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  • 1
    Electronic Resource
    Electronic Resource
    Expérience du traitement Lyonnais à l'Hôpital Stéphanie (1994)
    Springer
    European journal of orthopaedic surgery & traumatology 4 (1994), S. 175-178 
    Details
    ISSN: 1432-1068
    Keywords: Idiopathic scoliosis ; Braces ; Scoliose idiopathique ; Corsets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Le traitement orthopédique des scolioses a évolué de façon spectaculaire à partir des années 60 avec l'apparition des plâtres collés, du cadre de Cotrel et des corsets lyonnais en plexidur. Jadis “opprobre de l'orthopédie”, la scoliose idiopathique a vu progressivement son pronostic s'éclairer, au prix cependant d'un traitement contraignant et de longue durée. Il faut cependant savoir moduler le traitement en fonction de plusieurs paramètres : l'importance de la scoliose, la localisation de la courbure, l'âge osseux, l'âge d'état civil. Le cas idéal pour le traitement orthopédique est celui d'une scoliose lombaire ou thoraco-lombaire avec un test de RISSER initial inférieur à 2. Pour les courbures thoraciques, le traitement orthopédique n'est à poursuivre que si le gain angulaire reste supérieur à 30 % au long du traitement, sinon, il vaut mieux cesser le traitement orthopédique et indiquer la chirurgie.
    Notes: Summary The conservative treatment of scolioses has evolved in a spectacular way from the 60's onwards with the birth of glued plasters, the Cotrel frame and the lyonnais braces in plexidur. In the past “the disgrace of orthopaedics”, idiopathic scoliosis progressively saw its prognosis brighten up, at the cost nevertheless of a constraining and lengthy treatment. However, the treatment must be varied depending on several parameters: the importance of the scoliosis, the localization of the curvature, the bone age, the chronological age. The ideal case for the conservative treatment is that of a lumbar or thoracolumbar scoliosis with an initial Risser test inferior to 2. For thoracic curvatures, the conservative treatment is continued only if the angular gain remains superior to 30% during treatment, otherwise, it is better to stop the conservative treatment and recommend the surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01788463
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  • 2
    Electronic Resource
    Electronic Resource
    PIXE channeling for concentration and location measurements of Zn- and Cd-dopants in InP single crystals
    Amsterdam : Elsevier
    Nuclear Inst. and Methods in Physics Research, B 75 (1993), S. 360-363 
    Details
    ISSN: 0168-583X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0168-583X(93)95675-U
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  • 3
    Electronic Resource
    Electronic Resource
    Isolation and purification of cat albumin from cat serum by copper ion affinity chromatography: further analysis of its primary structure
    Amsterdam : Elsevier
    Journal of Chromatography A 539 (1991), S. 475-484 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(01)83957-1
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  • 4
    Electronic Resource
    Electronic Resource
    Immobilized metal ion affinity chromatography for the purification of Fel d I, a cat major allergen, from a house-dust extract'
    Amsterdam : Elsevier
    Journal of Chromatography A 512 (1990), S. 177-188 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(01)89484-X
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  • 5
    Electronic Resource
    Electronic Resource
    Isolation of Der pI, the Dermatophagoides pteronyssinus major mite allergen, from a crude mite culture extract, purification by ion-chromatography, and comparison between the material obtained and a cDNA-coded Der pI
    Amsterdam : Elsevier
    Journal of Chromatography A 599 (1992), S. 105-111 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0021-9673(92)85462-3
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  • 6
    Electronic Resource
    Electronic Resource
    Vitamin D receptor gene polymorphism, bone mass, body size, and vitamin D receptor density (1995)
    Springer
    Calcified tissue international 57 (1995), S. 161-162 
    Details
    ISSN: 1432-0827
    Keywords: Bone mass ; Vitamin D receptor ; Body size ; VDR gene polymorphism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract We determined vitamin D receptor (VDR) gene alleles (based on the BsmI restriction site polymorphism), duodenal mucosal receptor density, bone mass at spine and total body, and body size in 32 healthy premenopausal females. While we found no relationship between allele and receptor density in duodenal mucosa, bone mineral content (BMC) at both spine and total body was significantly associated with VDR gene alleles. BMC was highest for the bb allele, lowest for BB, and intermediate for Bb. A similar association was noted between allele and body size variables, particularly weight. When BMC was adjusted for body weight, the association with VDR polymorphism disappeared. The VDR gene polymorphism may be affecting bone mass not through classical nutritional mechanisms (e.g., intestinal calcium absorption), but through an influence on body size.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00298438
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  • 7
    Electronic Resource
    Electronic Resource
    Caffeine and the calcium economy revisited (1995)
    Springer
    Osteoporosis international 5 (1995), S. 97-102 
    Details
    ISSN: 1433-2965
    Keywords: Caffeine ; Calcium absorption ; Calcium balance ; Calcium intake ; Urinary calcium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report an analysis of data from 560 calcium balance studies carried out on 190 women aged 34.8–69.3 years at the time of study. The main purposes were to confirm a previously observed association between caffeine intake and calcium balance, and to attribute the association, if possible, to specific component(s) of balance. We found a caffeine relationship such that for every 6 fl oz (177.5 ml) serving of caffeine-containing coffee, calcium balance was more negative by 0.114 mmol/day (4.6 mg/day) (P〈0.001). The relationship was localized to the input side of the balance equation, and both of its components (i.e. calcium intake and calcium absorption efficiency) were independently and inversely associated with caffeine intake. There was no evidence that the putative caffeine effect is confined to, or is greater among, subjects with low calcium intakes or those who are older or estrogen-deprived. The magnitude of the negative effect of caffeine on calcium balance suggests that it can be offset by increasing calcium intake by about 1 mmol (40 mg) for every 177.5 ml serving of caffeine-containing coffee.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01623310
