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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 51 (1973), S. 354-357 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 41 (1963), S. 566-566 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 42 (1964), S. 62-63 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 4 (1964), S. 225-234 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary The research concerns the effects of the content of fat in food on the plasma cholesterol (5 resp. 35 resz. 60% of the total fat calories consisted in fats which contain mostly saturated fatty acids). It had been continued over a long period on four subjects. Using nutrition poor on fat the free and the total cholesterol in the plasma is more reduced than in normal mixed food. Nutrition rich on fats proves the plasma cholesterol in the serum as high or only transitorily higher than in normal food. The lack of a regulable increase of cholesterol after doubling the supply of nutritional fats with high content of saturated fatty acids is contradictory to a common opinion, but the result of the above research corresponds with the experience of other authors to whom the proper attention was not paid.
    Notes: Zusammenfassung In langfristigen Untersuchungen an vier Versuchspersonen wurden die Auswirkungen des Fettgehaltes der Kost — 5% bzw. 35 bzw. 60% Fettkalorien in Gestalt von Fett mit Überwiegend gesättigten Fettsäuren — auf das Plasma-Cholesterin untersucht. Bei fettarmer Ernährung liegen freies und gesamtes Cholesterin im Plasma tiefer als bei gemischter Normalkost, bei fettreicher Ernährung im Serum gleich hoch oder nur vorÜbergehend höher als bei Normalkost. Es wird dargelegt, da\ das hier festgestellte Fehlen eines regelhaften Cholesterinanstiegs nach Verdoppelung der Zufuhr von Nahrungsfetten mit hohem Gehalt an gesättigten Fettsäuren einer verbreiteten Meinung widerspricht, da\ es aber in Übereinstimmung steht mit Beobachtungen anderer Autoren, die weithin unbeachtet geblieben sind.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1440
    Keywords: Osteoporosis ; Parathyroid hormone ; Bone metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In contrast to prevention, the therapy of manifest osteoporosis remains a clinically significant problem. So far all therapeutic attempts have yielded unsatisfying results. For this reason we have tried to achieve a positive bone balance by sequential stimulation and inhibition of the osseous metabolism. The therapy consisted of six 14-day courses with 400 units (1–38)hPTH per day and, in addition, starting with the 2nd week of PTH therapy, EHDP 5 mg per kg body weight per day for a total of 2 weeks. Already the initial therapeutic course resulted in a stimulation of decreased bone metabolism which could be documented by an increase in the calcium-47 accretion rate (six patients). An increase of the alkaline phosphatase could be noted (four patients); this, however, did not correlate with the calcium accretion. A positive calcium balance could, nonetheless, only be attained in four of eight patients within this period, while neither the alkaline phosphatase nor the kinetics would allow a prediction of this effect. Changes of the balance coincided with equal changes in the net calcium absorption. The urinary calcium excretion increased temporarily during the therapeutic phase. We were not able to detect an influence on the vitamin D metabolites. Histomorphometric studies did not demonstrate an increase in bone mass in the iliac creast after six therapeutic courses. Nevertheless, progressive deformations of vertebral bodies did not occur. We conclude that already after 2 weeks this therapeutic concept can lead to a stimulation of bone metabolism.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 376 (1991), S. 238-246 
    ISSN: 1435-2451
    Keywords: Crohn's disease ; Malnutrition ; Parenteral nutrition ; Enteral nutrition ; Nutritional-care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das klinische Bild und der Krankheitsverlauf beim Morbus Crohn sind im besonderen durch generelle Ernährungsstörungen und Mangelzustände geprägt. Die Funktion der Ernährungstherapie wurde dabei lange Zeit fast ausschließlich in der Wiederherstellung der Ernährungsbilanz gesehen. Die Entwicklung und klinische Anwendung einer kontrollierten parenteralen Ernährung (TPN) und enteraler Nährstofflösungen (EN) hat diesem therapeutischen Ansatz Gewicht verliehen und zusätzlich positive Effekte für bestehende konservative wie chirurgische Behandlungsschemata gezeigt. So ist in der Behandlung des akuten Schubes der Erkrankung und im Rahmen des operativen Vorgehens heute die künstliche Ernährung ein fester Bestandteil der Therapie. Dies gilt insbesondere im Kindesalter, wo Komplikationsraten reduziert und Wachstumsstörungen effektiver behandelt werden können. Die EN hat dabei eine medrigere Komplikationsrate und ist kostengünstiger im Vergleich zur TPN. Auch die Frage nach der Bedeutung der künstlichen Ernährung als primäre Therapie ist gestellt worden. Umfangreiche Studien kommen zu unterschiedlichen Ergebnissen, die aber darauf hinweisen, daß insbesondere Patienten mit einem solitären Dünndarmbefall von diesen Behandlungsmethoden profitieren. Unklar bleibt, auf welche Weise die EN bzw. TPN die Pathophysiologie bzw. -biochemie des Krankheitsverlaufes beeinflussen. Dennoch haben Rückschlüsse auf eine mögliche Reduktion z. B. von Allergenen aus der täglichen Diät Theorien über einen möglichen Zusammenhang zwischen der Pathogenese des Morbus Crohn und der Ernährung neuen Antrieb gegeben. Untersuchungen zu Ernährungsgewohnheiten der Patienten und Therapiestudien haben aber zu keinen einheitlichen Ernährungsempfehlungen geführt. Dagegen scheint unbestritten, daß die Ernährungsberatung sich positiv auf den Krankheitsverlauf auswirkt. So ist festzustellen, daß sowohl im akuten Schub wie auch in der langfristigen Betreuung des Morbus Crohn die Ernährungstherapie heute eine wichtige Behandlungskomponente darstellt.
    Notes: Summary The clinical appearance of Crohn's disease (CD) is especially marked by nutritional deficits and insufficiencies. For a long time the goal of nutritional care was reduced to the readjustment of the nutritional status. The development and clinical use of controlled parenteral nutrition (TPN) and enteral nutritive solutions (EN) did not only emphasize this therapeutical issue, but furthermore showed positive effects on the conservative as well as on the surgical treatment concepts. Therefore today artifical nutritional support is a firm part of therapy in acute, active phases or in the contact of surgical management of CD. This is especially valid in children, where complications in general and growth failure in particular can be reduced. EN is the preferred feeding method in most of the cases, due to a lower complication rate and reduced cost when compared to TPN. The question regarding the importance of nutritional support as primary therapy has also been investigated. The results differ extensively, but point towards the conclusion that patients with solitary small bowel disease do profit from this therapeutical concept. Nevertheless it is unclear, how TPN or EN interfere in the pathophysiology or -biochemistry in this process. A question about reduction e.g. of allergic components of daily diet did stimulate new theories regarding the hypothesis of a possible causal relationship between diet and the pathogenesis of CD. Investigations on dietary habits and daily dietary therapy did not reveal an overall accepted dietary guideline. Nevertheless it seems obvious that dietary counselling has a positive effect on the disease process. It does appear, that today in the acute, active phase as well as in the long term management of Crohn's disease nutritional-care is an important therapeutical method.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 311 (1982), S. 358-359 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Conclusions From the current results no appreciable influence of triacylglycerol (up to 10 mmol/serum) and cholesterol (up to 14 mmol/l serum) on digoxin and insulin radioimmunoassays with different separation techniques could be detected. Therefore it has been concluded that hyperlipoproteinemic serum samples with lipid concentrations up to these limits did not deteriorate quality control parameters.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 62 (1950), S. 490-490 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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