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  • 11
    Electronic Resource
    Electronic Resource
    Titanium Riechert head ring for MR Stereotaxy (1993)
    Springer
    Acta neurochirurgica 121 (1993), S. 82-85 
    Details
    ISSN: 0942-0940
    Keywords: Stereotactic surgery ; magnetic resonance imaging ; radiosurgery ; treatment planning ; instrumentation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Magnetic Resonance has become the preferred neuro-imaging modality. To fully take advantage of the high anatomical resolution the Riechert stereotactic system was adapted for use in Magnetic Resonance Stereotaxy. The head ring which until recently was made of an aluminum alloy has been replaced by an unsegmented head ring of pure titanium without changing the dimensions and fixation mode. No significant misregistration due to eddy currents has been noticed. Minor distortion induced by the titanium head ring can be corrected mathematically. Thus the geometric information is limited only by the pixel resolution of the MR image.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01405188
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  • 12
    Electronic Resource
    Electronic Resource
    Functional neuroimaging in the assessment of CNS neoplasms (1997)
    Springer
    European radiology 7 (1997), S. S209 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Magnetic resonance imaging ; Brain tumours ; Perfusion imaging ; Diffusion imaging ; Chemical shift imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Assessment of CNS neoplasms has focused traditionally on morphological analysis. Recent developments in MR sequence design now enable functional assessments. T1-weighted, as well as T2*-weighted, dynamic, gadolinium-enhanced, imaging can be used for assessment of vascularisation, permeability, and microcirculation of CNS neoplasms. Characterisation of cerebrovascular blood flow is possible using dynamic MR angiography, while neurofunctional imaging enables visualisation of local alterations in neuronal activity in stimulated cortical areas. Diffusion-weighted imaging can be used for improved delineation of neoplasms, while chemical shift imaging allows metabolic mapping of lesions and surrounding tissues. Implementation of these techniques can improve characterisation, information for therapy, planning and prognosis in clinical imaging of CNS neoplasms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00006894
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  • 13
    Electronic Resource
    Electronic Resource
    MR Angiography: clinical applications in thoracic surgery (1992)
    Springer
    European radiology 2 (1992), S. 214-222 
    Details
    ISSN: 1432-1084
    Keywords: MR angiography ; Bronchogenic carcinoma ; Thoracic surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract MR angiography (MRA) is a promising completion of MR imaging in the preoperative assessment of pulmonary and mediastinal tumours. Scan acquisition was done by sequential FLASH 2D angiograms (TR = 30 ms, TE = 10 ms, FA = 30°), one section per breathhold, section thickness 5 mm with 1 mm overlap between sequential sections. An automated control procedure allowed individiual continuation of the examination. Postprocessing by a maximum-intensity-projection algorithm using angiograms of interest (AOI) resulted in 3D reconstructions illustrating vascular anatomy and avoiding superimposition. This technique was evaluated in a prospective study of 15 patients with malignant intrathoracic tumours. The results were validated by conventional angiographic procedures such as pulmonary angiography, digital subtraction angiography or cavography. Complementing spin-echo (SE) imaging, MRA provided diagnostic information about vessel displacement, stenosis and perfusion defects due to space-occupying lesions. Thus MRA was helpful in planning thoracic surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00595833
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  • 14
    Electronic Resource
    Electronic Resource
