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  • 1
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A new method is being described for the determination of the electrolyte content of potassium, sodium and calcium in the intracellular and extracellular compartments of bone marrow cells of the rat. The cytostatic Proresid®-Sandoz (10 mg/100g rat per day) causes only little changes of the electrolyte content of bone marrow cells. Disturbances of the electrolyte metabolism occur when the daily dosage is rised to 20 mg Proresid per 100 g rat per day. After X-irradiation with high energy voltage (cobalt-60), high losses of intracellular potassium are observed. When irradiation and cytostatic are combined, a complete paralysis of membrane function becomes obvious: potassium and sodium pass into the extracellular compartment, whilst for the first time calcium can be traced in the intracellular compartment.
    Notes: Zusammenfassung Es wird über eine neue Methode zur Bestimmung der intra- und extrazellulären Elektrolytkonzentrationen von Knochenmarkzellen bei der Ratte berichtet. Nach Gabe eines Zytostatikums (Proresid, Sandoz) in einer Dosierung von 10 mg auf 100 g Ratte täglich, sind nur unwesentliche Elektrolytverschiebungen im intra- und extrazellulären Bereich vorhanden. Eine Verdoppelung der Dosis bewirkt stärkere Störungen des Elektrolytstoffwechsels. Nach einer Teilkörperbestrahlung mit 730 rad besteht ein signifikanter Abfall der intrazellulären Kalium-Elektrolytkonzentration, der sich über mehrere Tage hin verfolgen läßt. Eine Kombination von Teilkörperbestrahlung und Zytostatikumgabe führt zu einer vollständigen Paralyse der Membranfunktion von Knochenmarkzellen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 78 (1983), S. 7-12 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The uptake and metabolism of 14C-L-leucine by Cystoclonium purpureum (Huds) Batt. (Rhodophyllidaceae) at concentrations of 0.5–50 μM were studied. Leucine was taken up from seawater at rates of 10–160 nmol·g-1 fresh weight·h-1. At low leucine levels ( 5 μM) the amino acid was preferably incorporated into cellular protein; amine formation was less than 5%. However at leucine concentrations of 50 μM, more than 30% of the total leucine taken up was decarboxylated to 3-methylbutylamine. This effect is expressed even more in Dumontia increassata (O. F. Müll) Lamour. (Dumontiaceae). In both species some of the amine occurred as a non-volatile derivative (bound amine) from which free amine could quantitatively be released by acid hydrolysis. Leucine and amine uptake were inhibited by CCCP. However, from cells preloaded with both leucine and amine, only free amine is released in the presence of CCCP. The results indicate that decarboxylase activity will be switched on at increased levels of amino acids in seawater which may be expected frequently in habitats of littoral algae (tidal zone). A possible function of amine formation and release within the scope of chemical defence of benthic algae is discussed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1084
    Keywords: One-shot dual-energy subtraction imaging ; Laser-stimulated luminescence imaging plates ; Energy separation ; Computed radiography ; Chest diagnostics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Digital luminescent radiography enables dual-energy subtraction imaging, because this computed system allows susbtraction of imaging data and image post processing, as for example special windowing or edge enhancement. In a special cassette a copper filter is placed between two imaging plates for energy separation by a single X-ray exposure. Image post-processing with subtraction of imaging data permits the elimination of either skeleton or soft tissue structures. The influence of filter thickness, tube voltage and the X-ray exposure dosage on image quality is examined by the use of an anthropomorphic quality is examined by the use of an anthropomorphic phantom of the chest. According to our initial results dual energy subtraction imaging in one-shot-technique seems to be useful in the diagnostics of skeletal lesions and especially pulmonary nodules.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1084
    Keywords: Digital luminescence radiography ; Skeletal diagnosis ; Traumatology ; Standard digital images ; Image post-processing ; Creation of artefacts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the course of a comparative study 231 patients with traumatic lesions in skeletal and soft tissue areas were X-rayed using conventional film radiography and digital luminescence radiography (DLR). The results were evaluated by radiologists and traumatologists on the basis of optimised image post-processing in addition to the standard digital presentations. The imaging quality of compacta, spongiosa, soft tissues, fracture lines and osteosynthesis material was assessed in comparison with the screen-film images. Whereas the standard digital presentation in the “conventionally adjusted” imaging mode was inferior to the screen-film radiograph, the “edge-enhanced” standard presentation proved to be advantageous in the imaging of soft tissues (frequency of first-place ratings: DLR conventional 6%, screen-film system 21%, DLR edge-enhanced 31%). In the overall evaluation high-frequency filtered inverse image post-processing showed the highest diagnostic potential (frequency of first-place ratings: 41%). A conclusive assessment of metal implants is hindered by overshoot artefacts and can only be achieved through time-consuming post-processing of the stored image data.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 208 (1975), S. 299-308 
    ISSN: 1432-1459
    Keywords: Syringomyelia ; Normal pressure hydrocephalus ; Ventriculovenous shunt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An Hand eines eigenen Falles wird über die Syringomyelie bei gleichzeitig bestehendem Hydrocephalus berichtet und ein pathogenetischer Zusammenhang zwischen beiden Krankheitsbildern diskutiert. Nach Gardner führen Anomalien am Ausgang des 4. Ventrikels zur Ausbildung einer kommunizierenden Syringomyelie. Ein Normal Pressure Hydrocephalus kann nach Hakim u. Adams (1965) infolge des hydraulischen Preßeffekts diese Entwicklung fördern. Die ventrikulo-atriale Shunt-Operation stellt eine Möglichkeit dar, diesen Pathomechanismus zu unterbrechen und eine Besserung des Krankheitsbildes zu bewirken.
