Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Sequentiell alternierende Chemotherapie nicht-seminomatöser Hodentumoren mit Velbe/Bleomycin und Adriamycin/Cisplatin (1980)
    Springer
    Journal of molecular medicine 58 (1980), S. 823-828 
    Details
    ISSN: 1432-1440
    Keywords: Testicular neoplasms ; Stage II ; Combination chemotherapy ; Radiotherapy ; Lymph node dissection ; Testikuläre Tumoren ; Stadium II ; Kombinierte Chemotherapie ; Radiotherapie ; Lymphknoten-Exstirpation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1975 wurden 140 Patienten mit retroperitoneal-metastasierten nicht-seminomatösen Hodentumoren nach Orchiektomie und retroperitonealer Lymphadenektomie sequentiell alternierend mit den Zytostatika-Kombinationen Velbe/Bleomycin und Adriamycin/Cisplatin plus/minus Radiotherapie behandelt. Davon erhielten 68 Patienten nach totaler retroperitonealer Lymphadenektomie mit postoperativ normalisierten Tumormarkern (Stadium IIA) 6 Chemotherapie-Kurse, woran sich bei 35 Patienten eine Strahlentherapie anschloß. Vierzig Patienten wurden nach subtotaler retroperitonealer Lymphadenektomie oder bei postoperativ erhöhten Tumormarkern (Stadium IIB) und 32 Patienten nach palliativer Lymphadenektomie (Stadium IIC) mit mindestens 12 Chemotherapie-Kursen und fakultativer intermittierender Radiotherapie und/oder Relaparotomie behandelt. Der Vergleich der Behandlungsergebnisse bei den Stadien IIA und IIB ergab unabhängig von der zusätzlichen Radiotherapie nach der „Life-table“-Methode Vier-Jahres-Überlebensraten zwischen 80 und 100%. Diese günstigen Resultate sind mit den Ergebnissen bei 34 nicht adjuvant behandelten Patienten ohne histologisch nachweisbare retroperitoneale Metastasierung (Stadium I) vergleichbar. Ausdruck einer statistisch signifikant schlechteren Prognose bei fortgeschrittener retroperitonealer Metastasierung ist eine Vier-Jahres-Überlebensrate von 12% bei den Patienten im Stadium IIC.
    Notes: Summary Following orchiectomy and retroperitoneal lymph node dissection (RND) 140 patients with stage II non-seminomatous testicular cancer were treated by sequential combination chemotherapy consisting of vinblastine/bleomycin and adriamycin/cis-dichlorodiammineplatinum(II) (DDP), plus/minus radiotherapy. 68 stage IIA-patients (complete RND and normal tumor-markers thereafter) received 6 courses of chemotherapy, followed by radiotherapy in 35 patients. 40 stage IIB-patients (minor residual disease after RND or elevated tumor-markers after RND) and 32 stage IIC-patients (advanced residual disease after RND) were treated by at least 12 chemotherapy courses and optional intermittent radiotherapy and/or relaparotomy. In stage IIA and IIB disease the actuarial 4-year survival rates were between 80 and 100%. These favourable results were not significantly influenced by additional radiotherapy and corresponded to the survival rates for 34 stage I-patients. For stage IIC-patients the prognosis was significantly worse with a 12% 4-year survival rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01491102
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Malignant progression of angioimmunoblastic lymphadenopathy (1979)
    Springer
    Journal of cancer research and clinical oncology 93 (1979), S. 255-263 
    Details
    ISSN: 1432-1335
    Keywords: Angio immunoblastic lymphadenopathy ; Chromosomal abnormalitis ; Non Hodgkins lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a 79-year-old woman, the progression of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) to malignant lymphoma was observed within one year after diagnosis. Three biopsy specimens from lymph nodes and one tonsil, obtained at intervals of several months, showed an increasing destruction of the tissue architecture and the development of histological criteria for a lymphoid neoplasm, which at autopsy was confirmed as a malignant non-Hodgkin's lymphoma. The demonstration of a chromosomally abnormal clone in lymph node derived and the laboratory findings were in agreement with the histological changes and the sequential clinical deterioation. Initially, a symptom-free interval of eight months was achieved with prednisone therapy. However, this treatment failed after the malignant transformation had become evident.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00964581
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Behandlung von Non-Hodgkin-Lymphomen niedriger Malignität mit Ganzkörperbestrahlung und kombinierter Chemotherapie (1979)
    Springer
    Annals of hematology 38 (1979), S. 181-183 
    Details
    ISSN: 1432-0584
    Keywords: Low-grade malignant non-Hodgkin's lymphoma ; Multidrug therapy ; Total body irradiation ; Clinical results
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Between January, 1977, and September, 1978, 14 stage III and 7 stage IV patients with previously untreated non-Hodgkin's lymphoma were selected for low-dose fractionated total body irradiation (TBI), 150 rad in 10 fractions over 5 weeks, combined with cyclophosphamide, vincristine, and prednisone (COP) cytostatic therapy. A randomized trial was established to compare the treatment related toxicity of TBI plus COP (group A) or COP plus TBI (group B), and the efficacy to increase the response rate, particularly the complete remission rate. Fifteen patients were treated with TBI plus COP and 6 patients received COP plus TBI. The latter part of each treatment modality was delayed 6 weeks to allow recovery from the myelosuppressive effects of the foregoing one. Complete remission was achieved in 8/15 group A patients and in 3/6 treated according the group B schedule. There were no acute symptoms during either course nor could mortality associated with the treatment be observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01007964
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Portable gas chromatograph (1979)
    Springer
    Plant and soil 52 (1979), S. 595-598 
    Details
    ISSN: 1573-5036
    Keywords: Chromatograph ; Ethylene ; Hydrogen ; Methane ; Nitrogenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary An improved inexpensive portable gas chromatograph for the acetylene reduction assay of nitrogenase is described. The instrument is more convenient to use than a previously described model. Modifications permit the detection of hydrogen or methane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02277957
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...