    A 3D T1-weighted gradient-echo sequence for routine use in 3D radiosurgical treatment planning of brain metastases: first clinical results (1995)
    Springer
    European radiology 5 (1995), S. 19-25 
    Details
    ISSN: 1432-1084
    Keywords: Radiosurgery ; MPRAGE ; Spin echo ; Metastases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors report on a 3D sequence for MRI of the brain and its application in radiosurgical treatment planning of 35 brain metastases. The measuring sequence, called magnetization — prepared rapid gradient echo (MPRAGE), was compared with 2D T1-weighted spin-echo (SE) sequences following intravenous contrast-medium application in 19 patients with brain metastases. The average diameter of all lesions was similar in both sequences, with 16.8 and 17.0 mm for SE and MPRAGE, respectively. Target point definition was equal in 29 metastases, and in 6 cases superior on MPRAGE, due to better gray-white matter contrast and increased contrast enhancement. In cases of bleeding metastases there was improved depiction of internal structures in 3D MRI. Postprocessing of 3D MPRAGE data created multi-planar reconstruction along any chosen plane with isotropic spatial resolution, which helped to improve radiosurgical isodose distribution in 4 cases when compared to 2D SE. However, sensitivity of 3D MPRAGE to detect small lesions (〈 3 mm) was decreased in one patient with more than 50 metastases. We conclude that 3D gradient-echo (GE) imaging might be of great value for radiosurgical treatment planning, but does not replace 2D SE with its current parameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00178075
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  • 15
    Electronic Resource
    Electronic Resource
    Morphologische MR-Bildgebung mit T1-gewichteten Sequenzen zur radiotherapeutischen Zielvolumendefinition von intrakraniellen Tumoren Vergleich von FLASH-, Turbo-FLASH- und SE-Sequenzen (1997)
    Springer
    Der Radiologe 37 (1997), S. 243-250 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter FLASH ; Turbo-FLASH ; Spinecho ; Bestrahlungsplanung ; Key words Flash ; Turbo-Flash ; Spin-echo ; High-precision radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Introduction: The goal of this study was to compare contrast-enhanced T1-weighted Flash and Turbo-Flash sequences with conventional spin-echo sequences as a basis for planning high-precision radiotherapy. Methods: A total of 25 consecutive patients with different intracranial tumors and a disrupted blood-brain barrier were studied. T1-weighted Flash, Turbo-Flash and conventional spin-echo images were evaluated after controlled 30-s infusion of 0.1 mmol/kg body weight of Gd-DTPA. The evaluation of the three sequences included the measurement of the signal- and contrast-to-noise ratios, the visual inspection of the tumors and artifacts, and the measurement of tumor size. Results: The signal- and contrast-to-noise ratios were significantly (P 〈 0.05–0.01) lower for Flash and Turbo-Flash than for conventional spin-echo sequences. However, visual inspection of the contrast-enhancing tumors revealed in 23 and 24 of 25 lesions on Flash and Tu-rbo-Flash images, respectively, good or very good tumor visibility when compared with conventional spin-echo images with a reduction of imaging time by a factor of 7–8. Flash and Turbo-Flash sequences were more prone to susceptibility artifacts, conventional spin-echo sequences more to pulsation artifacts in the posterior fossa. Tumor sizes were comparable in all three techniques. Conclusion: At present, conventional spin-echo images are superior to fast Flash and ultrafast Turbo-Flash sequences as a basis for accurate target volume definition in high-precision radiotherapy. However, fast Flash and Turbo-Flash images may be a practicable alternative to conventional spin-echo images for tumors in the posterior fossa or in patients unable to tolerate a stereotactic fixation device. Despite some limitations, Turbo-Flash sequences enable fast dynamic MR imaging combined with an acceptable morphology, which may be sufficient for target volume planning in high-precision radiotherapy.
