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  • 1
    Electronic Resource
    Electronic Resource
    25-Hydroxy-vitamin D levels in a patient with hypervitaminosis D (1978)
    Springer
    Journal of molecular medicine 56 (1978), S. 715-717 
    Details
    ISSN: 1432-1440
    Keywords: Vitamin D-Intoxikation ; 25-Hydroxy-Vitamin ; D-Serumspiegel ; Hypercalcämie ; Vitamin D intoxication ; Serum 25-hydroxy-vitamin D ; Hypercalcemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We measured the concentrations of serum calcium and 25-hydroxy-vitamin D in a patient with hypervitaminosis D during 3 months of therapy directed toward correcting the hypercalcemia. Serum calcium could not be maintained at normal concentration without specific therapy until 9 weeks after vitamin D was discontinued. Concentration of 25-hydroxy-vitamin D at the time was 285 ng/ml, approximately half of the value measured three weeks after withdrawal of vitamin D. Serial measurements of the concentration of 25-hydroxy-vitamin D seem to be a useful means of assessing the degree of intoxication in patients with hypervitaminosis D.
    Notes: Zusammenfassung Wir verfolgten die 25-Hydroxy-Vitamin D- und Calciumspiegel im Serum einer Patientin mit Vitamin D-Überdosierung unter calciumsenkender Therapie über drei Monate. Normale Serumcalciumspiegel fanden sich in einem therapiefreien Intervall erst 9 Wochen nach Beendigung der Vitamin D-Einnahme. Der 25-Hydroxy-Vitamin D-Spiegel lag zu diesem Zeitpunkt mit 285 ng/ml fast um die Hälfte niedriger als zu Beginn der Beobachtungszeit drei Wochen nach Absetzen des Vitamin D. Verlaufskontrollen der 25-Hydroxy-Vitamin D-Spiegel sind offenbar geeignet, das Ausmaß einer Vitamin D-Intoxikation abzuschätzen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02429107
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  • 2
    Electronic Resource
    Electronic Resource
    Serum gentamicin concentrations during intratracheal administration (1984)
    Springer
    Journal of molecular medicine 62 (1984), S. 394-398 
    Details
    ISSN: 1432-1440
    Keywords: Gentamicin serum concentration ; Intratracheal administration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In artificially ventilated patients, intratracheal aminoglycoside administration is used as a form of prophylaxis of broncho-pulmonary infections. In artificially ventilated patients with multiple organ failure, serum gentamicin concentrations were measured dependent on renal function after endotracheal administration. A standard commercial ampule of 40 mg gentamicin in a 1 ml solution was injected in undiluted form, intratracheally through the tubus, every 6 h. In the patients without renal failure, values over 1 µg/ml were only found in certain individual cases and reached a maximum of 1.5 µg/ml. In patients with renal failure even after prolonged application, the average serum concentrations were between 2 and 3.5 µg/ml. In a very few cases, however, levels of up to 10.5 µg/ml were measured. The daily serum pattern revealed a distinct dependence on the administration; 1 h after administration there was an increase in the serum concentrations which decreased to the initial levels after 6 h. When patients with renal impairment are given an aminoglycoside intratracheally, serum levels of up to 10.5 µg/ml may be reached and thus additional systemic aminoglycoside therapy should be avoided.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01742295
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Short communication
    Amsterdam : Elsevier
    Clinica Chimica Acta 70 (1976), S. 191-195 
    Details
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(76)90022-X
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  • 4
    Electronic Resource
    Electronic Resource
    Parathyroid hormone is normal in renal stone patients with idiopathic hypercalciuria and high fasting urinary calcium (1982)
    Springer
    Urological research 10 (1982), S. 205-207 
    Details
    ISSN: 1434-0879
