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  • 1
    ISSN: 1434-453X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geologie und Paläontologie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Rock mechanics and rock engineering 28 (1995), S. 111-124 
    ISSN: 1434-453X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geologie und Paläontologie
    Notizen: Summary This paper presents the methodology adopted for assessing experimental parameters relevant to computer rockfall analyses and describes the data gathered from several in situ rockfall tests carried out by ISMES and ENEL CRIS during recent years. Through the calculation of block velocities during their fall from and onto slopes of various geometry, and the measurement of the run-out distances, heights of bounce and the geometric characteristics of blocks, the following experimental parameters were studied: Restitution Coefficient, Rolling Friction Coefficient, dispersion of trajectories, effect of block geometry on its fall, and efficiency of a ditch, at the bottom of a slope, for arresting fallen blocks.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Social psychiatry and psychiatric epidemiology 32 (1997), S. 428-434 
    ISSN: 1433-9285
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The aim of this observational study was to assess the rates of aggressive and violent behavior in patients admitted to an Italian emergency psychiatric unit and to explore possible risk factors for patient violence. In a population of 313 consecutive patients, we considered aggressive or violent behavior, rated according to a hierarchy from no aggressive behavior to serious physical violence. The results confirm that young age, psychotic symptoms, excitement, akathisia, and diagnosis of personality disorder are risk factors for violent behavior. The unique and major finding of the study is the low prevalence of aggressive and violent acts in this sample of patients, possibly related to their cultural background and to the system of psychiatric care. These data provide supportive evidence for the importance of sociocultural factors in the behavior of psychiatric patients and suggest the need to explore new strategies of prevention and treatment of patient aggression and violence. A non-restraint policy could be a critical factor in reducing violence among psychiatric inpatients.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Neurological sciences 17 (1996), S. 409-418 
    ISSN: 1590-3478
    Schlagwort(e): Prevalence ; Risk factors ; Tardive dyskinesia ; Tardive dystonia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Al fine di replicare i risultati di un nostro precedente studio sulla distonia tardiva (TDt) e di allargare il campione dei pazienti studiati, abbiamo esaminato 154 pazienti psichiatrici ricoverati, con una storia di esposizione cumulativa ai neurolettici di almeno 3 mesi. Lo studio fornisce ulteriori dati che giustificano la distinzione tra discinesia tardiva (TDk) e TDt. Rispetto ai pazienti affetti da TDk i pazienti con TDt tendono ad essere più giovani, di sesso maschile, con una minor durata di esposizione ai neurolettici e con un disturbo del movimento di grado più severo. La TDt risulta essere la forma più frequente di distonia tardiva. Ci sono dati che indicano che la sua prevalenza sia stata, fino a questo momento, sottovalutata.
    Notizen: Abstract In order to replicate the results of our previous study of tardive dystonia (TDt) and to enlarge the studied sample, we examined 154 consecutive psychiatric in-patients who had been exposed to neuroleptic drugs for a cumulative period of at least three months. The present study provides further data supporting a distinction between TDt and tardive dyskinesia (TDk). The patients with TDt tend to be younger, male, less exposed to neuroleptic drugs, and to have a more severe movement disorder. TDt appears to be the most frequent form of secondary dystonia, and there is evidence that its prevalence has so far been underestimated.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Bioprocess engineering 21 (1999), S. 553-560 
    ISSN: 0178-515X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Abstract Aprotinin is a protease inhibitor found in bovine organs and used as a valuable human therapeutic compound. In this work, a process for the recovery of aprotinin from insulin industrial process effluent via affinity adsorption on immobilized trypsin and chymotrypsin was developed. First, process conditions were set as a result of a study of the effects of pH and ionic strength on pure aprotinin adsorption and desorption utilizing an experimental design methodology. The best conditions obtained with immobilized trypsin as the ligand were adsorption at 0.018 M NaCl and pH 8.7 and desorption at 0.018 M NaCl and pH 2.1. For immobilized chymotrypsin, the best conditions were adsorption at 0.582 M NaCl and pH 8.0 and desorption at 0.582 M NaCl and pH 2.1. Recovery of the inhibitor from the effluent was carried out utilizing a two-step process: trypsin-agarose adsorption followed by chymotrypsin-agarose adsorption. Analysis of the chromatographic fractions by trypsin and chymotrypsin inhibition and capillary electrophoresis assays strongly suggested that the recovered inhibitor is aprotinin.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Euphytica 37 (1988), S. 121-127 