    Notes: Zusammenfassung Ziel dieser Studie ist ein Vergleich der qualitativen und quantitativen Eigenschaften von schnellen T1-gewichteten FLASH- und ultraschnellen Turbo-FLASH-Sequenzen mit konventionellen Spinecho(SE)-Sequenzen als Grundlage der morphologischen Zielvolumendefinition einer intrakraniellen Präzisionsbestrahlung. Insgesamt wurden 25 Patienten mit verschiedenen intrakraniellen Tumoren, die mit einer Störung der Blut-Hirn-Schranke (BHS) einhergingen, mit der MRT im Rahmen einer Planung für eine stereotaktische 3D-Bestrahlung untersucht. Die qualitative Bildauswertung umfaßte die Bildqualität, Tumorsichtbarkeit und Bildartefakte, die quantitative Auswertung die Bestimmung des Signal- und Kontrast-Rausch-Quotienten und der Tumorgröße. Die Ergebnisse zeigen, daß konventionelle SE-Sequenzen derzeit am besten zur morphologischen Darstellung von Hirntumoren mit einer BHS-Störung und somit zur präzisen Festlegung des Zielvolumens im Rahmen einer Präzisionsbestrahlung geeignet sind. Demgegenüber bieten sich schnelle und ultraschnelle Gradientenecho(GE)-Sequenzen aufgrund der gering ausgeprägten Pulsationsartefakte insbesondere bei Patienten mit Tumoren in der hinteren Schädelgrube an sowie bei Patienten, die ein stereotaktisches Fixationssystem schlecht tolerieren. Sollen darüber hinaus funktionelle Informationen über das Tumorstroma (z. B. Tumorperfusion, vaskuläre Permeabilität) für die Bestrahlungsplanung oder die Therapieverlaufskontrolle gewonnen werden, so bieten Turbo-FLASH-Sequenzen neben einer hohen zeitlichen Auflösung eine ausreichend gute Gewebedarstellung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050206
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  • 16
    Electronic Resource
    Electronic Resource
    Bildorientierte Planung minimal-invasiver konformierender Bestrahlungsverfahren im Kopf-Hals-Bereich (1996)
    Springer
    Der Radiologe 36 (1996), S. 732-736 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter 3D-Bestrahlungsplanung ; Minimal-invasive Verfahren ; Konformierende Bestrahlung ; Bildkorrelation ; Stereotaxie ; Radiochirurgie ; Key words 3-D planning of radiation treatment ; Minimally invasive procedures ; Conformal radiation ; Image correlation ; Stereotaxy ; Radiosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Modern imaging techniques are a substantial part of treatment planning for minimally invasive radiotherapeutic procedures. The aim is three-dimensional assessment of the target volume and adjacent critical structures. In this paper, we report on our clinical experience with a precise system for stereotactic image correlation. Hereby, the advantages of each imaging modality can be combined. Precise immobilization of the patient is a prerequisite. The immobilization method has an accuracy of less than 1 mm. This method was evaluated in a clinical study in which a tumor control rate of 93 % was achieved in patients with brain metastases after stereotactic single high dose radiotherapy. This indicated the excellent reliability of this treatment planning method. The integration of functional image information, such as blood flow or activation of cerebral cortical areas, will be evaluated in the future.
    Notes: Zusammenfassung Die modernen bildgebenden Verfahren spielen eine wichtige Rolle bei der Planung minimal-invasiver Bestrahlungsverfahren. Ziel ist die präzise dreidimensionale (3D-) Erfassung des Zielvolumens und der umgebenden kritischen Strukturen. In diesem Beitrag werden Verfahren zur präzisen stereotaktischen Bildkorrelation für die Bestrahlungsplanung beschrieben. Durch diese Technik können die Vorzüge der einzelnen bildgebenden Verfahren kombiniert werden. Die reproduzierbare Lagerung ist hierfür eine Grundvoraussetzung. Das beschriebene Immobilisationsverfahren hat eine Genauigkeit von weniger als 1 mm. Der klinische Einsatz bei der stereotaktischen Einzeithochdosisbestrahlung, der sog. Radiochirurgie, bei Patienten mit Hirnmetastasen zeigte eine Tumorkontrollrate von 93 % und belegt damit die Zuverlässigkeit der Methode. Es muß in Zukunft evaluiert werden, wie auch funktionelle Meßgrößen in die Bestrahlungsplanung einbezogen werden können.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050135
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  • 17
    Electronic Resource
    Electronic Resource
    Funktionelle MR-Urographie bei Patienten mit Nierentransplantaten (1997)
    Springer
    Der Radiologe 37 (1997), S. 233-238 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Magnetresonanztomographie ; Nierentransplantate ; Kontrastmittel ; Urographie ; Key words Magnetic resonance imaging ; Renal transplants ; Contrast media urography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: To assess the value of functional magnetic resonance urography for the noninvasive postoperative evaluation of renal transplants. Methods: A saturation inversion projection sequence allows the selective imaging of strongly T 1 weighted signal from the MR contrast agent. A coronal slab leads to images comparable to conventional urography which can be acquired as a sequence with four images per minute. Results: 15 patients with urologic questionable findings after renal transplantation were studied. FMRU revealed in 6 patients normal findings, in 6 moderate dilatation of the renal pelvis without any urodynamic relevant obstruction. 3 pathologic findings, ureteral leak, ureteropelvic-junction obstruction and ureteral stenosis were diagnosed and consequently surgically treated. The imaging quality in all studies was diagnostic and urologically relevant. Conclusion: FMRU can be used as a noninvasive technique for the assessment of renal transplant in cases with suspicion of complication in the excretory system.
