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  • 1
    Electronic Resource
    Electronic Resource
    Hemodialysis in metacresol poisoning (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 472-472 
    Details
    ISSN: 1432-1440
    Keywords: Hemodialysis ; Metacresol ; Poisoning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180526
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of isosorbide-5-nitrate during haemodialysis and peritoneal dialysis (1987)
    Springer
    European journal of clinical pharmacology 32 (1987), S. 503-505 
    Details
    ISSN: 1432-1041
    Keywords: isosorbide-5-nitrate ; renal failure ; haemodialysis ; peritoneal dialysis ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of isosorbide-5-nitrate (IS-5-N) was studied in ten patients on haemodialysis (HD) after a single oral dose of 20 mg IS-5-N, and in six patients on continuous ambulatory peritoneal dialysis (CAPD) after repeated oral doses of 3×20 mg IS-5-N. There was significant removal of IS-5-N from blood during HD; Cmax decreased by about 20%, AUC(0–8 h) by 30% and t1/2 by about 20% from 4.3 to 3.4 h, and plasma clearance was increased by 81 ml/min. No important loss of IS-5-N was observed in patients on CAPD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00637678
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Mexiletin bei terminaler Niereninsuffizienz und verschiedenen Dialyseverfahren (1989)
    Springer
    Journal of molecular medicine 67 (1989), S. 995-998 
    Details
    ISSN: 1432-1440
    Keywords: Mexiletine ; Renal insufficiency ; Removal by hemodialysis ; Hemofiltration ; Peritoneal dialysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We monitored the plasma levels of mexiletine in 20 dialysis patients with severe cardiac arrhythmias after repeated oral administration and the elimination by various dialysis procedures. The levels of mexiletine in plasma and dialysate were assayed by high-pressure liquid chromatography. After repeated administration of mexiletine 400–600 mg/day trough levels were in the range from 500–2,000 ng/ml. Treatment controlled by Holter monitoring was effective in 13/20 patients. Doses of 600 mg/day and more often were not tolerated by patients with dialysis after some weeks. There was no important removal of mexiletine from plasma during hemodialysis, hemofiltration, peritoneal dialysis, or plasmapheresis. In conclusion, we recommend a slightly reduced dosage of 400–600 mg mexiletine/day (usually 600–800 mg) for patients with end-stage renal insufficiency, irrespective of dialysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01716063
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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