    Keywords: Parathyroid hormone ; Calcium stone ; Idiopathic hypercalciuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a group of patients with idiopathic hypercalciuria and an increased fasting urinary calcium excretion we re-examined the question: does secondary hyperparathyroididsm exist? Eight out of 51 patients with calcium renal stones had a high calcium excretion in both fasting and in 24 h urines. The carboxyl-terminal immunoreactive PTH (iPTH) values in these patients were 16±5 ngeq/ml (M±SD), no higher than the iPTH values in the other groups, e.g. normocalciuric patients had an iPTH of 23±8 ngeq/ml. The existence of secondary hyperparathyroidism in a subgroup of stone patients with increased fasting urinary calcium excretion is questionable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255945
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  • 5
    Electronic Resource
    Electronic Resource
    Lateral spine dual-energy X-ray absorptiometry bone mineral measurement with fan-beam design: effect of osteophytic calcifications on lateral and anteroposterior spine BMD (1995)
    Springer
    Rheumatology international 15 (1995), S. 151-154 
    Details
    ISSN: 1437-160X
    Keywords: Lateral dual x-ray absorptiometry ; BMd ; Osteoarthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Recently, fan beam (FB) designs have been made available by several manufacturers (Aloka, Hologic Lunar and Sophar) to measure lumbar spine bone mineral area density (BMD) in both an anteroposterior (AP) and a lateral projection. The present study was performed to evaluate some characteristics of a new dual energy X-ray absorptiometry (DXA) system for supine lateral scans in normals and to study possible advantages for patients with ostcophytic calcifications (OC). The precision errors of in vitro and in vivo measurements were estimated by an anthropomorphic phantom and in healthy volunteers. To study the effect of osteoarthritic changes on AP and lateral DXA measurements, BMC (bone mineral content) and BMD were measured in age-matched women (n=150) with and without OC. Precision errors for lateral BMD in vitro over 1 and 6 months were 0.58/0.67% (slow/fast scan modes) and 0.67/0.77% (slow/fast scan modes), respectively. The short- and mid-term reproducibility of BMD values were 2% and 3.5%, respectively, using the compare function (3.5% and 7.5%, respectively, without the compare facility). The analysis of women with and without OC (n=150) demonstrated higher mean values for AP BMD (0.892±0.145 g/cm2) in patients with OC (n=75) than in normals (0.836±0.135 g/cm2, n=75, difference 6.3%). For lateral scans, BMD differed to a minor degree (3.1%) in patients with OC (0,629±0.133 g/cm2) compared with normals (0.610±0.117 g/cm2). Corresponding results were obtained in fast FB mode. Furthermore, we found significant (P〈0.0001) correlations between BMD in lateral and AP scans in patients without OC (r=0.63) and in patients with OC (r=0.75). Although the FB design facilitated fast AP and lateral scans, the higher precision errors of lateral scans could limit its application in longitudinal studies. The use of compare function should be recommended. However, BMD of lateral scans was less influenced by OC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00301772
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  • 6
    Electronic Resource
    Electronic Resource
    Plasma 25-hydroxyvitamin D and urinary cyclic AMP in German patients with subtotal gastrectomy (Billroth II) (1977)
    Springer
    Digestive diseases and sciences 22 (1977), S. 633-636 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In an attempt to clarify the pathogenesis of the disturbed calcium metabolism which sometimes follows partial gastrectomy, we determined plasma 25-hydroxyvitamin D (25-OH-D) concentrations and urinary cyclic 3′, 5′-adenosine monophosphate (cAMP) excretion in patients who had previously undergone Billroth II gastrectomy and who were without clinical evidence of bone disease. In 17 Billroth II patients plasma 25-OH-D concentrations were reduced (12.6±4.6 ng/ml, mean ±sd) compared to values in 17 control patients with diseases not affecting calcium metabolism (31.6±12.9 ng/ml,P〈0.001). Urinary cAMP excretion, in part reflecting parathyroid function, was higher in 17 Billroth II patients (5.0±2.5 μmol/day) than in the control patients (2.6±1.3 μmol/day,P〈0.001). These results suggest impaired nutrition of vitamin D and secondary hyperparathyroidism in Billroth II patients. While the cause of this phenomenon is unclear, it may contribute to the disturbance of calcium metabolism in patients who have had subtotal gastrectomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01073083
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