    Notes: Zusammenfassung Fragestellung: Läßt sich die funktionelle Magnetresonanzurographie (FMRU) zur nichtinvasiven Diagnostik im postoperativen Verlauf von Nierentransplantaten einsetzen? Methodik: Mit Hilfe einer Saturation-Inversion-Projektionstechnik kann eine selektive Darstellung der durch das Kontrastmittel stark verkürzten T 1-gewichteten Signalanteile erreicht werden. Durch koronare Schichtführung entstehen Bilder vergleichbar mit einer konventionellen Urographie, die als Sequenz von 4 Bildern pro Minute aufgenommen werden. Ergebnisse: 15 Patienten mit urologisch abklärungsbedürftigen Befunden nach Nierentransplantation wurden untersucht. Mit der FMRU konnte bei 6 Patienten ein unauffälliger Befund, bei 6 eine diskrete Dilatation des Nierenbeckenkelchsystems ohne urodynamisch relevante Abflußbehinderung nachgewiesen werden, jeweils eine Harnleiterleckage, eine Harnleitermündungsstenose und eine Harnleiterabgangsenge wurden diagnostiziert und daraufhin operativ saniert. Die Abbildungsqualität war bei allen Untersuchungen diagnostisch wegweisend und urologisch relevant. Schlußfolgerung: Die FMRU kann als nichtbelastende Methodik zur Abklärung des ableitenden Hohlsystems bei Verdacht auf Transplantatkomplikationen diagnostisch aussagekräftig eingesetzt werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050204
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  • 18
    Electronic Resource
    Electronic Resource
    Assessment of hemodynamic changes in patients with renal artery stenosis by means of the cine MR phase-contrast technique (1997)
    Springer
    Der Radiologe 37 (1997), S. 651-662 
    Details
    ISSN: 1432-2102
    Keywords: Key words Magnetic resonance • Flow dynamics • Renal artery stenosis ; Schlüsselwörter Magnetresonanztomographie • Hämodynamik • Nierenarterienstenose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ziel der Untersuchung war die Beurteilung der Hämodynamik bei Nierenarterienstenosen mittels Cine-MR-Phasenkontrastflußmessungen. In einem Hundemodell wurde die Cine-MR-Flußmessung validiert, indem für unterschiedliche Stenosegrade Vergleichsmessungen mit einer invasiven Transitzeit-Ultraschallreferenztechnik durchgeführt wurden. EKG-getriggerte MR-Flußkurven wurden bei 28 Patienten in 56 Nierenarterien mit einer Zeitauflösung von mindestens 32 ms aufgenommen. Alle Nierenarterienstenosen wurden mittels digitaler Subtraktionsangiographie gesichert. Störungen in der renalen Hämodynamik wurden anhand der berechneten MR-Flußkurven mit Hilfe der Parameter „Mittelfluß“, „maximale Geschwindigkeit“ und „Zeit zum systolischen Maximum“ erfaßt. Anhand der MR-Flußparameter ließen sich hochgradige Stenosen über 50 % (n = 23) mit einer Sensitivität von 100 % und einer Spezifität von 94 % im Vergleich zur DSA erkennen. Zwischen nicht stenosierten Gefäßen (n = 19) und allen Stenosen (n = 37) konnte mit einer Sensitivität von 87 % und einer Spezifität von 100 % differenziert werden. Die Beurteilung von EKG-getriggerten MR Flußkurven ermöglicht eine nichtinvasive Einstufung der hämodynamischen Signifikanz von Nierenarterienstenosen und erlaubt so wichtige funktionelle Aussagen in Ergänzung zur Morphologie der Stenose.
