivo the formation of NO from L-ARG by endothelial cells may contribute to the platelet-inhibitory effects of L-ARG. NO-releasing compounds like linsidomine inhibit platelet aggregation in vitro independent of extracellular Ca2+.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 15
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 3285-3294 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 16
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron Letters 31 (1990), S. 4113-4116 
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 17
    Electronic Resource
    Electronic Resource
    Springer
    International review of education 28 (1982), S. 29-51 
    ISSN: 1573-0638
    Source: Springer Online Journal Archives 1860-2000
    Topics: Education
    Description / Table of Contents: Zusammenfassung In Anbetracht der hohen Kosten und zum Teil enttäuschenden Ergebnisse, die mit dem massiven Ausbau des allgemeinbildenden Schulwesens in Entwicklungs- und Schwellenländern verbunden sind, wird der Frage nachgegangen, inwieweit sich für Arbeiter in brasilianischen Industriezentren außerschulische Bildungs- und Ausbildungsanstrengungen über den Erhalt eines entsprechenden Arbeitsplatzes auszahlen. Informationen über den Bildungs- und Ausbildungsgang von 149 Bewerbern um industrielle Arbeitsplätze in João Pessoa und Salvador werden zum Erfolg der Bewerbungen diskriminanzanalytisch in Beziehung gesetzt. Dabei zeigt sich an beiden Orten, daß formale Schulbildung wohl die beruflichen Erwartungen der Arbeiter erhöht, nicht aber mit einer höheren Einstellungswahrscheinlichkeit einhergeht. Die Teilnahme an außerschulischen Bildungsmaßnahmen kovariiert hingegen bei den Facharbeitern positiv mit den Beschäftigungschancen, und zwar je nach Kontext aus unterschiedlichen Gründen: im industriell noch kaum entwickelten João Pessoa sind Programme, die keinen direkten Bezug zur angestrebten Position erkennen lassen, anscheinend ebenso wertvoll bei der Arbeitsuche wie beruflich einschlägige Kurse; dieser Befund verweist für den Kontext beginnender Industrialisierung auf die ökonomische Bedeutung, die sich mit der Teilnahme an Kursen außerhalb der Schule verbindet. Im wirtschaftlich höher entwickelten Salvador ist jedoch ein positiver Einfluß auf die Einstellungswahrscheinlichkeit nur noch für die außerschulische Berufsausbildung nachweisbar; hier setzen sich demnach an nutzbaren Fertigkeiten orientierte Entscheidungskriterien durch, die auch in westlichen Ländern gelten.
    Abstract: Résumé Les auteurs de cet article, prenant en considération le coût élevé et les résultats souvent décevants de l'extension massive de l'éducation générale dans les pays en développement, examinent jusqu'à quel point l'éducation extra-scolaire et les cours de formation aident les travailleurs des centres industriels brésiliens à obtenir un emploi. L'information a été fournie grâce à une analyse discriminante qui a établi un rapport entre l'éducation et la formation de 149 postulants à des emplois dans l'industrie à João Pessoa et à Salvador, et les résultats positifs de leurs demandes. Il est montré que si l'éducation scolaire formelle dans les deux villes suscite des espoirs professionnels chez les travailleurs, elle ne coïncide pas avec une probabilité supérieure d'embauche. Par ailleurs, la participation à l'education extra-scolaire ou à la formation exerce une influence positive sur les chances d'emploi, pour diverses raisons, selon le contexte. A João Pessoa où l'industrie en est encore aux premiers stades du développement, des programmes qui paraissent n'avoir aucune relation directe avec l'emploi convoité semblent se révéler aussi utiles dans la recherche d'un emploi que des cours spécifiquement professionnels. Ceci démontre l'importance économique des cours extra-scolaires. Toutefois, à Salvador, qui est économiquement beaucoup plus développé que João Pessoa, seule la formation professionnelle extra-scolaire paraît exercer une influence positive sur les chances d'emploi. Là, apparemment, les critères de la décision prennent davantage en considération les compétences professionnelles, à l'instar des pays occidentaux.
    Notes: Abstract In view of the high cost and the often disappointing results achieved by the massive extension of general education in developing countries, this article investigates the extent to which out-of-school education and training courses assist workers in Brazilian industrial centres in obtaining employment. By discriminant analysis, information on the education and training of 149 applicants for industrial jobs in João Pessoa and Salvador is related to the success rate of their applications. It is shown that, while formal school education raises the vocational expectations of the workers in both towns, it does not coincide with a higher probability of securing employment. On the other hand, participation in out-of-school education or training correlates positively with employment opportunities, for different reasons according to the context. In João Pessoa, where industry is only in the early stages of development, programmes which appear to have no direct relation to the hoped-for job seem to be as useful in the search for employment as specific professional training courses. This indicates the economic importance of participation in out-of-school courses. In Salvador, however, which is economically more highly developed, out-of-school vocational training alone appears to have a positive influence on the chances of finding employment. Apparently, decision criteria here are oriented more to consideration of usable skills, as they are in Western countries.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 18
    Electronic Resource
    Electronic Resource
    Springer
    International review of education 28 (1982), S. 279-285 
    ISSN: 1573-0638
    Source: Springer Online Journal Archives 1860-2000
    Topics: Education
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 19
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 102 (1982), S. 289-299 
    ISSN: 1432-1335
    Keywords: Metastatic breast cancer ; Combination cytotoxic chemotheraphy ; Stratification parameters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary One hundred seventy-five patients with metastatic breast cancer, treated with a combination chemotherapy (Cooper regimen), were analyzed retrospectively to identify the value of the traditional prognostic parameters (disease-free interval; menopausal status; dominant site of metastatic lesion) for the stratification of patients before randomization. Response rate and survival time were not significantly affected by the disease-free interval and menopausal status. A significant difference was detected among the three categories total extent of disease (according to Swenerton) was found to be the most important factor for predicting response and survival time after combination cytotoxic treatment. The differences between the dominant size of metastatic disease are mainly influenced by different size of metastatic spread. Therefore, there is found a significant correlation between the different types of dominant lesions and total extent of disease. In conclusion, the particular sites of metastatic spread seem to be of less importance than overall extent of disease in predicting the outcome. A critical evaluation of the three traditional stratification parameters and introduction of a semiquantitative estimation of total tumor burden as a new stratification parameter seems to be necessary when planning and comparing future trials.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...