    ISSN: 1573-5060
    Schlagwort(e): Lycopersicon esculentum ; processing tomato ; heritability ; pH ; colour ; soluble solids ; choice of parents
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Summary The genetic basis of pH, colour and soluble solids in processing tomato is examined. In a first experiment, aimed at identifying the base populations with which to start selection, parents, F1 and F2 progenies of an 8 × 8 diallel cross without reciprocals were tested. The results indicate that additive, dominance and additive x additive epistatic effects were noticeable for the three characters. Higher order interlocus interactions were also detected. As to the soluble solids, a trait for which higher order epistatic effects were less marked, the breeding potential of the cross combinations was assessed by calculating the expected mean values at the F∞ generation. Some cross populations having ‘C33’ or ‘C35’ as parent appeared to be superior. A second experiment was conducted to collect data on the heritability of the foregoing qualitative traits by utilizing the regressions of F3 offspring on F2 parents. The low heritability coefficients observed would suggest the ineffectiveness of individual selection in early generations. In both the F2 and F3 generations rather low correlation coefficients among the three quality traits were observed.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    ISSN: 1590-3478
    Schlagwort(e): Depression ; Stroke ; Rating Scale ; Post-Stroke Depression
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Gli autori descrivono una nuova scala, denominata Post-Stroke Depression Rating Scale (PSDRS) costruita specificamente per la valutazione della depressione e della sintomatologia ad essa correlata nei pazienti colpini da stroke. Essi presentano alcuni dati sull'attendibilità e validità diagnostica della PSDRS e riportano i primi risultati ottenuti somministrando la nuova scala a 68 pazienti colpiti da stroke e a 10 pazienti affetti da depressione endogena. Il confronto fra i risultati ottenuti alla PSDRS dai pazienti classificati come “Depressione Maggiore” conseguente a stroke o di natura funzionale sembra indicare che le due forme di depressione sono soltanto in parte sovrapponibili. Nei pazienti classificati come depressione maggiore post-stroke, parte della sintomatologia sembra duvuta o all'effetto diretto della lesione o alla reazione psicologica nei confronti della disabilità e degli handicaps provocati dalla lesione stessa.
    Notizen: Abstract The authors describe a new scale, the Post-Stroke Depression Rating Scale (PSDRS), specifically constructed to investigate the emotional, affective and vegetative disorders of stroke patients. They also report some preliminary data concerning the validity and reliability of the new scale and of its sections and the first results obtained administering the PSDRS to 68 stroke patients and 10 subjects affected by a “functional” form of major depression. The comparison between the results obtained on the PSDRS by patients classified (on the basis of DSM III diagnostic criteria) as having major depression of either vascular or functional origin seems to show an incomplete overlap between these two forms of depression. In patients classified as having major post-stroke depression, part of the symptomatology seems to be due either to the direct effect of the brain lesion or to the psychological reaction of the patient to the disabilities and handicaps provoked by the lesion.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Neurological sciences 12 (1991), S. 157-161 
    ISSN: 1590-3478
    Schlagwort(e): Progressive supranuclear Palsy ; methysergide ; therapy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Presentiamo uno studio clinico di un uomo di 69 anni con una storia clinica di notevole difficoltà nella deambulazione e di riduzione dei movimenti coniugati volontari oculari in lateralità e assenza di essi in verticalità. Questa sintomatologia ha portato alla diagnosi di morbo di Parkinson ed è stato iniziato un trattamento con L-DOPA e anticolinergici. Poi il trattamento è stato sospeso e non si è assistito a varianti della condizione clinica. È stato allora iniziato un trattamento con methysergide e la risposta alla cura è stata monitorizzata registrandola con videocssetta. Sulla base della nostra esperienza e dei dati riportati in letteratura rieniamo che il methysergide è in grado di ottenere miglioramenti nella sintomatologia della paralisi sopranucleare progressiva.
    Notizen: Abstract We present a clinical study of a patient aged 69 years with a clinical history of severe difficulty in walking and voluntary conjugate eye movement reduction in sideways glance and absence in vertical gaze. These symptoms led to diagnosis of Parkison disease and treatment with L-Dopa+anticholinergics drugs. The treatment with antiparkinsonian drugs was suspended and no change in his clinical condition resulted. Methysergide therapy was initiated and the patient's response was monitored by video recording. On the basis of our experience and the data reported in the literature we believe that methysergide therapy affords some relief of symptoms in patients suffering from PSP.
    Materialart: Digitale Medien
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