Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
British journal of dermatology
134 (1996), S. 0
ISSN:
1365-2133
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Summary Cutaneous lesions of Rosai-Dorfman disease (RDD) are usually associated with nodal or other extranodal localization. We describe a female patient with RDD clinically limited to the skin. The patient presented with asymptomatic red brown papules and nodules on the legs, arms, Back and nose. Histologically the lesions consisted of a proliferation of large histiocytes occasionally showing emperipolesis. Histiocytes were also observed within dilated lymphatic vessels. Immunohistochemical study showed that histiocytes expressed S-l protein and both macrophage and tonicity markers. All lesions resolved completely with Roentgen therapy. No recurrence has been observed over a 3-year follow-up period.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1046/j.1365-2133.1996.89803.x
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