ISSN:
1434-4475
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Malononitrile reacts with triethyl orthoformate,-orthoacetate,-orthopropionate and-orthobenzoate, resp., in the presence of different amounts of pyridine to ethoxymethylene-malononitriles and pyridinium 1,1,3,3-tetracyano-propenides, resp. The latter can easily be cyclised to 2-amino-6-chloro-3,5-dicyano-(4-alkyl and aryl, resp.)-pyridines. The synthesis of the α-aminopyridines can be carried out as one step reactions starting with malononitrile and orthoformate.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00898055
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