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  • 1
    Electronic Resource
    Electronic Resource
    Experimental evidence that polyoma-specific tumour antigen is a virus-coded protein (1975)
    [s.l.] : Nature Publishing Group
    Nature 258 (1975), S. 756-758 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] PV DNA I was used as template for the Escherichia coli DNA-dependent RNA polymerase. After transcription viral DNA was thoroughly removed by exhaustive DNase treatment (M.G. and A.G., unpublished). To prevent any contamination with viral DNA, the cRNA preparation was then centrifuged to equilibrium ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/258756a0
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  • 2
    Electronic Resource
    Electronic Resource
    Inhibition by interferon of SV40 tumor antigen formation in cells injected with SV40 cRNA transcribed in vitro
    Amsterdam : Elsevier
    FEBS Letters 39 (1974), S. 249-251 
    Details
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(74)80122-5
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  • 3
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1980)
    Springer
    Journal of molecular medicine 58 (1980), S. 541-542 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01477074
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  • 4
    Electronic Resource
    Electronic Resource
    Über Abbauprodukte des Inter-alpha-Trypsininhibitors im Serum (1977)
    Springer
    Journal of molecular medicine 55 (1977), S. 337-342 
    Details
    ISSN: 1432-1440
    Keywords: Inter-alpha-trypsin inhibitor ; Inflammation ; Nephropathy ; Inter-alpha-Trypsininhibitor ; Entzündung ; Nephropathie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der humorale Inter-alpha-Trypsin-inhibitor ist als Prekursor des säurestabilen Serum-trypsin-plasmin-inhibitors zu definieren. Dieser Inhibitor wird glomerulär filtriert, die Serumkonzentration steigt bei Nephropathien stark an. An Hand einer neuen Bestimmungsmethode für den Prekursor konnte festgestellt werden, daß bei entzündlichen Erkrankungen trotz normaler Ausscheidung des säurestabilen Abbauprodukts ein Abfall der Prekursorkonzentration einen gesteigerten Inter-alpha-trypsininhibitor Umsatz anzeigt. Die Ergebnisse belegen, daß die Niere sicher das Hauptabbauorgan für den Prekursor ist, da bei Nephropathien ein Anstieg der Prekursorkonzentration gefunden wird. Trotz eingeschränktem Abbau ist jedoch parallel dazu eine Zunahme der Inhibitorkonzentration zu beobachten. Dies ist nur zu erklären, wenn angenommen wird, daß der Abbau des Inter-alpha-trypsininhibitors im Organismus ein ubiquitärer Vorgang ist.
    Notes: Summary The humoral inter-alpha-trypsin inhibitor is to define as precursor of the acid stable trypsin-plasmin-inhibitor in the serum. The inhibitor is filtrated by the glomerulum and excreted in the urine. The serum level of the inhibitor is increased in nephropathy. Using a new assay for the intact precursor it was found that during inflammation the decreased precursor level indicates an increased turnover, though the glomerular filtration of the acid-stable inhibitor is within normal range. The increase of the precursor level during nephropathy indicates that the kidney is the main degradation organe for the inter-alpha-trypsin inhibitor. Nevertheless, an increase of the acid-stable inhibitor is to be seen. This fact is only to explain if it is assumed that the inter-alpha-trypsin inhibitor is permanently degraded everywhere in the organism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01488112
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  • 5
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1979)
    Springer
    Journal of molecular medicine 57 (1979), S. 1303-1304 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01492987
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  • 6
    Electronic Resource
    Electronic Resource
    Über Abbauprodukte des Inter-alpha-Trypsininhibitors im Serum (1977)
    Springer
    Journal of molecular medicine 55 (1977), S. 343-345 
    Details
    ISSN: 1432-1440
    Keywords: Inter-alpha-trypsin inhibitor ; Inflammation ; Nephropathy ; Inter-alpha-Trypsininhibitor ; Entzündung ; Nephropathie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei der Freisetzung des säurestabilen Serum-Trypsin-Plasmin-Inhibitors aus dem Inter-alpha-Trypsininhibitor in vivo, entstehen zusätzlich säurelabile Abbauprodukte, die immunologisch bestimmt werden können. Das Hauptabbauprodukt wird im Gegensatz zum säurestabilen Inhibitor nicht durch die Niere ausgeschieden. Dieses Produkt häuft sich im Serum bei verschiedenen Erkrankungen an. Die erhöhte Konzentration dieses Abbauprodukts gestattet auch in den Fällen einen erhöhten Umsatz nachzuweisen, bei denen die Bestimmung des intakten Inter-alpha-Trypsininhibitors oder des filtrierbaren Derivates keinen solchen Nachweis zuläßt.
    Notes: Summary Simultaneous to the liberation of the acid stable trypsin-plasmin-inhibitor from the inter-alpha-trypsininhibitor in vivo, acid labile degradation products are set free. The main product can be estimated by immunological methods. This product is not excreted by the kidney in contrast to the acid stable inhibitor. The product accumulates in serum in different diseases. An increased concentration of this product indicates also an increased turn-over of the inter-alpha-trypsin inhibitor in the case when the concentration of the intact inter-alpha-trypsin inhibitor or of the filtrable derivative are within normal range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01488113
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  • 7
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1979)
    Springer
    Journal of molecular medicine 57 (1979), S. 911-912 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01477031
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  • 8
    Electronic Resource
    Electronic Resource
    The biological activity of different forms of Polyoma Virus DNA and viral DNA fragments (1973)
    Springer
    Molecular biology reports 1 (1973), S. 233-241 
    Details
    ISSN: 1573-4978
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Mouse tissue culture cells were infected with different forms of Polyoma Virus (PV) DNA or virus DNA fragments by means of a microinjection technique and stained for PV-tumor (T) antigen and virus capsid (V) antigen 48 hr after injection. The efficiency of PV-DNA 1 (20S) to induce T- and V-antigen was within the same range as the efficiency of the full virus particle. DNA II (16S) showed a reduced capacity for both T- and V-antigen induction. Single stranded DNA molecules (16 or 18S) and double stranded DNA fragments (12S) led to T-antigen but not V-antigen synthesis. Simultaneous transfer of 16S and 18S DNA revealed T- and V-antigen formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00357647
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  • 9
    Electronic Resource
    Electronic Resource
    Endokarditis-Prophylaxe 1998 – was ist gesichert (1998)
    Springer
    Zeitschrift für Kardiologie 87 (1998), S. 663-666 
    Details
    ISSN: 1435-1285
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003920050224
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  • 10
    Electronic Resource
    Electronic Resource
    Bacterial-mycotic liver abscess in a non-immunocompromised host (1984)
    Springer
    Infection 12 (1984), S. 256-257 
    Details
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eine 70jährige, zuvor gesunde Patientin entwickelte sieben Wochen nach einem abdominal-chirurgischen Eingriff einen Leberabszeß von gemischt bakteriell-mykotischer Ätiologie. Die Diagnose wurde durch Sonographie und Aspiration gesichert. Wiederholte Drainage mit Spülbehandlung (Povidonjod) und systemischer Mezlocillin-Therapie waren erfolglos; erst Langzeitbehandlung mit Piperacillin und Miconazol inklusive Drainageentfernung waren kurativ.
    Notes: Summary We are presenting the case of a 70-year-old, formerly healthy patient. Seven weeks after abdominal surgery, a liver abscess was diagnosed by sonography and aspiration. Cultures revealed a mixed bacterial-fungal etiology. Treatment with irrigation (povidone iodine) and parenteral mezlocillin failed. Final cure was only achieved when long-term treatment with piperacillin and miconazole was initiated and abscess drainage removed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01645953
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