    Notes: Summary Purpose: To evaluate the use of high-temporal resolution cine MR phase-contrast flow measurements for assessment of flow dynamics in renal artery stenosis (RAS). Material and methods: In a dog model, cine MR flow measurements were validated by comparing the MR flow data to an invasive transit-time ultrasound reference technique for different degrees of RAS. Cardiac-gated MR flow curves were recorded in 56 renal arteries of 28 patients with a temporal resolution of at least 32 ms. In all cases RAS was confirmed by digital subtraction angiography (DSA). Abnormalities of flow dynamics were assessed in the calculated flow curves using the MR parameters mean flow, maximum velocity, and time to systolic maximum. Results: By means of the MR blood flow parameters high-grade stenoses ( 〉50 %, n = 23) were detected with sensitivity of 100 % and specificity of 94 % with reference to DSA. The overall differentiation between stenoses (n = 37) and non-stenosed vessels (n = 19) revealed a sensitivity of 87 % and a specificity of 100 %. Conclusion: Analysis of cardiac-gated MR flow curves provides a non-invasive method to assess the hemodynamic significance of RAS and thus allows a functional evaluation in relation to the morphologic characteristics of the stenosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050267
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  • 19
    Electronic Resource
    Electronic Resource
    Improved target volume definition in radiosurgery of arteriovenous malformations by stereotactic correlation of MRA, MRI, blood bolus tagging, and functional MRI (1996)
    Springer
    European radiology 6 (1996), S. 38-45 
    Details
    ISSN: 1432-1084
    Keywords: Magnetic resonance angiography ; Arteriovenous malformations ; Radiosurgery ; Image correlation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this methodological paper the authors report the stereotactic correlation of different magnetic resonance imaging (MRI) techniques [MR-angiography (MRA), MRI, blood bolus tagging (STAR), and functional MRI] in 10 patients with ce rebral arteriovenous malformations (AVM) and its application in precision radiotherapy planning. The patient's head was fixed in a stereotactic localization system that is usable at the MR and the linear accelerator installations. Byphantom measurements different materials (steel, aluminium, titanium, plastic, wood, ceramics) used for the stereotactic system were tested for mechanical stability and geometrical MR image distortion. All metallic stereotactic rings (closed rings made of massive metal) led to a more or less dramatic geometrical distortion and signal cancellation in the MR images. The best properties —nearly no distortion and high mechanical stability are provided by a ceramic ring. If necessary, the re-maining geometrical MR image distortion can be “corrected” reducing displacements to the size of a pixel) by cal culations based on modelling the distortion as a fourth-order two-dimensional polynomial. Using this method multimodality matching can be performed automatically as long as all images are acquired ill the same examination and the patient is sufficiently immobilized. Precise definition ol the target volume could be performed by the radiotherapist either directly in MR images or in calculated projecon MR angiograms obtained by a maximum-intensity projection algorithm. As a result, information about the hemodynamics of the AVM was provided by a three-dimensional (3D) phase-contrast flow measurement and a dynamic MRA with the STAR technique leading to an improved definition of the size of the nidus, the origin of the feeding arteries, and the pattern of the venous drainage. In addition functional MRI was performed in patients wit lesions close to the primary motor cortex area leading to an improved definition of structures at risk for high-dose application in radiosurgery. The differnet imaging techniques of MR provide a sensitive, noninvasive, 3D method for de fining target volume, critical structures, and for calculating dose distributions for radiosurgery of cerebral arteriovenous malformations, because dose calculation of radiosurgery at sufficient accuracy can be based on 3D MR data of the geometrical conformation of the patient's head.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00619950