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  • 8
    Electronic Resource
    Electronic Resource
    Vitamin D and its Major Metabolites: Serum Levels after Graded Oral Dosing in Healthy Men (1998)
    Springer
    Osteoporosis international 8 (1998), S. 222-230 
    Details
    ISSN: 1433-2965
    Keywords: Key words:1,25-Dihydroxycholecalciferol – 25-Hydroxycholecalciferol – Vitamin D
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We determined the quantitative relationships between graded oral dosing with vitamin D3, 25(OH)D3, and 1,25(OH)2D3 for short treatment periods and changes in circulating levels of these substances. The subjects were 116 healthy men (mean age, 28 + 4 years, with usual milk consumption of 40.47 l/day and mean serum 25(OH)D of 67 + 25 nmol/l). They were distributed among nine open-label treatment groups: vitamin D3 (25, 250 or 1250 mg/day for 8 weeks), 25(OH)D3 (10, 20 or 50 mg/day for 4 weeks) and 1,25(OH)2D3 (0.5, 1.0 or 1.0 mg/day for 2 weeks). All treatment occurred between January 3 and April 3. We measured fasting serum calcium, parathyroid hormone, vitamin D3, 25(OH)D and 1,25(OH)2D immediately before and after treatment. In the three groups treated with vitamin D3, mean values for circulating vitamin D3 increased by 13, 137 and 883 nmol/l and serum 25(OH)D increased by 29, 146 and 643 nmol/l for the three dosage groups, respectively. Treatment with 25(OH)D3 increased circulating 25(OH)D by 40, 76 and 206 nmol/l, respectively. Neither compound changed serum 1,25(OH)2D levels. However, treatment with 1,25(OH)2D3 increased circulating 1,25(OH)2D by 10, 46 and 60 pmol/l, respectively. Slopes calculated from these data allow the following estimates of mean treatment effects for typical dosage units in healthy 70-kg adults: an 8-week course of vitamin D3 at 10 mg/day (400 IU/day) would raise serum vitamin D by 9 nmol/l and serum 25(OH)D by 11 nmol/l; a 4-week course of 25(OH)D3 at 20 mg/day would raise serum 25(OH)D by 94 nmol/l; and a 2-week course of 1,25(OH)2D3 at 0.5 mg/day would raise serum 1,25(OH)2D by 17 pmol/l.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001980050058
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  • 9
    Electronic Resource
    Electronic Resource
    Association of Bone Dimensions with a Parathyroid Hormone Gene Polymorphism in Women (1999)
    Springer
    Osteoporosis international 9 (1999), S. 307-311 
    Details
    ISSN: 1433-2965
    Keywords: Key words:Bone – Metacarpal – Parathyroid hormone – Radiogrammetry – Radius
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We have recently shown that bone radiogrammetric dimensions are associated with vitamin D receptor gene polymorphism. Since parathyroid hormone (PTH) plays a central role in maintaining calcium homeostasis and in bone remodeling, we investigated whether bone radiogrammetric dimensions are associated with a PTH gene polymorphism in 91 healthy Caucasian women, who were premenopausal at entry into the study. These women had assessments of bone by radiogrammetry every five years for a median period of 20 years (range 4–27). DNA was extracted from white blood cells. A segment of the PTH gene with a polymorphism at a BstBI restriction site was amplified by polymerase chain reaction. Diameter, cortical thickness and cross-sectional area at standard sites of the metacarpals, radius and femur were measured with radiogrammetry. Higher metacarpal diameter and cross-sectional cortical area, and a slower decrease in radial cortical area with age, were associated with the absence of the BstBI restriction site of the PTH gene. PTH gene polymorphism accounts for about 7–9% of the total variances of bone dimensional variables. These findings suggest that the dimensions of long bones are influenced by allelic variations in the PTH gene or in genes nearby.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001980050152
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  • 10
    Electronic Resource
    Electronic Resource
    Absorption of Calcium as the Carbonate and Citrate Salts, with Some Observations on Method (1999)
    Springer
    Osteoporosis international 9 (1999), S. 19-23 
    Details
    ISSN: 1433-2965
    Keywords: Key words:Absorption method – Calcium absorption – Calcium carbonate – Calcium citrate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: Calcium supplement use has increased and there is confusion about the relative absorbability of various sources. Absorbability of calcium from the carbonate and citrate salts was compared at 300 mg and 1000 mg calcium loads, ingested as part of a light breakfast meal. Absorption was measured at the high load both by tracer appearance in serum and by the absorptive increment in urinary calcium, and at the low load by the tracer method only. Subjects were 37 healthy adult men and women, studied as outpatients, and each tested on both salts at the same load. Mean tracer absorption (± SD) for both salts combined was 36.0% at the 300 mg load and 28.4% at the 1000 mg load. In both experiments the observed mean difference in absorption between salts was very small. By the tracer method the within-subject difference (carbonate less citrate) was +3.3%± 1.2% of the ingested dose (mean ± SEM; P 〈0.05) at the high load, and at the low load, 3.6%± 2.7% (NS). Combining the two experiments yielded zero difference between sources. By the urinary calcium increment method, the mean difference between salts at the 1000 mg load was 1.8 ± 4.1 mg (NS). Side-by-side comparisons of the two methods revealed that the tracer method was 3 times more sensitive than the urinary increment method. We conclude that, when taken with food, calcium from the carbonate salt is fully as absorbable as from the citrate, and that the urinary increment method is not sufficiently sensitive to be useful in comparing sources in free-living subjects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001980050111
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