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  • 1
    ISSN: 1432-1440
    Keywords: Renal artery aneurysm ; Renal cyst ; Hydronephrosis ; Coarctation of the aorta ; Radiation nephritis ; Hypertension ; Renin angiotensin system ; Nierenarterienaneurysma ; Nierencyste ; Hydronephrose ; Coarctatio aortae ; Strahlennephritis ; Hypertonie ; Renin-Angiotensin-System
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In der vorliegenden Studie wurden 19 Patienten mit seltenen Formen renaler Hypertonie untersucht: 6 Patienten mit Nierenarterienaneurysma, 6 Fälle mit unilateraler Hydronephrose, 4 Patienten mit unilateraler Nierencyste, 2 Fälle mit Coarctatio aortae und assozierter Nierenarterienstenose und ein Patient mit Strahlennephritis. Die Plasma-Renin-Aktivität (PRA) im Nierenvenenblut wurde bei 17 der 19 Fälle bestimmt. 7 dieser 17 (41%) Patienten zeigten einen signifikanten Seitenunterschied (PRA betroffene/PRA nicht betroffene Seite) ≧1,5. Der Prozentsatz positiver Tests war in verschiedenen Kollektiven vergleichbar hoch. Nur Patienten mit unilateraler Nierencyste zeigten in keinem Fall einen signifikanten PRA-Quotienten. Eine superselektive Nierenvenenrenin-Bestimmung bei 2 Patienten mit Nierenarterienaneurysma der oberen Segmentarterie zeigte in beiden Fällen eine erhöhte Plasma-Renin-Aktivität im Bereiche des Oberpols. 15 der 19 Patienten (79%) wurden operiert. Dabei kamen entweder plastisch rekonstruktive Verfahren oder eine Nephrektomie zur Anwendung. 4 Fälle mit Nierenarterienaneurysma wurden antihypertensiv behandelt. Patienten mit unilateraler Hydronephrose zeigten postoperativ die besten Ergebnisse (3 geheilt, 3 gebessert), während bei keinem der 4 Patienten mit unilateraler Nierencyste die Blutdruckwerte durch den operativen Eingriff normalisiert werden konnten (3 gebessert, 1 nicht gebessert). Die Patienten mit Coarctatio aortae und assozierter Nierenarterienstenose sowie die 2 operierten Fälle mit Nierenarterienaneurysma zeigten alle ein gutes Ansprechen auf den gefäßrekonstruktiven Eingriff (2 geheilt, 2 gebessert). Der Patient mit Strahlennephritis schließlich war 2 Jahre nach Nephrektomie gebessert. Im Gesamtkollektiv unserer operierten Patienten war die prognostische Aussagekraft der Nierenvenenreninbestimmung beschränkt. Allerdings erwies sich die selektive Nierenvenenreninbestimmung bei Patienten mit einem Aneurysma einer Nierensegmentarterie als nützlich zur Entdeckung lokaler Reninüberproduktion.
    Notes: Summary In the present study 19 patients with rare forms of renal hypertension were investigated: 6 patients with renal artery aneurysm, 6 cases with unilateral hydronephrosis, 4 patients with unilateral simple renal cyst, 2 cases with coarctation of the abdominal aorta and associated renal artery stenosis and 1 patient with radiation nephritis. Renal venous renin activity (PRA) was determined in 17 of the 19 cases. Seven of these 17 (41%) patients showed significant PRA-ratios (PRA affected/PRA unaffected side ≧1.5). The percentage of positive tests was comparably high in the various subgroups except in patients with renal cyst, none of them showing lateralisation of renin secretion. Selective sampling in 2 patients with renal artery branch aneurysm revealed in both cases marked local renin oversecretion. Fifteen of the 19 patients (79%) were operated either by reconstruction surgery or nephrectomy. Four cases with a renal artery aneurysm were treated with antihypertensive drugs. Patients with unilateral hydronephrosis showed the best response to surgery in terms of cure rate (3 cured, 3 improved), whereas blood pressure normalisation could not be achieved in patients with simple renal cyst (2 improved, 1 unimproved). Patients with coarctation of the abdominal aorta and associated renal artery stenosis and the 2 operated cases with renal artery aneurysm showed a good effect of corrective surgery (2 cured, 2 improved). The patient with radiation nephritis finally was improved 2 years after nephrectomy. For the total group the prognostic validity of renal venous renin determination was limited. However, selective blood sampling from peripheral renal veins may be useful in cases with renal artery branch aneurysm to detect local oversecretion of renin.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    World journal of urology 4 (1986), S. 237-249 
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The vasculogenic erectile impotence is essentially more often than it has been accepted up to this day. So far, the diagnosis is established with selective arteriography of the penis. The vasculogenic impotence is more found by peripheral vasculopathies like diabetes mellitus and nicotine abuse. The diabetical diseases lead firstly to vasculopathies and secondly to neuropathies. The operative correcture of the vasculogenic impotence haas not succeeded reliable until now because the postoperative thrombotic closures of the anastomosis have showed failures. We have improved considerably the success rate with our new concept that an arterio-venous shunt is to installe addicionally near to the arterio-arterial anastomosis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 6 (1978), S. 113-118 
    ISSN: 1434-0879
