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  • 1
    Electronic Resource
    Electronic Resource
    Sm–Nd and U–Pb dating of high-pressure granulites from the Złote and Rychleby Mts (Bohemian Massif, Poland and Czech Republic) (2005)
    Oxford, UK : Blackwell Science Inc
    Journal of metamorphic geology 23 (2005), S. 0 
    Details
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: In the Orlica-Śnieżnik complex at the NE margin of the Bohemian Massif, high-pressure granulites occur as isolated lenses within partially migmatized orthogneisses. Sm–Nd (different grain-size fractions of garnet, clinopyroxene and/or whole rock) and U–Pb [isotope dilution-thermal ionization mass spectrometry (ID-TIMS) single grain and sensitive high-resolution ion microprobe (SHRIMP)] ages for granulites, collected in the surroundings of Červený Důl (Czech Republic) and at Stary Gierałtów (Poland), constrain the temporal evolution of these rocks during the Variscan orogeny. Most of the new ages cluster at c. 350–340 Ma and are consistent with results previously reported for similar occurrences throughout the Bohemian Massif. This interval is generally interpreted to constrain the time of high-pressure metamorphism. A more complex evolution is recorded for a mafic granulite from Stary Gierałtów and concerns the unknown duration of metamorphism (single, short-lived metamorphic cycle or different episodes that are significantly separated in time?). The central grain parts of zircon from this sample yielded a large spread in apparent 206Pb/238U SHRIMP ages (c. 462–322 Ma) with a distinct cluster at c. 365 Ma. This spread is interpreted to be indicative for variable Pb-loss that affected magmatic protolith zircon during high-grade metamorphism. The initiating mechanism and the time of Pb-loss has yet to be resolved. A connection to high-pressure metamorphism at c. 350–340 Ma is a reasonable explanation, but this relationship is far from straightforward. An alternative interpretation suggests that resetting is related to a high-temperature event (not necessarily in the granulite facies and/or at high pressures) around 370–360 Ma, that has previously gone unnoticed. This study indicates that caution is warranted in interpreting U–Pb zircon data of HT rocks, because isotopic rejuvenation may lead to erroneous conclusions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1525-1314.2005.00566.x
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  • 2
    Electronic Resource
    Electronic Resource
    Cloning and sequencing of a gene coding for an actin binding protein of Saccharomyces exiguus
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression 1217 (1994), S. 214-218 
    Details
    ISSN: 0167-4781
    Keywords: (S. exiguus) ; Actin binding protein ; SH3 domain
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4781(94)90039-6
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  • 3
    Electronic Resource
    Electronic Resource
    An unspecific RNA (adenine-1-)methylase from the dinoflagellate Crypthecodinium cohnii
    Amsterdam : Elsevier
    FEBS Letters 55 (1975), S. 245-248 
    Details
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(75)81002-7
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  • 4
    Electronic Resource
    Electronic Resource
    Metall-Pseudohalogenide
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 35 (1972), S. C17-C19 
    Details
    ISSN: 0022-328X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0022-328X(00)86866-7
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  • 5
    Electronic Resource
    Electronic Resource
    Comparison of two methods for the determination of substance P immunoreactivity in human cerebrospinal fluid: Sulphopropyl-Sephadex ion-exchange chromatography and/or reversed-phase high-performance liquid chromatography combined with radioimmunoassay
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 425 (1988), S. 175-181 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-4347(88)80018-5
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  • 6
    Electronic Resource
    Electronic Resource
    Chromosomenaberrationen in Tumorasziteszellen des Ehrlich-Karzinoms der Maus nach Röntgenbestrahlungin vivo bei verschiedenen Sauerstoffpartialdrucken (1956)
    Springer
    Cellular and molecular life sciences 12 (1956), S. 21-21 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The frequency of radio-induced fragments of chromosomes increases in ascites-cells of the Ehrlich-carcinoma at higher oxygen partial pressure, to which test animals are exposed during irradiation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02156986
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  • 7
    Electronic Resource
    Electronic Resource
    Serum amyloid A – an indicator of inflammation in ankylosing spondylitis (2000)
    Springer
    Rheumatology international 19 (2000), S. 119-122 
    Details
    ISSN: 1437-160X
    Keywords: Key words Ankylosing spondylitis ; Serum amyloid A ; Disease activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Biological markers of inflammation are useful for the diagnosis and monitoring of inflammatory rheumatic diseases. The present study tested, whether serum amyloid A (SAA) could be used as a marker of inflammatory disease activity in ankylosing spondylitis (AS). In 72 patients with AS, the two valuable surrogate markers of disease activity, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), and an established clinical activity score (Bath Ankylosing Spondylitis Disease Activity Index, BASDAI) were correlated to the serum levels of SAA. It was found that SAA correlates well with ESR, CRP, and BASDAI. Because of its strong correlation, SAA seems to be an additional very useful disease activity marker. When used in diagnosis, and especially in monitoring of inflammation, further studies are required. Another interesting point of view is the described role of plasma SAA as a precursor of Amyloid A (AA) protein in secondary amyloidosis, a known complication in AS. In all probability, high circulating SAA levels are a predisposing indicator of disease activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002960050114