    Notes: Summary A case of syringomyelia with coexisting hydrocephalus is reported and a pathogenic relationship between both conditions is discussed. Gardner proposed that anomalies at the exit of the fourth ventricle produce a communicating syringomyelia. Hakim and Adams maintain that normal pressure hydrocephalus can aggravate this condition by a hydraulic pressure effect which can be stopped by the insertion of a ventriculoatrial shunt with improvement in the clinical picture. This has been our experience in the case reported.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 21 (1981), S. 259-263 
    ISSN: 1432-1920
    Keywords: Meningioma ; Multiple meningiomas ; Meningeal meningiomatosis ; von Recklinghausen's disease ; Primary meningeal sarcomatosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The same histological types of tumor are found in multiple as in solitary meningiomas. Multiple meningiomas cannot be considered in every case to be a forme fruste of von Recklinghausen's disease. The incidence of multiple meningiomas in this paper is higher than had been reported before the introduction of computed tomography (CT) into clinical practice. The number of tumor nodes is determined more accurately by CT than by angiography because tumors are detected in patients without neurological deficit. CT has limitations in the verification of small meningioma nodules near the base of the skull and in the differentiation of multiple meningiomas from meningeal meningiomatosis or primary meningeal sarcomatosis.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les données angiographiques, scintiphotographiques et pneumoencéphalographiques de 74 cas de gliome histologiquement vérifiés sot soumises à une interpretation aveugle. La comparaison des résultats montre qu'une combinaison des differéntes methodes donnent de meilleurs résultats que chaque méthode séparée.
    Abstract: Zusammenfassung Bei 74 histologisch gesicherten gliösen Tumoren wurden die vorliegenden Angiogramme, Szintifotos und Pneumencephalogramme blind reinterpretiert. Beim Vergleich der Ergebnisse zeigte sich, daß die für die einzelnen Methoden bekannten differentialdiagnostischen Schwierigkeiten bei Kombination der Verfahren erheblich gemindert werden.
    Notes: Summary Angiographic findings, scintiphotographs and pneumographic findings of 74 histological verified gliomas were subjected to blind reinterpretation. Comparison of the results proves that a combination of these examinations guarantees better results than each examination alone.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 16 (1978), S. 469-471 
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary CT findings in 51 patients with subdural hematomas are studied. Direct signs (hyperdensity, hypodensity) and indirect signs (any form of mass lesion) are distinguished. CT is limited with regard to determining correlations between time and the attenuation values. The factors which influence density of the hematoma are discussed. For a rational approach with subdural hematomas, which present diagnostic problems and reveal the limitations of CT diagnosis, a diagnostic scheme is proposed.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Sur le matériel d'une clinique neurochirurgicale, concernant 47 malades atteints de méningiome on démontre que la scintigraphie cérébrale au Technicium ost la méthode de choix pour le diagnostic des méningiomes. En ce qui concerne le diagnostic différentiel par rapport à la structure histologique, cette méthode atteint la même précision que l' angiographie. Des méningiomes de la convexité sont reconnus dans 100% des cas; le diagnostic étiologique est possible dans 88–90% des cas. Une bonne sécurité de diagnostic est également obtenue dans les cas de méningiome de la faux, du sphénoide et de la région olfactive.
    Abstract: Zusammenfassung Anhand eines neurochirurgischen Krankengutes von 47 Patienten wird demonstriert, daß die Hirnscintiphotographie mit 99mTc-Pertechnetat als Mehrphasentest eine sichere Lokalisation und Größenbestimmung intracranieller Meningiome erlaubt und in der Artdiagnose der Angiographie sicher nicht unterlegen ist. Nachweis und Lokalisation der Tumoren gelangen in 100% der Fälle, eine Artdiagnose bei 88–90% der Konvexitätsmeningiome. Eine sichere diagnostische Aussage ist auch bei den Meningiomen der Falx, des Keilbeines und der Olfaktoriusrinne möglich.
    Notes: Summary On the background of 47 patients of a neurosurgical clinic suffering from meningioma it can be stated that cerebral scintiphotography with Radiopertechnetate is a method to detect meningiomas with high effectiveness. As to the differentiation of the diagnosis referring to the tumour group, according to the histological structure this method reaches the results of angiographic examination. Meningiomas of the convexity are detected in 100 percent, the classification is possible in 88–90 percent. Reliable diagnosis can also be made of meningiomas of the falx, the sphenoid bone and the olfactory area.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 16 (1978), S. 472-473 
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The CT examinations described demonstrate the incidence of focal defects of cerebral substance corresponding to the aspect of a completed cerebral infarction. Progress of the disease over several years may induce a remarkable, mainly internal and cortical, cerebral atrophy, due to the vascular damage of the brain. That is why it is important to consider the possibility of a collagenous disease, particularly in the case of young patients, when a differential diagnosis is being made on the basis of such findings.
    Type of Medium: Electronic Resource
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