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  • 20
    Electronic Resource
    Electronic Resource
    Darstellung des Blutflusses in den Gebärmutterarterien und im normalen sowie malignen Gebärmuttergewebe mittels einer 2D-Multiphasen-Tagging-Technik (1998)
    Springer
    Der Radiologe 38 (1998), S. 539-544 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Gebärmutterarterien ; Zervixkarzinom (FIGO IIB-IVA) ; 2D-Multiphasen-Tagging ; Key words Uterine arteries ; cervix ; Advanced cervical carcinoma (FIGO IIB-IVA) ; Blood-bolus-tagging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose. The aim of this pilot study was to evaluate a 2D-STAR technique as a non contrast-enhanced approach to demonstrate the uterine artery and its branches and to assess the cervical uterine blood flow in healthy volunteers and in patients with advanced uterine cervical carcinoma Materials and methods. Seven healthy volunteers (mean age, 29 years) and twentytwo patients (mean age, 52 years) with advanced cancer of the uterine cervix (FIGO IIB-IVA) were prospectively examined by 2D-STAR imaging at different inversion delay times (300 ms–1900 ms) which showed the passage of a blood bolus through normal and malignant tissue of the uterine cervix. Results. The uterine artery was well visualized with short inversion delay times of 300 ms to 500 ms. It was characterized as single or multiple helical loops before dividing into its intracervical branches. The intracervical branching was observed at inversion delay times of 500 ms–700 ms. With longer inversion delay times arterial signal enhancement disappeared and cervical tissue enhancement was noted. Enhancement of benign tissue was observed at inversion delay times of 1100 ms–1700 ms, and in malignant tissue at shorter inversion delay times of 900 ms–1300 ms. The maximum of this diffuse signal enhancement of benign tissue was seen at inversion delay times of 1500 ms (1100 ms–1700 ms), in malignant tissue at significantly (P〈0.05) shorter inversion delay times of 1100 ms (900 ms to 1300). Conclusion. Our preliminary results show that the vascular supply and blood flow of the normal uterine cervix and of advanced cervical cancer can be assessed by non contrast-enhanced 2D STAR imaging and that malignant cervical tissue is earlier and stronger perfused than normal cervical tissue.
    Notes: Zusammenfassung Ziel. In dieser Studie wurde untersucht, ob mittels einer 2D-Multiphasen-Tagging (2D-MPT)-Technik dynamische Informationen über den Blutfluß in den Gebärmutterarterien und normalem sowie malignem Gebärmuttergewebe gewonnen werden können. Material und Methoden. Sieben gesunde Probanden (Durchschnittsalter, 29 Jahre) und 22 Patienten (Durchschnittsalter, 52 Jahre) mit fortgeschrittenem Zervixkarzinom (FIGO IIB-IVA) wurden prospektiv mittels einer 2D-MPT-Sequenz untersucht. In einem Intervall von 300–1900 ms nach der Markierung eines arteriellen Bolus wurden neun 2D-MPT-Bilder akquiriert, die die Passage des Bolus durch die Gebärmutterarterien und normalem und malignem Gebärmuttergewebe zeigen. Ergebnisse. Die Gebärmutterarterien füllten sich 300–500 ms nach der Blut-Bolusmarkierung und waren durch einen korkenzieherartigen Verlauf vor ihrem Eintritt in das Gebärmuttergewebe gekennzeichnet. Die intrauterinen Gefäßaufzweigungen stellten sich nach 500–700 ms dar. Nach 900– 1300 ms bzw. 1100–1700 ms war die Perfusion von malignem und normalem Gewebe sichtbar, die großen Gebärmutterarterien waren kaum bzw. nicht mehr zu sehen. Die maximale Signalintensität in malignem Gewebe war signifikant (p〈0,05) höher und wurde signifikant (p〈0,05) früher erreicht als in benignem Gewebe. Schlußfolgerung. Mit Hilfe einer 2D-MPT-Sequenz gelingt ohne Verwendung von Kontrastmitteln eine komplette dynamische Darstellung der Gebärmutterarterien und der frühen Gewebeperfusion von normalen und malignem Gebärmuttergewebe. Darüber hinaus wird malignes Gewebe früher und stärker perfundiert als normales Gebärmuttergewebe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050389
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