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  • 8
    Electronic Resource
    Electronic Resource
    Ankylosing spondylitis and infections of the female urogenital tract (1998)
    Springer
    Rheumatology international 17 (1998), S. 181-184 
    Details
    ISSN: 1437-160X
    Keywords: Key words Ankylosing spondylitis ; Genitourinary infection ; Chlamydia trachomatis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty-two female patients with confirmed ankylosing spondylitis (AS) and 33 women of similar age with pure ileitis terminalis Crohn were examined for genitourinary infection. Urethral syndrome was found in 15 out of 32 patients with AS: 11 of them had urethritis and 4 urethritis associated with vaginitis. Five women of the control group suffered from urethritis. In all cases with genitourinary infection, Chlamydia trachomatis was isolated. By comparing the AS-patients (urogenital infection group and the non-infected group) with regard to other present clinical parameters, it was found, as expected, that the erythrocyte sedimentation rate in the 1st hour was significantly higher in the infected group. In addition, the infected patients had a significantly higher incidence of enthesopathy, involvement of the spinal column, and higher C-reactive protein values (CRP ≥ 5 mg/l). A family history of AS was equally present. Other clinical parameters, such as inflammatory involvement of the joints and HLA-B27 correlation, did not differ significantly between infected and non-infected patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002960050031
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  • 9
    Electronic Resource
    Electronic Resource
    Elderly onset rheumatoid arthritis and polymyalgia rheumatica: ultrasonographic study of the glenohumeral joints (1998)
    Springer
    Rheumatology international 17 (1998), S. 229-232 
    Details
    ISSN: 1437-160X
    Keywords: Key words Polymyalgia rheumatica ; Elderly onset rheumatoid arthritis ; Ultrasonography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The glenohumeral joints of 32 patients (aged 60 or above) were examined using ultrasonography. Thirteen patients were suffering from characteristic polymyalgia rheumatica (PMR) symptoms. In contrast 19 other patients initially had similar complaints, but were diagnosed as having elderly onset rheumatoid arthritis (EORA) upon development of typical symptoms. Ultrasound examination revealed glenohumeral joint inflammation in 61% (8 out of 13) of the patients with PMR and 63.2% (12 out of 19) of the patients with EORA. These findings suggest that a subgroup of patients with PMR and EORA suffers from shoulder joint inflammation and this synovitis/bursitis/intraarticular effusion might play an important role in the understanding of their symptoms. We conclude that overlapping forms of PMR and a predominate rheumatoid factor negative subgroup of EORA might exist and should be further characterized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002960050039
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  • 10
    Electronic Resource
    Electronic Resource
    Bone metabolism and bone mineral density of systemic lupus erythematosus at the time of diagnosis (1999)
    Springer
    Rheumatology international 18 (1999), S. 137-140 
    Details
    ISSN: 1437-160X
    Keywords: Key words Systemic lupus erythematosus ; Osteoporosis ; Bone (and mineral)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Recent studies have shown that systemic lupus erythematosus (SLE) is associated with a loss of trabecular bone. However, these changes have not been not described in patients with SLE at the time of diagnosis. To investigate the markers of bone metabolism 20 female patients with a recently manifested clinical picture of SLE were selected. All patients included in this study met the ARA criteria (for classification) of SLE. For comparison, 35 female patients with SLE, which had previously manifested itself and which had been treated with glucocorticoids, were included in a second group. A control group (III) consisting of 20 healthy individuals of the same age was formed to compare the results obtained. Test parameters comprised both serum levels of osteocalcin (OC) as the marker for bone formation and crosslinks excretion (CE) in urine as a specific marker for bone resorption. The bone density (BMD) was examined by dual energy X-ray absorption (DEXA) of the vertebral column (L2–L4), femoral neck, Ward's triangle and trochanter. The patients under study received either no medication or nonsteroidal antirheumatic drugs. The BMD of the vertebral column was significantly lower than expected in SLE-afflicted subjects of group II when compared with the age-matched normal female controls. The reduction of BMD in female patients with SLE was related to the significantly increased excretion of urinary pyridinoline, to hypoparathyroidism, and to the decrease in serum OC. Bone loss in women with fresh manifestation of SLE (I) increases to a degree similar to that of patients in group II. Lowered BMD predicts an increased risk for bone fractures. Therefore, female premenopausal SLE patients should be monitored for osteoporosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002960050072
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