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary - Urinary continence is maintained by the smooth-muscled system of the “internal sphincter”. - The striated external sphincter is not primarily responsible for continence. - One of the chief functions of the external sphincter is the initiation of voluntary micturition. Its other functions are: random interruption of the urinary stream, reflex control during an increase in intra-abdominal pressure (such as coughing, sneezing, laughing, lifting) complete emptying of the urethra after micturition and stabilization of the posterior urethra in the urogenital diaphragm. - After prostatectomy an intact external sphincter is important in order to support the smooth-muscled system which continues to be primarily responsible for continence to function as efficiently as possible. - In approximately 90% of all postprostatectomy incontinences the external sphincter is intact and this cames a good prognosis following our correcture surgery without the need for prostheses. - Only in rare post-prostatectomy incontinence cases (approx. 10%) is the external sphincter also injured. Incontinence surgery according to our method has not been satisfactory in these cases.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 16 (1988), S. 161-166 
    ISSN: 1434-0879
    Keywords: ESWL ; Renal damage ; Animal experiment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Extracorporal shock wave lithotripsy has rapidly become established world wide as a routine method for treatment of nephro-and ureterolithiasis. Although initial studies showed no tissue damaging effect by the shock waves, we found in an animal experiment using canine kidneys, the ESWL induced damage to the renal parenchyma is more marked than originally assumed. The damage is limited to the area that was focused on, and heals relatively rapidly by connective tissue encapsulation with final cicatrisation without any further residual effects being observed until now. This parenchymal damage is probably also the cause of the macrohaematuria that is always observed during therapy. The resulting tissue damage is not extensive enough to cause demonstrable reduction of function as measured by the usual methods (serum creatinine, creatinine clearance, isotopy renography, i/v-urography). The main clinical complication is the large subcapsular haematoma which, according to present knowledge, could well result from a lesion of the larger peripheral vessels. Damage to other organs such as subserous colonic and small bowel haematomata are to be expected although they do not lead to clinical symptoms.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-0879
    Keywords: Prostate ; Benign prostatic hyperplasia ; Lasers ; Laser surgery ; Histomorphology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of our study was to determine optimal treatment parameters and appropriate methods of examination for neodymium:yttrium-aluminum-garnet (Nd:YAG) high-power laser coagulation of the human prostate in relation to power setting and time. Transurethral free-beam laser coagulation was performed with the Side-Focus side-firing laser fiber in ten patients prior to planned radical surgery, of whom six underwent transperitoneal laparoscopic lymphadenectomy and laser coagulation 4–9 days prior to open surgery. Depth and volume of coagulated prostatic tissue were measured at power setting/time combinations of 40 W/90 s and 60 W/60 s, respectively, while holding total energy delivery constant. Microscopic examination in the early phase showed that epithelial cells had become loose from the basal-cell membrane. By 4–9 days there was evidence of conspicuous squamous epithelial metaplasia with a high proliferation rate as a sign of reepithelialization. Using the Side Focus side-firing laser fiber, both treatment modalities showed comparable volume coagulation. In contrast there was a significant difference between those prostates removed at 4–9 days and those removed at 60–210 min after laser coagulation. We conclude that laser-induced changes in the human prostate are conclusively discernible only after 4 days.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 5 (1977), S. 113-116 
    ISSN: 1434-0879
    Keywords: Urethral pressure profile ; Bladder pressure ; Experimental model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to improve the accuracy of bladder and urethral pressure recording, a measurement system has been tested experimentally. It is possible to measure absolute pressure values during withdrawal of the catheter only when the system is constantly perfused. The optimum relationship between catheter diameter, perfusion rate, withdrawal rate, measurement inertia and systemic resistance has been analysed.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 18 (1990), S. S57 
    ISSN: 1434-0879
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1434-0879
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1433-0563
    Keywords: Key words Angiosarcoma • Kidney • Histology • Chemotherapy ; Schlüsselwörter Angiosarkom • Nierentumor • Histologie • Chemotherapie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das primäre renale Angiosarkom ist ein äußerst seltener hochmaligner Nierentumor. Die histologische Diagnosestellung kann einige Schwierigkeiten bereiten. Wegen der ausgeprägten Tendenz zur hämatogenen Metastasierung und der schlechten Prognose sollte der chirurgischen Entfernung die gut verträgliche systemische Chemotherapie mit Doxorubicin und Ifosfamid angeschlossen werden.
