ISSN:
1432-1440
Keywords:
Polyneuropathy
;
Sensation
;
Ataxia
;
Chemotherapy
;
Guillain-Barré syndrome
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary An account is given of an unusual patient with acute sensory neuropathy, leading within a few weeks to almost generalized sensory loss. Generalized sensory deficits were involved in the face, tongue, and palate. He had a drug allergy from chemotherapy during an early stage of illness. An albuminocytological dissociation of the cerebrospinal fluid was noted in a few months. A sural nerve biopsy after 2 months showed a marked reduction of fibers, and extensive invasion of phagocytes throughout the endoneurium. This patient recovered poorly with profound sensory ataxia of the limbs and tongue. A possible explanation for the clinico-pathological findings may be that acute idiopathic polyradiculoneuritis (Guillain-Barré syndrome) and toxic neuropathy exert an etiological role in the extramedullary sensory system.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01731975
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