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  • 1
    Electronic Resource
    Electronic Resource
    Scanning electron microscopy of the subarachnoid macrophages after subarachnoid haemorrhage, and their possible role in the formation of subarachnoid fibrosis (1979)
    Springer
    Acta neurochirurgica 50 (1979), S. 273-280 
    Details
    ISSN: 0942-0940
    Keywords: Macrophage ; subarachnoid haemorrhage (SAH) ; subarachnoid fibrosis ; scanning electron microscope (SEM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixty dogs with experimental subarachnoid haemorrhage (SAH), repeated SAH, and subarachnoid fibrosis (examined three weeks and three months after SAH, and treated with urokinase or dexamethasone) were examined by scanning electron microscope (SEM). The authors observed the resting and activated macrophages, the erythrophagocytosis, and giant cells in the subarachnoid space after SAH. They consider that the macrophages play an important role in the formation of subarachnoid fibrosis, similar to the role of macrophages in fibrosis in other sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01808524
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of antifibrinolytic therapy on subarachnoid fibrosis in dogs after experimental subarachnoid haemorrhage (1980)
    Springer
    Acta neurochirurgica 54 (1980), S. 17-24 
    Details
    ISSN: 0942-0940
    Keywords: Subarachnoid fibrosis ; subarachnoid haemorrhage (SAH) ; tranexamic acid ; antifibrinolytic therapy ; scanning electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of antifibrinolytic therapy on posthaemorrhagic subarachnoid fibrosis was observed experimentally in dogs with the scanning electron microscope (SEM). The subchronic subjects, given intravenous injections of tranexamic acid (1 mg/day) for 12 days and sacrificed 3 weeks after cisternal blood injection, showed residual clot with thick fibrosis, especially around the haemorrhage. The chronic subjects, to which the same procedure was applied and which were sacrificed three months after cisternal blood injection, showed significant increases in the subarachnoid fibrosis, most remarkably in the parasagittal region. Tranexamic acid is widely used for preventing the recurrence of subarachnoid haemorrhage. However, it was revealed in this study that antifibrinolytic therapy might increase chronic posthaemorrhagic subarachnoid fibrosis, which is considered to be responsible for communicating hydrocephalus by disturbing epicortical CSF flow4.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401939
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  • 3
    Electronic Resource
    Electronic Resource
    The influence of dexamethasone on subarachnoid fibrosis after subarachnoid haemorrhage (1979)
    Springer
    Acta neurochirurgica 51 (1979), S. 43-51 
    Details
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage (SAH) ; subarachnoid fibrosis ; dexamethasone ; scanning electron microscope (SEM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The author used the scanning electron microscope (SEM) to study the influence of dexamethasone on subarachnoid fibrosis after experimental subarachnoid haemorrhage (SAH). In the subchronic group of dogs, which were sacrificed three weeks after SAH, an average of 2.82 mg/kg intrathecal dexamethasone seemed to delay the fibrosis somewhat, but statistically showed no significant difference from the control group. In the chronic group, sacrificed three months after SAH, an average of 0.95 mg/kg intrathecal dexamethasone did not prevent the fibrosis, and no significant difference was found from the untreated dogs. The author considers that steroid therapy only delays and does not diminish the inflammatory process. This may also apply to other types of arachnoiditis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401793
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  • 4
    Electronic Resource
    Electronic Resource
    Prevention of subarachnoid fibrosis after subarachnoid haemorrhage with urokinase (1979)
    Springer
    Acta neurochirurgica 51 (1979), S. 53-61 
    Details
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage (SAH) ; subarachnoid fibrosis ; urokinase ; scanning electron microscope (SEM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The author used the scanning electron microscope (SEM) to study the influence of urokinase on subarachnoid fibrosis after experimental subarachnoid haemorrhage (SAH). In the subchronic group of dogs, which were sacrificed three weeks after SAH, an average of 45–50 IU/kg of intrathecal urokinase diminished the fibrosis. In the chronic group, which was sacrificed three months after SAH, an average of 250 IU/kg of intrathecal urokinase also had considerable reducing effect. The author supposes that fibrinolytic therapy, with lysis of blood clot, contributes to clearance of the blood. We contrast this mechanism with the mechanism and effect of antifibrinolytic therapy. This experiment is the first successful attempt to influence subarachnoid fibrosis, and also the first experiment in which subarachnoid fibrosis could to some extent be prevented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401794
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  • 5
    Electronic Resource
    Electronic Resource
    Arachnoid villi affected by subarachnoid pressure and haemorrhage (1979)
    Springer
    Acta neurochirurgica 51 (1979), S. 63-72 
    Details
    ISSN: 0942-0940