    Notes: Summary The primary renal angiosarcoma is a rarely seen highly malignant tumor. Making a diagnosis based on histology may prove difficult. Because of hematogenous formation of metastases and bad prognosis in most cases we recommend that the surgical intervention be followed by the well tolerated systemic chemotherapy with Doxorubicin and Ifosfamid.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1433-0563
    Keywords: Schlüsselwörter Erektile Dysfunktion ; Abklärung ; Duplexsonographie ; Key words Erectile dysfunction ; Evaluation ; Color duplex sonography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Erectile dysfunction has taken on increasing importance in urologic practice. Still open is the question of which tests are mandatory for adequate clinical assessment of erectile dysfunction. One accepted standard modality is the intracavernous pharmacotest with vasoactive agents. In contrast, color duplex sonography is not considered mandatory although it reveals detailed information about penile vessels and functional implications. The question remains whether the information gained by color duplex sonography is relevant for therapy, making it an indispensable standard procedure. Patients with erectile dysfunction were evaluated, without preselection, by extensive history, clinical evaluation, laboratory tests, tumescence and rigidity measurements, intracavernous administration of vasoactive drugs and color duplex sonography. Seventy-nine patients were available for final analysis. Color duplex sonography revealed 39 normal tests, 16 arterial impairments, 19 venous leakages and 5 arteriovenous fistulae. Intracavernous vasoactive agents (pharmacotest) revealed 44 reactions sufficient for intercourse and 35 insufficient responses. In 89 % of patients, the diagnoses on color duplex sonography and intracavernous pharmacotesting were similar. The accuracy of the two methods in diagnosing erectile dysfunction was not statistically different (McNemar's test). In contrast to intracavernous pharmaco-testing, color duplex sonography permitted further etiologic subdivision into arterial disease, venous leakage, arteriovenous fistula and normal result. This was made possible by measuring significantly (P 〈 0.01) different arterial peak flow velocities, end-diastolic velocities and calculated resistance index. These data did not imply direct clinical consequences. Color duplex sonography and intracavernous pharmacotesting reveal comparable results concerning the diagnosis of an erectile dysfunction. In contrast to pharmacotesting, color duplex sonography reveals details of the nature of the erectile dysfunction. Because this information has no profound implications for the choice of therapeutic procedure, color duplex sonography can not be recommended as a standard procedure in the evaluation of erectile dysfunction.
    Notes: Zusammenfassung In der Abklärung einer Erektionsstörung ist der Schwellkörperinjektionstest (SKIT) als Standard unbestritten. Im Gegensatz dazu steht die farbkodierte Duplexsonographie, die zwar aussagekräftiger aber deutlich aufwendiger ist. Nur ausreichend therapierelevante Erkenntnisse würden sie zum unumgänglichen Abklärungsschritt erheben. Unsere Patienten wurden mit Anamnese, klinischer Untersuchung, Labor, Rigidometrie, SKIT sowie farbcodierter Duplexsonographie untersucht. Die intracavernöse pharmainduzierte Stimulation erfolgte stets mit 10 μg Prostaglandin E1. 79 Patienten wurden ausgewertet und analog der duplexsonographischen Diagnose gruppiert. 39 Untersuchungen ergaben einen Normalbefund, 16 eine arterielle Insuffizienz, 19 eine venöse Leakage und 5 eine arteriovenöse Fistel. Mit dem SKIT wurden 44 geschlechtsverkehrtaugliche und 35 ungenügende Reaktionen festgestellt. Hinsichtlich der Diagnose einer ED wiesen SKIT und Duplexsonographie keine relevanten Unterschiede auf. Sie zeigten eine Übereinstimmung in 89 %. Bei 19 Patienten ließ sich keine Übereinstimmung feststellen (p = ns). Mit der Duplexsonographie ließen sich signifikante (p 〈 0.01) hämodynamische Unterschiede messen. Direkte therapeutische Konsequenzen ergaben sich aus diesen Meßergebnissen keine. Duplexsonographie und SKIT liefern vergleichbare Aussagen über das Vorliegen einer erektilen Dysfunktion. Im Unterschied zum SKIT liefert die Duplexsonographie Information über die Art der ED. Da aber das therapeutische Vorgehen mit dieser Zusatzinformation nicht grundlegend beeinflußt wird, kann die Duplexsonographie nicht als Standardabklärung empfohlen werden.
    Type of Medium: Electronic Resource
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