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  • 1
    Electronic Resource
    Electronic Resource
    Aldosteron, Cortisol und Plasma-Renin-Aktivität beim Phäochromocytom (1974)
    Springer
    Journal of molecular medicine 52 (1974), S. 719-721 
    Details
    ISSN: 1432-1440
    Keywords: Aldosterone ; renin ; pheochromocytoma ; Aldosteron ; Renin ; Phaechromocytom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Sieben von 8 Patienten mit einem Phäochromocytom zeigten eine über die Norm erhöhte Plasma-Renin-Aktivität (〉3 ng/ml/3 h). Bei 4 der 7 Patienten mit Hyperreninismus konnte gleichzeitig auch ein abnorm hohes Plasma-Aldosteron nachgewiesen werden (〉120 pg/ml). Seitengetrennte Bestimmungen der Plasma-Renin-Aktivität im Nierenvenenblut zweier Patienten zeigten, daß als Ursachen des Hyperreninismus sowohl eine Verringerung der Nierendurchblutung durch Tumorkompression im Sinne eines Goldblattmechanismus als auch eine Stimulation der renalen Reninsekretion durch Katecholamine in Frage kommen können. Bei 2 unserer Patienten mit einem Phäochromocytom fand sich eine über die Norm gesteigerte Cortisolsekretion.
    Notes: Summary Seven of eight patients with pheochromocytoma showed elevated plasma renin activity (〉3 ng/ml/3 hr). Four of these seven patients simultaneously had abnormally high plasma aldosterone (〉120 pg/ml). It was found by selective determinations of plasma renin activity in both renal veins that two different mechanisms may be responsible for the observed hyperreninism. Firstly, the pheochromocytoma can lead mechanically to a reduction in renal blood flow inducing an increased renin secretion. Secondly, catecholamines are known to stimulate renin secretion. Two of the eight patients with pheochromocytoma showed an increased cortisol secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01469334
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  • 2
    Electronic Resource
    Electronic Resource
    Bichromatic two-photon photoemission spectroscopy of image potential states on Ag(100) (1990)
    Springer
    Applied physics 51 (1990), S. 322-326 
    Details
    ISSN: 1432-0630
    Keywords: 73.20At ; 79.60Cn ; 79.20Ds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Bichromatic two-photon photoemission spectroscopy (Bi2PPES) leads to an increased signal-to-noise ratio compared to conventional two-photon photoemission spectroscopy and therefore allows the observation of the first four image potential states as well as a lineshape analysis with improved accuracy on Ag(100). The n=2 image state with a measured linewidth of 37 meV FWHM is the narrowest unoccupied structure measured on any solid surface so far. The intrinsic linewidths of the first two image states were determined as 21±4 meV and 5±5 meV, respectively, in reasonable agreement with theoretical calculations. Disordered adsorption of oxygen on Ag(100) leads to a linewidth broadening of the first and — to a lesser extent — of the second image potential state. A quantitative analysis of the broadening suggests that the underlying mechanism is lifetime shortening due to scattering of the image state electrons by the adsorbate atoms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00324312
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  • 3
    Electronic Resource
    Electronic Resource
    Glial Cell Line-derived Neurotrophic Factor: the Lateral Cerebral Ventricle as a Site of Administration for Stimulation of the Substantia Nigra Dopamine System in Rats (1996)
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 8 (1996), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The direct application of recombinant human glial cell line-derived neurotrophic factor (rhGDNF) to the deep structures of the nigrostriatum has been shown previously to augment dopamine function and inhibit loss of substantia nigra neurons in rodent models of Parkinson's disease. The present studies were designed to determine whether administration of rhGDNF into the lateral ventricle, a more clinically accessible intracranial target, is capable of augmenting dopamine function of the nigrostriatal pathway in normal rats. Single bolus intracerebroventricular (i.c.v.) injections of rhGDNF increased locomotor activity and decreased food and water consumption and body weight gain in a dose-dependent manner. rhGDNF increased concentrations of dopamine and dopamine metabolites in the substantia nigra, ventral tegmental area and hypothalamus, but had no significant effects in the striatum. rhGDNF had no effect on striatal or substantia nigral serotonin (5-HT) and 5-hydroxyindoleacetic acid levels, but these levels were significantly increased in the ventral tegmental area and hypothalamus respectively. The augmentation of the dopamine and 5-HT systems was detected 2 weeks but not 3 days or 6 weeks after rhGDNF administration. After a repeat injection of i.c.v. rhGDNF (6 weeks after the initial injection), substantia nigral dopamine, 5-HIAA and noradrenalin levels were increased. These results indicate that i.c.v. administration of rhGDNF has an influence on adult rat dopamine neurons. This route of administration may be useful for stimulating dopamine neurons in Parkinson's disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.1996.tb01293.x