    Keywords: Arachnoid villi ; subarachnoid hemorrhage (SAH) ; increased subarachnoid pressure ; scanning electron microscope (SEM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The arachnoid villi of 18 dogs were studied. The authors confirmed the pressure gradient changes of the morphology of arachnoid villi of dogs with the scanning electron microscope (SEM). A subarachnoid infusion with 5–10 times higher pressure gradient than the physiological one, tore the superficial endothelial layer from the villi, and the inner part could also be observed stereoscopically. On the surface of the arachnoid villi the authors observed microvilli, openings of vacuoles and intercellular gaps, but did not find openings of preformed channels. After subarachnoid haemorrhage (SAH) generally the villi were blocked but the authors have observed a red blood cell escaping from a villus intercellularly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401795
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  • 6
    Electronic Resource
    Electronic Resource
    Biparieto-occipital craniotomy with hyperextended neck-“sea lion” position (1979)
    Springer
    Acta neurochirurgica 51 (1979), S. 113-117 
    Details
    ISSN: 0942-0940
    Keywords: Craniotomy ; operation ; pineal region ; tentorial incision
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors describe the prone position combined with a hyperextended neck and a biparieto-occipital approach for operation on pineal region tumours and for bilateral tentorial incision.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401802
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  • 7
    Electronic Resource
    Electronic Resource
    Neurinoma of spinal accessory nerve (1983)
    Springer
    Acta neurochirurgica 69 (1983), S. 219-224 
    Details
    ISSN: 0942-0940
    Keywords: Spinal accessory nerve ; neurinoma ; cisterna magna
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurinomas of the eleventh nerve can be divided into intracisternal and intrajugular types. A 50-year-old woman and a 29-year-old man had neurinomas of the spinal accessory nerve in the cisterna magna which were removed at operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401808
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  • 8
    Electronic Resource
    Electronic Resource
    The radiotherapy of cystic craniopharyngioma with intracystic installation of90Y silicate colloid (1985)
    Springer
    Acta neurochirurgica 74 (1985), S. 94-99 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors describe the intracavital treatment with90Y silicate colloid in 9 cases of cystic craniopharyngioma. The method has been applied since 1975 in the National Institute of Neurosurgery, Budapest. The intracavital treatment was only one among several applied treatment forms. In all patients a partial removal of the tumour has also been performed. The possibilities of evaluation of the effectiveness of the internal cyst irradiation are therefore limited. In most cases the intracavital treatment resulted in shrinkage of the cyst, or even was followed by its practical disappearence and the condition of the patients shows a decisive improvement. The growth of solid tumour parts is not influenced by this kind of treatment. Therefore the clinical improvement of the patient's condition depends also on the ratio between cyst and solid tumour volume. The optic nerve impairment did not improve in all cases. As a side-effect an oculomotor nerve paresis developed in several patients. Its possible explanations have been discussed, including lasting damage from tumour pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01418795
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  • 9
    Electronic Resource
    Electronic Resource
    Posterior fossa haemangioblastomas (1994)
    Springer
    Acta neurochirurgica 128 (1994), S. 109-114 
    Details
    ISSN: 0942-0940
    Keywords: Posterior fossa ; haemangioblastomas ; in-house software ; clinical analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 36 consecutive years' experience in treating 104 cases of posterior fossa haemangioblastomas is described and discussed. The mortality was 24%, with a tendency to decrease, reaching 20% in the last 15 years. About half the patients returned to neurological normality and full working capacity. Dividing the lesions into solid and cystic tumours, cystic tumours were more frequent, their survival was longer, recurrence less and postoperative state somewhat better.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400659
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  • 10
    Electronic Resource
    Electronic Resource
    Late post-irradiation necrosis of the brain (1979)
    Springer
    Acta neurochirurgica 46 (1979), S. 135-150 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three examples of late post-irradiation brain necrosis are reported. In two cases operation was performed on account of the space-occupying effects of the lesions, and in the third case the lesion was found post-mortem. The aetiology and pathology of the condition are discussed. Our findings in the three cases described are contrasted with those in 29 patients who had been submitted to similar doses of irradiation, but had not developed necrosis. The literature on pathogenesis is briefly reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01407687
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