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  • 4
    Electronic Resource
    Electronic Resource
    Comparative analysis of photosensitivity in photosystem I donor and acceptor side mutants of Chlamydomonas reinhardtii (2003)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 26 (2003), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Electron input from plastocyanin into photosystem I (PSI) is slowed down in the Chlamydomonas reinhardtii mutants affected at the donor side (PsaF or PsaB, lumenal loop j) of PSI. In contrast, electron exit from PSI to ferredoxin is diminished in the PSI acceptor side PsaC mutants K35E and FB1. Although, the electron transfer reactions are diminished to a similar extent in both type of mutants, the PsaC mutants K35E and FB1 are more light-sensitive than the PsaF-deficient strain 3bF or the PsaB mutants E613N and W627F. To assess the differential photosensitivity of donor and acceptor side mutants fluorescence transients, gross oxygen evolution and uptake, PSII photo-inhibition and rate of recovery were measured as well as NADP+ photoreduction. The NADP+ photoreduction measurements indicated that the donor side is limiting the reduction rate. In contrast, measurements of gross oxygen evolution and uptake showed that the reducing side limits linear electron transfer. However, under high light, donor and acceptor side mutations lead to PSII photo-inhibition and to a diminished rate of PSII recovery, cause lipid peroxidation and result in a decrease in the levels of PSI and PSII. The wild type is not affected under the same conditions. These responses are most pronounced in the PsaC-K35E and PsaB-W627F mutants, and they correlate with the light sensitivity of these strains. The correlation between limitation of electron transfer through PSI and the formation of reactive oxygen species as a cause for the light-sensitivity is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2003.01105.x
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  • 5
    Electronic Resource
    Electronic Resource
    Polarization spectra of free base tetraphenylporphyrin and its Zn-, Cu-metallo complexes
    Amsterdam : Elsevier
    Journal of Molecular Structure 56 (1979), S. 95-105 
    Details
    ISSN: 0022-2860
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-2860(79)80141-6
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  • 6
    Electronic Resource
    Electronic Resource
    The major histocompatibility complex and human evolution
    Amsterdam : Elsevier
    Trends in Genetics 6 (1990), S. 7-11 
    Details
    ISSN: 0168-9525
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0168-9525(90)90042-5
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  • 7
    Electronic Resource
    Electronic Resource
    Applications of high-speed counter-current chromatography for the separation and isolation of natural products
    Amsterdam : Elsevier
    Journal of Chromatography A 538 (1991), S. 193-202 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(01)91637-1
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  • 8
    Electronic Resource
    Electronic Resource
    Germacra-12,6β-olides from Montanoa revealii and M. mollissima
    Amsterdam : Elsevier
    Phytochemistry 23 (1984), S. 1063-1066 
    Details
    ISSN: 0031-9422
    Keywords: Asteraceae ; Heliantheae ; Montanoa mollissima ; Montanoa revealii ; germacranolides. ; sesquiterpene lactones
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)82609-6
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  • 9
    Electronic Resource
    Electronic Resource
    Melampolides from Lecocarpus pinnatifidus
    Amsterdam : Elsevier
    Phytochemistry 31 (1992), S. 2747-2754 
    Details
    ISSN: 0031-9422
    Keywords: Asteraceae ; Heliantheae ; Lecocarpus pinnatifidus ; Melampodiinae ; flavonol ; melampolides ; penduletin. ; sesquiterpene lactones
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(92)83624-8
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  • 10
    Electronic Resource
    Electronic Resource
    Guaianolides and chromenes from Calea species
    Amsterdam : Elsevier
    Phytochemistry 24 (1985), S. 795-799 
    Details
    ISSN: 0031-9422
    Keywords: 2,2-dimethylchromenes ; Asteraceae ; C. prunifolia ; C. solidaginea ; Calea berteriana ; Heliantheae ; guaianolides ; heliangolides ; sesquiterpene lactones
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)84897-9
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